Consumption of walnuts suppresses the conversion of palmitic to palmitoleic acid and enhances omega-3 fatty acid metabolism in the heart of fructose-fed rats
Нема приказа
Аутори
Romić, Snježana Đ.Tepavčević, Snežana
Popović, Tamara
Zec, Manja
Stojiljković, Mojca D.
Ćulafić, Tijana
Bošković, Maja
Korićanac, Goran
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Walnut consumption mostly has a positive implication for cardiovascular health. Walnut diet effects on the cardiac fatty acid (FA) metabolism of healthy rats and those with fructose diet-induced metabolic burden were analysed. Both walnuts and fructose increased CD36 transporter level and the nuclear content of some/all of Lipin 1/PPARα/PGC-1 complex partners, as well as cytosolic and nuclear FOXO1. However, fructose, independently of walnuts, increased the content of palmitic (PA), oleic, and vaccenic acid (VA), while in walnut-fed rats failed to increase palmitoleic acid (POA) level and the POA/PA ratio, as well as total MUFA content. In opposite, walnuts reduced the level of PA and VA and increased alpha-linolenic, eicosapentaenoic and docosapentaenoic acid level, regardless of fructose. In conclusion, both fructose and walnuts stimulated the uptake and oxidation of FA in the heart, but the walnuts, opposite to fructose, favourably altered cardiac FA profile in healthy and metabolic...ally compromised rats.
Кључне речи:
fatty acid metabolism / Fructose-rich diet / heart / Walnut (Juglans regia)Извор:
International Journal of Food Sciences and Nutrition, 2022, 1-14Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200017 (Универзитет у Београду, Институт за нуклеарне науке Винча, Београд-Винча) (RS-MESTD-inst-2020-200017)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200015 (Универзитет у Београду, Институт за медицинска истраживања) (RS-MESTD-inst-2020-200015)
DOI: 10.1080/09637486.2022.2107186
ISSN: 0963-7486
PubMed: 35918845
WoS: 00083601010000
Scopus: 2-s2.0-85135304774
Институција/група
VinčaTY - JOUR AU - Romić, Snježana Đ. AU - Tepavčević, Snežana AU - Popović, Tamara AU - Zec, Manja AU - Stojiljković, Mojca D. AU - Ćulafić, Tijana AU - Bošković, Maja AU - Korićanac, Goran PY - 2022 UR - https://vinar.vin.bg.ac.rs/handle/123456789/10391 AB - Walnut consumption mostly has a positive implication for cardiovascular health. Walnut diet effects on the cardiac fatty acid (FA) metabolism of healthy rats and those with fructose diet-induced metabolic burden were analysed. Both walnuts and fructose increased CD36 transporter level and the nuclear content of some/all of Lipin 1/PPARα/PGC-1 complex partners, as well as cytosolic and nuclear FOXO1. However, fructose, independently of walnuts, increased the content of palmitic (PA), oleic, and vaccenic acid (VA), while in walnut-fed rats failed to increase palmitoleic acid (POA) level and the POA/PA ratio, as well as total MUFA content. In opposite, walnuts reduced the level of PA and VA and increased alpha-linolenic, eicosapentaenoic and docosapentaenoic acid level, regardless of fructose. In conclusion, both fructose and walnuts stimulated the uptake and oxidation of FA in the heart, but the walnuts, opposite to fructose, favourably altered cardiac FA profile in healthy and metabolically compromised rats. T2 - International Journal of Food Sciences and Nutrition T1 - Consumption of walnuts suppresses the conversion of palmitic to palmitoleic acid and enhances omega-3 fatty acid metabolism in the heart of fructose-fed rats SP - 1 EP - 14 DO - 10.1080/09637486.2022.2107186 ER -
@article{ author = "Romić, Snježana Đ. and Tepavčević, Snežana and Popović, Tamara and Zec, Manja and Stojiljković, Mojca D. and Ćulafić, Tijana and Bošković, Maja and Korićanac, Goran", year = "2022", abstract = "Walnut consumption mostly has a positive implication for cardiovascular health. Walnut diet effects on the cardiac fatty acid (FA) metabolism of healthy rats and those with fructose diet-induced metabolic burden were analysed. Both walnuts and fructose increased CD36 transporter level and the nuclear content of some/all of Lipin 1/PPARα/PGC-1 complex partners, as well as cytosolic and nuclear FOXO1. However, fructose, independently of walnuts, increased the content of palmitic (PA), oleic, and vaccenic acid (VA), while in walnut-fed rats failed to increase palmitoleic acid (POA) level and the POA/PA ratio, as well as total MUFA content. In opposite, walnuts reduced the level of PA and VA and increased alpha-linolenic, eicosapentaenoic and docosapentaenoic acid level, regardless of fructose. In conclusion, both fructose and walnuts stimulated the uptake and oxidation of FA in the heart, but the walnuts, opposite to fructose, favourably altered cardiac FA profile in healthy and metabolically compromised rats.", journal = "International Journal of Food Sciences and Nutrition", title = "Consumption of walnuts suppresses the conversion of palmitic to palmitoleic acid and enhances omega-3 fatty acid metabolism in the heart of fructose-fed rats", pages = "1-14", doi = "10.1080/09637486.2022.2107186" }
Romić, S. Đ., Tepavčević, S., Popović, T., Zec, M., Stojiljković, M. D., Ćulafić, T., Bošković, M.,& Korićanac, G.. (2022). Consumption of walnuts suppresses the conversion of palmitic to palmitoleic acid and enhances omega-3 fatty acid metabolism in the heart of fructose-fed rats. in International Journal of Food Sciences and Nutrition, 1-14. https://doi.org/10.1080/09637486.2022.2107186
Romić SĐ, Tepavčević S, Popović T, Zec M, Stojiljković MD, Ćulafić T, Bošković M, Korićanac G. Consumption of walnuts suppresses the conversion of palmitic to palmitoleic acid and enhances omega-3 fatty acid metabolism in the heart of fructose-fed rats. in International Journal of Food Sciences and Nutrition. 2022;:1-14. doi:10.1080/09637486.2022.2107186 .
Romić, Snježana Đ., Tepavčević, Snežana, Popović, Tamara, Zec, Manja, Stojiljković, Mojca D., Ćulafić, Tijana, Bošković, Maja, Korićanac, Goran, "Consumption of walnuts suppresses the conversion of palmitic to palmitoleic acid and enhances omega-3 fatty acid metabolism in the heart of fructose-fed rats" in International Journal of Food Sciences and Nutrition (2022):1-14, https://doi.org/10.1080/09637486.2022.2107186 . .