Magnetic nano- and micro-particles based on Gd-substituted magnetite with improved colloidal stability
Само за регистроване кориснике
2021
Чланак у часопису (Објављена верзија)
,
© 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature
Метаподаци
Приказ свих података о документуАпстракт
A series of Fe3-xGdxO4 (x = 0, 0.1, 0.2) nanoparticles with an average diameter of around 8 nm were prepared by the coprecipitation method and coated by citric acid (CA). The nanoparticles show superparamagnetic behavior at room temperature and transition to a blocked state, at a temperature from ~ 89 K to ~ 213 K, depending on Gd concentration. The saturation magnetization of Fe3-xGdxO4 tended to drop for samples with a higher content of Gd. High colloidal stability is mandatory in medical applications of magnetic nanoparticles, and here we demonstrate a new procedure for its improvement. A colloidal sample of Fe3O4@CA was mechanically milled, after which dynamic light scattering and zeta potential measurements were used to monitor the hydrodynamic size and colloidal stability of the acquired suspensions. After 90 min of milling, the average hydrodynamic diameter decreased by 40%, and size distribution changed from polymodal to monomodal, while the negative zeta potential increased fr...om − 30.5 mV to − 52.8 mV. Additionally, Fe2.80Gd0.20O4@CA nanoparticles were embedded in human serum albumin to produce magnetic microspheres (MMS), which could be used as a drug delivery platform. FE-SEM images showed that magnetic nanoparticles form clusters within MMS. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.
Кључне речи:
Albumin microspheres / Fluid ball milling / Magnetic nanoparticlesИзвор:
Applied Physics. A: Materials Science and Processing, 2021, 127, 5, 372-Финансирање / пројекти:
- Serbia-Slovakia bilateral project SK-SRB-18-0055
- Slovak Research and Development Agency (APP) [DS-FR-19-0052]
DOI: 10.1007/s00339-021-04509-6
ISSN: 0947-8396
WoS: 000681059600003
Scopus: 2-s2.0-85104830685
Колекције
Институција/група
VinčaTY - JOUR AU - Bošković, Marko AU - Fabián, Martin AU - Vranješ-Đurić, Sanja AU - Antić, Bratislav PY - 2021 UR - https://vinar.vin.bg.ac.rs/handle/123456789/9699 AB - A series of Fe3-xGdxO4 (x = 0, 0.1, 0.2) nanoparticles with an average diameter of around 8 nm were prepared by the coprecipitation method and coated by citric acid (CA). The nanoparticles show superparamagnetic behavior at room temperature and transition to a blocked state, at a temperature from ~ 89 K to ~ 213 K, depending on Gd concentration. The saturation magnetization of Fe3-xGdxO4 tended to drop for samples with a higher content of Gd. High colloidal stability is mandatory in medical applications of magnetic nanoparticles, and here we demonstrate a new procedure for its improvement. A colloidal sample of Fe3O4@CA was mechanically milled, after which dynamic light scattering and zeta potential measurements were used to monitor the hydrodynamic size and colloidal stability of the acquired suspensions. After 90 min of milling, the average hydrodynamic diameter decreased by 40%, and size distribution changed from polymodal to monomodal, while the negative zeta potential increased from − 30.5 mV to − 52.8 mV. Additionally, Fe2.80Gd0.20O4@CA nanoparticles were embedded in human serum albumin to produce magnetic microspheres (MMS), which could be used as a drug delivery platform. FE-SEM images showed that magnetic nanoparticles form clusters within MMS. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature. T2 - Applied Physics. A: Materials Science and Processing T1 - Magnetic nano- and micro-particles based on Gd-substituted magnetite with improved colloidal stability VL - 127 IS - 5 SP - 372 DO - 10.1007/s00339-021-04509-6 ER -
@article{ author = "Bošković, Marko and Fabián, Martin and Vranješ-Đurić, Sanja and Antić, Bratislav", year = "2021", abstract = "A series of Fe3-xGdxO4 (x = 0, 0.1, 0.2) nanoparticles with an average diameter of around 8 nm were prepared by the coprecipitation method and coated by citric acid (CA). The nanoparticles show superparamagnetic behavior at room temperature and transition to a blocked state, at a temperature from ~ 89 K to ~ 213 K, depending on Gd concentration. The saturation magnetization of Fe3-xGdxO4 tended to drop for samples with a higher content of Gd. High colloidal stability is mandatory in medical applications of magnetic nanoparticles, and here we demonstrate a new procedure for its improvement. A colloidal sample of Fe3O4@CA was mechanically milled, after which dynamic light scattering and zeta potential measurements were used to monitor the hydrodynamic size and colloidal stability of the acquired suspensions. After 90 min of milling, the average hydrodynamic diameter decreased by 40%, and size distribution changed from polymodal to monomodal, while the negative zeta potential increased from − 30.5 mV to − 52.8 mV. Additionally, Fe2.80Gd0.20O4@CA nanoparticles were embedded in human serum albumin to produce magnetic microspheres (MMS), which could be used as a drug delivery platform. FE-SEM images showed that magnetic nanoparticles form clusters within MMS. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.", journal = "Applied Physics. A: Materials Science and Processing", title = "Magnetic nano- and micro-particles based on Gd-substituted magnetite with improved colloidal stability", volume = "127", number = "5", pages = "372", doi = "10.1007/s00339-021-04509-6" }
Bošković, M., Fabián, M., Vranješ-Đurić, S.,& Antić, B.. (2021). Magnetic nano- and micro-particles based on Gd-substituted magnetite with improved colloidal stability. in Applied Physics. A: Materials Science and Processing, 127(5), 372. https://doi.org/10.1007/s00339-021-04509-6
Bošković M, Fabián M, Vranješ-Đurić S, Antić B. Magnetic nano- and micro-particles based on Gd-substituted magnetite with improved colloidal stability. in Applied Physics. A: Materials Science and Processing. 2021;127(5):372. doi:10.1007/s00339-021-04509-6 .
Bošković, Marko, Fabián, Martin, Vranješ-Đurić, Sanja, Antić, Bratislav, "Magnetic nano- and micro-particles based on Gd-substituted magnetite with improved colloidal stability" in Applied Physics. A: Materials Science and Processing, 127, no. 5 (2021):372, https://doi.org/10.1007/s00339-021-04509-6 . .