Radiobiological studies on the 62 MeV therapeutic proton beam at lns catania: II. facs analyses of HTB140 melanoma cells
Аутори
Ristić-Fira, AleksandraTodorović, Danijela V.
Cirrone, Giuseppe Antonio Pablo
Cuttone, Giacomo
Valastro, Lucia M.
Petrović, Ivan M.
Конференцијски прилог (Објављена верзија)
,
Society of Physical Chemists of Serbia
Метаподаци
Приказ свих података о документуАпстракт
The objective of this study was to determine whether apoptosis and cell cycle redistribution were influenced by high-LET irradiation. Exponentially growing HTB140 cells were exposed to an unmodulated 62 MeV proton beam, within the Bragg peak, delivered over the single dose range from 8 Gy to 24 Gy. At 6 h post-irradiation, there was a low level of early apoptosis. At 48 h irradiated cells were more damaged, showing the increase in number of apoptotic nuclei. The dose dependent cell cycle phase distribution was detected at 48 h post-irradiation. The cell population exhibited phase redistribution toward G2/M phase.
Извор:
Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry, 2004, 1, 429-431Издавач:
- Society of Physical Chemists of Serbia
Напомена:
- Physical chemistry 2004 : 7th international conference on fundamental and applied aspects of physical chemistry; Belgrade (Serbia); 21-23 September 2004
Колекције
Институција/група
VinčaTY - CONF AU - Ristić-Fira, Aleksandra AU - Todorović, Danijela V. AU - Cirrone, Giuseppe Antonio Pablo AU - Cuttone, Giacomo AU - Valastro, Lucia M. AU - Petrović, Ivan M. PY - 2004 UR - https://vinar.vin.bg.ac.rs/handle/123456789/9507 AB - The objective of this study was to determine whether apoptosis and cell cycle redistribution were influenced by high-LET irradiation. Exponentially growing HTB140 cells were exposed to an unmodulated 62 MeV proton beam, within the Bragg peak, delivered over the single dose range from 8 Gy to 24 Gy. At 6 h post-irradiation, there was a low level of early apoptosis. At 48 h irradiated cells were more damaged, showing the increase in number of apoptotic nuclei. The dose dependent cell cycle phase distribution was detected at 48 h post-irradiation. The cell population exhibited phase redistribution toward G2/M phase. PB - Society of Physical Chemists of Serbia C3 - Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry T1 - Radiobiological studies on the 62 MeV therapeutic proton beam at lns catania: II. facs analyses of HTB140 melanoma cells VL - 1 SP - 429 EP - 431 UR - https://hdl.handle.net/21.15107/rcub_vinar_9507 ER -
@conference{ author = "Ristić-Fira, Aleksandra and Todorović, Danijela V. and Cirrone, Giuseppe Antonio Pablo and Cuttone, Giacomo and Valastro, Lucia M. and Petrović, Ivan M.", year = "2004", abstract = "The objective of this study was to determine whether apoptosis and cell cycle redistribution were influenced by high-LET irradiation. Exponentially growing HTB140 cells were exposed to an unmodulated 62 MeV proton beam, within the Bragg peak, delivered over the single dose range from 8 Gy to 24 Gy. At 6 h post-irradiation, there was a low level of early apoptosis. At 48 h irradiated cells were more damaged, showing the increase in number of apoptotic nuclei. The dose dependent cell cycle phase distribution was detected at 48 h post-irradiation. The cell population exhibited phase redistribution toward G2/M phase.", publisher = "Society of Physical Chemists of Serbia", journal = "Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry", title = "Radiobiological studies on the 62 MeV therapeutic proton beam at lns catania: II. facs analyses of HTB140 melanoma cells", volume = "1", pages = "429-431", url = "https://hdl.handle.net/21.15107/rcub_vinar_9507" }
Ristić-Fira, A., Todorović, D. V., Cirrone, G. A. P., Cuttone, G., Valastro, L. M.,& Petrović, I. M.. (2004). Radiobiological studies on the 62 MeV therapeutic proton beam at lns catania: II. facs analyses of HTB140 melanoma cells. in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry Society of Physical Chemists of Serbia., 1, 429-431. https://hdl.handle.net/21.15107/rcub_vinar_9507
Ristić-Fira A, Todorović DV, Cirrone GAP, Cuttone G, Valastro LM, Petrović IM. Radiobiological studies on the 62 MeV therapeutic proton beam at lns catania: II. facs analyses of HTB140 melanoma cells. in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry. 2004;1:429-431. https://hdl.handle.net/21.15107/rcub_vinar_9507 .
Ristić-Fira, Aleksandra, Todorović, Danijela V., Cirrone, Giuseppe Antonio Pablo, Cuttone, Giacomo, Valastro, Lucia M., Petrović, Ivan M., "Radiobiological studies on the 62 MeV therapeutic proton beam at lns catania: II. facs analyses of HTB140 melanoma cells" in Physical chemistry 2004: 7th international conference on fundemental and applied aspract of physical chemistry, 1 (2004):429-431, https://hdl.handle.net/21.15107/rcub_vinar_9507 .