Dependence of the quality of SALDI TOF MS analysis on the TiO2 nanocrystals size and shape
Samo za registrovane korisnike
2016
Autori
Popović, Iva A.Milovanović, Dubravka S.
Miletić, Jadranka
Nešić, Maja D.
Vranješ, Mila
Šaponjić, Zoran
Petković, Marijana
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Titanium dioxide is widely used substrate for laser desorption and ionization [(SA)LDI] mass spectrometry. As the semiconductor with high UV absorbance and rapid energy transfer to analytes, TiO2 provides soft and efficient desorption/ionization of analytes with relatively low degrees of fragmentation in the gas phase. TiO2 nanocrystals are convenient for small molecules (molecular mass LT 1000 Da) analysis due to low number of background signals. Desorption/ionization processes on TiO2 nanocrystals are related to the physical properties of the substrate, such as the ability to absorb and dissipate energy from the irradiating laser light source. In addition, size and shape of nanocrystals also affect these abilities. The aim of this study is to investigate the influence of shape and size dependant TiO2 nanocrystals/UV laser interaction on the quality of the mass spectra, detectability of analyzed molecules, intensities of the signals and homogeneity of co-crystals onto the MALDI plate,... of carbohydrates. It is shown that the size and shape of nanocrystals influenced the way of packing carbohydrates onto plate, and thus affects homogeneity and reproducibility of mass spectrometry analysis.
Ključne reči:
SALDI TOF MS / TiO2 nanocrystals / HomogeneityIzvor:
Optical and Quantum Electronics, 2016, 48, 2Izdavač:
- Springer
Finansiranje / projekti:
- Ispitivanje mehanizma reakcija kompleksa jona prelaznih metala sa biološki značajnim molekulima (RS-MESTD-Basic Research (BR or ON)-172011)
- Uticaj veličine, oblika i strukture nanočestica na njihova svojstva i svojstva nanokompozita (RS-MESTD-Basic Research (BR or ON)-172056)
- Efekti dejstva laserskog zračenja i plazme na savremene materijale pri njihovoj sintezi, modifikaciji i analizi (RS-MESTD-Basic Research (BR or ON)-172019)
DOI: 10.1007/s11082-016-0413-5
ISSN: 0306-8919; 1572-817X
WoS: 000368741200037
Scopus: 2-s2.0-84955321884
Kolekcije
Institucija/grupa
VinčaTY - JOUR AU - Popović, Iva A. AU - Milovanović, Dubravka S. AU - Miletić, Jadranka AU - Nešić, Maja D. AU - Vranješ, Mila AU - Šaponjić, Zoran AU - Petković, Marijana PY - 2016 UR - https://vinar.vin.bg.ac.rs/handle/123456789/902 AB - Titanium dioxide is widely used substrate for laser desorption and ionization [(SA)LDI] mass spectrometry. As the semiconductor with high UV absorbance and rapid energy transfer to analytes, TiO2 provides soft and efficient desorption/ionization of analytes with relatively low degrees of fragmentation in the gas phase. TiO2 nanocrystals are convenient for small molecules (molecular mass LT 1000 Da) analysis due to low number of background signals. Desorption/ionization processes on TiO2 nanocrystals are related to the physical properties of the substrate, such as the ability to absorb and dissipate energy from the irradiating laser light source. In addition, size and shape of nanocrystals also affect these abilities. The aim of this study is to investigate the influence of shape and size dependant TiO2 nanocrystals/UV laser interaction on the quality of the mass spectra, detectability of analyzed molecules, intensities of the signals and homogeneity of co-crystals onto the MALDI plate, of carbohydrates. It is shown that the size and shape of nanocrystals influenced the way of packing carbohydrates onto plate, and thus affects homogeneity and reproducibility of mass spectrometry analysis. PB - Springer T2 - Optical and Quantum Electronics T1 - Dependence of the quality of SALDI TOF MS analysis on the TiO2 nanocrystals size and shape VL - 48 IS - 2 DO - 10.1007/s11082-016-0413-5 ER -
@article{ author = "Popović, Iva A. and Milovanović, Dubravka S. and Miletić, Jadranka and Nešić, Maja D. and Vranješ, Mila and Šaponjić, Zoran and Petković, Marijana", year = "2016", abstract = "Titanium dioxide is widely used substrate for laser desorption and ionization [(SA)LDI] mass spectrometry. As the semiconductor with high UV absorbance and rapid energy transfer to analytes, TiO2 provides soft and efficient desorption/ionization of analytes with relatively low degrees of fragmentation in the gas phase. TiO2 nanocrystals are convenient for small molecules (molecular mass LT 1000 Da) analysis due to low number of background signals. Desorption/ionization processes on TiO2 nanocrystals are related to the physical properties of the substrate, such as the ability to absorb and dissipate energy from the irradiating laser light source. In addition, size and shape of nanocrystals also affect these abilities. The aim of this study is to investigate the influence of shape and size dependant TiO2 nanocrystals/UV laser interaction on the quality of the mass spectra, detectability of analyzed molecules, intensities of the signals and homogeneity of co-crystals onto the MALDI plate, of carbohydrates. It is shown that the size and shape of nanocrystals influenced the way of packing carbohydrates onto plate, and thus affects homogeneity and reproducibility of mass spectrometry analysis.", publisher = "Springer", journal = "Optical and Quantum Electronics", title = "Dependence of the quality of SALDI TOF MS analysis on the TiO2 nanocrystals size and shape", volume = "48", number = "2", doi = "10.1007/s11082-016-0413-5" }
Popović, I. A., Milovanović, D. S., Miletić, J., Nešić, M. D., Vranješ, M., Šaponjić, Z.,& Petković, M.. (2016). Dependence of the quality of SALDI TOF MS analysis on the TiO2 nanocrystals size and shape. in Optical and Quantum Electronics Springer., 48(2). https://doi.org/10.1007/s11082-016-0413-5
Popović IA, Milovanović DS, Miletić J, Nešić MD, Vranješ M, Šaponjić Z, Petković M. Dependence of the quality of SALDI TOF MS analysis on the TiO2 nanocrystals size and shape. in Optical and Quantum Electronics. 2016;48(2). doi:10.1007/s11082-016-0413-5 .
Popović, Iva A., Milovanović, Dubravka S., Miletić, Jadranka, Nešić, Maja D., Vranješ, Mila, Šaponjić, Zoran, Petković, Marijana, "Dependence of the quality of SALDI TOF MS analysis on the TiO2 nanocrystals size and shape" in Optical and Quantum Electronics, 48, no. 2 (2016), https://doi.org/10.1007/s11082-016-0413-5 . .