Electrochemistry of the Arrow Poison, Tubocurarine, Using Boron Doped Diamond Electrode: Experimental and Theoretical Approaches
Само за регистроване кориснике
2019
Аутори
Đurđić, SlađanaStanković, Vesna
Perić, Marko R.
Ognjanović, Miloš
Švorc, Lubomir
Mutić, Jelena J.
Stanković, Dalibor M.
Чланак у часопису (Објављена верзија)
,
© 2019 The Electrochemical Society
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In present work boron doped diamond (BDD) electrode was applied for studying electrochemical behavior, as well as for quantitative determination of natural alkaloid, tubocurarine (arrow poison/ TUB). Electrochemical behavior was investigated using several organic solvents and aqueous buffers, at different pHs, as supporting electrolytes. After selection of the most appropriate supporting electrolyte and investigation of its electrochemical behavior, analytical procedures for quantitative analysis of TUB were developed in an acetonitrile/methanol (80:20) mixture and in 1 mol L−1 nitric acid, which had linear quantification ranges from 4 × 10−6 to 1 × 10−4 mol L−1 (LOD = 3.07 × 10−6 mol L−1) and 4 × 10−6 to 9 × 10−5 mol L−1 (LOD = 2.45 × 10−6 mol L−1 and 5.28 × 10−7 mol L−1, depending on the selected peak), respectively. The oxidation mechanism of TUB was proposed from the theoretical aspect. Remarkable selectivity and good sensitivity were obtained after the TUB quantification method wa...s optimized, allowing application of the developed method for TUB quantification in biological fluids, with excellent reproducibility, accuracy and precision.
Извор:
Journal of The Electrochemical Society, 2019, 166, 14, G157-G161Финансирање / пројекти:
- Примена унапређених оксидационих процеса и наноструктурисаних оксидних материјала за уклањање загађивача из животне средине, развој и оптимизација инструменталних техника за праћење ефикасности (RS-MESTD-Basic Research (BR or ON)-172030)
- Grant Agency of the Slovak Republic [1/0489/16]
DOI: 10.1149/2.1241914jes
ISSN: 0013-4651
WoS: 000490166300001
Scopus: 2-s2.0-85074076971
Колекције
Институција/група
VinčaTY - JOUR AU - Đurđić, Slađana AU - Stanković, Vesna AU - Perić, Marko R. AU - Ognjanović, Miloš AU - Švorc, Lubomir AU - Mutić, Jelena J. AU - Stanković, Dalibor M. PY - 2019 UR - https://vinar.vin.bg.ac.rs/handle/123456789/8615 AB - In present work boron doped diamond (BDD) electrode was applied for studying electrochemical behavior, as well as for quantitative determination of natural alkaloid, tubocurarine (arrow poison/ TUB). Electrochemical behavior was investigated using several organic solvents and aqueous buffers, at different pHs, as supporting electrolytes. After selection of the most appropriate supporting electrolyte and investigation of its electrochemical behavior, analytical procedures for quantitative analysis of TUB were developed in an acetonitrile/methanol (80:20) mixture and in 1 mol L−1 nitric acid, which had linear quantification ranges from 4 × 10−6 to 1 × 10−4 mol L−1 (LOD = 3.07 × 10−6 mol L−1) and 4 × 10−6 to 9 × 10−5 mol L−1 (LOD = 2.45 × 10−6 mol L−1 and 5.28 × 10−7 mol L−1, depending on the selected peak), respectively. The oxidation mechanism of TUB was proposed from the theoretical aspect. Remarkable selectivity and good sensitivity were obtained after the TUB quantification method was optimized, allowing application of the developed method for TUB quantification in biological fluids, with excellent reproducibility, accuracy and precision. T2 - Journal of The Electrochemical Society T1 - Electrochemistry of the Arrow Poison, Tubocurarine, Using Boron Doped Diamond Electrode: Experimental and Theoretical Approaches VL - 166 IS - 14 SP - G157 EP - G161 DO - 10.1149/2.1241914jes ER -
@article{ author = "Đurđić, Slađana and Stanković, Vesna and Perić, Marko R. and Ognjanović, Miloš and Švorc, Lubomir and Mutić, Jelena J. and Stanković, Dalibor M.", year = "2019", abstract = "In present work boron doped diamond (BDD) electrode was applied for studying electrochemical behavior, as well as for quantitative determination of natural alkaloid, tubocurarine (arrow poison/ TUB). Electrochemical behavior was investigated using several organic solvents and aqueous buffers, at different pHs, as supporting electrolytes. After selection of the most appropriate supporting electrolyte and investigation of its electrochemical behavior, analytical procedures for quantitative analysis of TUB were developed in an acetonitrile/methanol (80:20) mixture and in 1 mol L−1 nitric acid, which had linear quantification ranges from 4 × 10−6 to 1 × 10−4 mol L−1 (LOD = 3.07 × 10−6 mol L−1) and 4 × 10−6 to 9 × 10−5 mol L−1 (LOD = 2.45 × 10−6 mol L−1 and 5.28 × 10−7 mol L−1, depending on the selected peak), respectively. The oxidation mechanism of TUB was proposed from the theoretical aspect. Remarkable selectivity and good sensitivity were obtained after the TUB quantification method was optimized, allowing application of the developed method for TUB quantification in biological fluids, with excellent reproducibility, accuracy and precision.", journal = "Journal of The Electrochemical Society", title = "Electrochemistry of the Arrow Poison, Tubocurarine, Using Boron Doped Diamond Electrode: Experimental and Theoretical Approaches", volume = "166", number = "14", pages = "G157-G161", doi = "10.1149/2.1241914jes" }
Đurđić, S., Stanković, V., Perić, M. R., Ognjanović, M., Švorc, L., Mutić, J. J.,& Stanković, D. M.. (2019). Electrochemistry of the Arrow Poison, Tubocurarine, Using Boron Doped Diamond Electrode: Experimental and Theoretical Approaches. in Journal of The Electrochemical Society, 166(14), G157-G161. https://doi.org/10.1149/2.1241914jes
Đurđić S, Stanković V, Perić MR, Ognjanović M, Švorc L, Mutić JJ, Stanković DM. Electrochemistry of the Arrow Poison, Tubocurarine, Using Boron Doped Diamond Electrode: Experimental and Theoretical Approaches. in Journal of The Electrochemical Society. 2019;166(14):G157-G161. doi:10.1149/2.1241914jes .
Đurđić, Slađana, Stanković, Vesna, Perić, Marko R., Ognjanović, Miloš, Švorc, Lubomir, Mutić, Jelena J., Stanković, Dalibor M., "Electrochemistry of the Arrow Poison, Tubocurarine, Using Boron Doped Diamond Electrode: Experimental and Theoretical Approaches" in Journal of The Electrochemical Society, 166, no. 14 (2019):G157-G161, https://doi.org/10.1149/2.1241914jes . .