Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit
Authorized Users Only
2015
Authors
Bernal, Mario A.Bordage, Marie Claude
Brown, Jeremy Michael Cooney
Davídková, Marie
Delage, E.
El Bitar, Ziad Ei
Enger, Shirin A.
Francis, Ziad
Guatelli, Susanna
Ivanchenko, Vladimir N.
Karamitros, Mathieu
Kyriakou, Ioanna
Maigne, Lydia
Meylan, Sylvain
Murakami, Kouichi
Okada, Shogo
Payno, H.
Perrot, Yann
Petrović, Ivan M.
Pham, Q. T.
Ristić-Fira, Aleksandra
Sasaki, Takashi
Stepan, Vaclav
Tran, Ngoc Hoang
Villagrasa, Carmen
Incerti, Sebastien
Article (Published version)
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Show full item recordAbstract
Understanding the fundamental mechanisms involved in the induction of biological damage by ionizing radiation remains a major challenge of todays radiobiology research. The Monte Carlo simulation of physical, physicochemical and chemical processes involved may provide a powerful tool for the simulation of early damage induction. The Geant4-DNA extension of the general purpose Monte Carlo Geant4 simulation toolkit aims to provide the scientific community with an open source access platform for the mechanistic simulation of such early damage. This paper presents the most recent review of the Geant4-DNA extension, as available to Geant4 users since June 2015 (release 10.2 Beta). In particular, the review includes the description of new physical models for the description of electron elastic and inelastic interactions in liquid water, as well as new examples dedicated to the simulation of physicochemical and chemical stages of water radiolysis. Several implementations of geometrical models... of biological targets are presented as well, and the list of Geant4-DNA examples is described.
Keywords:
Monte Carlo / Geant4-DNA / Radiolysis / Radiobiology / Ionizing radiationSource:
Physica Medica, 2015, 31, 8, 861-874Funding / projects:
- FAPESP foundation in Brazil [2011/51594-2]
- European Space Agency through the BioRadII [4000107387/12/NL/AK]
DOI: 10.1016/j.ejmp.2015.10.087
ISSN: 1120-1797; 1724-191X
PubMed: 26653251
WoS: 000366660400003
Scopus: 2-s2.0-84959529519
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VinčaTY - JOUR AU - Bernal, Mario A. AU - Bordage, Marie Claude AU - Brown, Jeremy Michael Cooney AU - Davídková, Marie AU - Delage, E. AU - El Bitar, Ziad Ei AU - Enger, Shirin A. AU - Francis, Ziad AU - Guatelli, Susanna AU - Ivanchenko, Vladimir N. AU - Karamitros, Mathieu AU - Kyriakou, Ioanna AU - Maigne, Lydia AU - Meylan, Sylvain AU - Murakami, Kouichi AU - Okada, Shogo AU - Payno, H. AU - Perrot, Yann AU - Petrović, Ivan M. AU - Pham, Q. T. AU - Ristić-Fira, Aleksandra AU - Sasaki, Takashi AU - Stepan, Vaclav AU - Tran, Ngoc Hoang AU - Villagrasa, Carmen AU - Incerti, Sebastien PY - 2015 UR - https://vinar.vin.bg.ac.rs/handle/123456789/859 AB - Understanding the fundamental mechanisms involved in the induction of biological damage by ionizing radiation remains a major challenge of todays radiobiology research. The Monte Carlo simulation of physical, physicochemical and chemical processes involved may provide a powerful tool for the simulation of early damage induction. The Geant4-DNA extension of the general purpose Monte Carlo Geant4 simulation toolkit aims to provide the scientific community with an open source access platform for the mechanistic simulation of such early damage. This paper presents the most recent review of the Geant4-DNA extension, as available to Geant4 users since June 2015 (release 10.2 Beta). In particular, the review includes the description of new physical models for the description of electron elastic and inelastic interactions in liquid water, as well as new examples dedicated to the simulation of physicochemical and chemical stages of water radiolysis. Several implementations of geometrical models of biological targets are presented as well, and the list of Geant4-DNA examples is described. T2 - Physica Medica T1 - Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit VL - 31 IS - 8 SP - 861 EP - 874 DO - 10.1016/j.ejmp.2015.10.087 ER -
@article{ author = "Bernal, Mario A. and Bordage, Marie Claude and Brown, Jeremy Michael Cooney and Davídková, Marie and Delage, E. and El Bitar, Ziad Ei and Enger, Shirin A. and Francis, Ziad and Guatelli, Susanna and Ivanchenko, Vladimir N. and Karamitros, Mathieu and Kyriakou, Ioanna and Maigne, Lydia and Meylan, Sylvain and Murakami, Kouichi and Okada, Shogo and Payno, H. and Perrot, Yann and Petrović, Ivan M. and Pham, Q. T. and Ristić-Fira, Aleksandra and Sasaki, Takashi and Stepan, Vaclav and Tran, Ngoc Hoang and Villagrasa, Carmen and Incerti, Sebastien", year = "2015", abstract = "Understanding the fundamental mechanisms involved in the induction of biological damage by ionizing radiation remains a major challenge of todays radiobiology research. The Monte Carlo simulation of physical, physicochemical and chemical processes involved may provide a powerful tool for the simulation of early damage induction. The Geant4-DNA extension of the general purpose Monte Carlo Geant4 simulation toolkit aims to provide the scientific community with an open source access platform for the mechanistic simulation of such early damage. This paper presents the most recent review of the Geant4-DNA extension, as available to Geant4 users since June 2015 (release 10.2 Beta). In particular, the review includes the description of new physical models for the description of electron elastic and inelastic interactions in liquid water, as well as new examples dedicated to the simulation of physicochemical and chemical stages of water radiolysis. Several implementations of geometrical models of biological targets are presented as well, and the list of Geant4-DNA examples is described.", journal = "Physica Medica", title = "Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit", volume = "31", number = "8", pages = "861-874", doi = "10.1016/j.ejmp.2015.10.087" }
Bernal, M. A., Bordage, M. C., Brown, J. M. C., Davídková, M., Delage, E., El Bitar, Z. E., Enger, S. A., Francis, Z., Guatelli, S., Ivanchenko, V. N., Karamitros, M., Kyriakou, I., Maigne, L., Meylan, S., Murakami, K., Okada, S., Payno, H., Perrot, Y., Petrović, I. M., Pham, Q. T., Ristić-Fira, A., Sasaki, T., Stepan, V., Tran, N. H., Villagrasa, C.,& Incerti, S.. (2015). Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit. in Physica Medica, 31(8), 861-874. https://doi.org/10.1016/j.ejmp.2015.10.087
Bernal MA, Bordage MC, Brown JMC, Davídková M, Delage E, El Bitar ZE, Enger SA, Francis Z, Guatelli S, Ivanchenko VN, Karamitros M, Kyriakou I, Maigne L, Meylan S, Murakami K, Okada S, Payno H, Perrot Y, Petrović IM, Pham QT, Ristić-Fira A, Sasaki T, Stepan V, Tran NH, Villagrasa C, Incerti S. Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit. in Physica Medica. 2015;31(8):861-874. doi:10.1016/j.ejmp.2015.10.087 .
Bernal, Mario A., Bordage, Marie Claude, Brown, Jeremy Michael Cooney, Davídková, Marie, Delage, E., El Bitar, Ziad Ei, Enger, Shirin A., Francis, Ziad, Guatelli, Susanna, Ivanchenko, Vladimir N., Karamitros, Mathieu, Kyriakou, Ioanna, Maigne, Lydia, Meylan, Sylvain, Murakami, Kouichi, Okada, Shogo, Payno, H., Perrot, Yann, Petrović, Ivan M., Pham, Q. T., Ristić-Fira, Aleksandra, Sasaki, Takashi, Stepan, Vaclav, Tran, Ngoc Hoang, Villagrasa, Carmen, Incerti, Sebastien, "Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit" in Physica Medica, 31, no. 8 (2015):861-874, https://doi.org/10.1016/j.ejmp.2015.10.087 . .