Antibacterial effects of new endodontic materials based on calcium silicates
Antibakterijski efekti novih endodontskih materijala na bazi kalcijum silikata
Autori
Trišić, DijanaĆetenović, Bojana
Zdravković, Nemanja M.
Marković, Tatjana
Dojčinović, Biljana P.
Jokanović, Vukoman R.
Marković, Dejan
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Background/Aim. The main task of endodontic treatment is to eliminate pathologically altered tissue, to disinfect root canal space and to obtain its three-dimensional hermetic obturation. The main purpose of this study was to evaluate antimicrobial activity of new endodontic nano-structured highly active calcium silicates based materials albo-mineral plyoxide carbonate aggregate (ALBO-MPCA) and calcium silicates (CS) in comparison to mineral trioxide aggregate (MTA+) and UltraCal XS (CH). Methods. The antimicrobial activity of materials was tested against Staphylococcus aureus (ATCC 25923) and Enterococcus faecalis (ATCC 14506) strains, and following clinical isolates: Rothia dentocariosa, Enterococcus faecalis, Staphylococcus aureus, Streptococcus anginosus and Streptococcus vestibularis using a double layer agar diffusion test. The pH measurements were performed using the pH meter. Total amount of released ions was determined by inductively coupled plasma optical emission spectrometr...y (ICP-OES). Results. All tested materials showed the best antibacterial potential after 1 h of incubation. After 3h and 24h of the incubation period, the antibacterial potential of all tested materials were similar. The Agar diffusion test showed that ALBO-MPCA, CS and MTA+ had similar inhibition zones (p > 0.05), except in the activity against Staphylococcus aureus where ALBO-MPCA showed better antimicrobial properties than MTA+ in 3h and 24h of the incubation period (p < 0.05). Following 24h of the incubation, the inhibition zones were the strongest with CH against Staphylococcus aureus (16.67 ± 2.34 mm) followed by ALBO-MPCA (14.67 ± 1.21 mm) and the weakest with CS against Enterococcus faecalis (6.50 ± 1.76 mm). CH showed the highest pH, followed by ALBO-MPCA, CS and MTA+. Conclusion. The expressed antibacterial effects indicate that materials based on nano-structured highly active calcium silicates represent effective therapeutic agents for root canal obturation in one-visit apexification treatment, therefore they are recommend for further examination and clinical trials as they are proposed for MTA substitution. © 2019, Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved.
Ključne reči:
dental pulp diseases / root canal preparation / calcium silicate / calcium hydroxide / anti-infective agentsIzvor:
Vojnosanitetski pregled, 2019, 76, 4, 365-372Finansiranje / projekti:
- Hemijsko i strukturno dizajniranje nanomaterijala za primenu u medicini i inženjerstvu tkiva (RS-MESTD-Basic Research (BR or ON)-172026)
- Uvođenje i evaluacija nove molekularne metode za brzo otkrivanje mecA gena stafilokoka direktno u brisevima uzetim od ljudi, životinja i iz njihovog okruženja (RS-MESTD-Technological Development (TD or TR)-31079)
DOI: 10.2298/VSP161231130T
ISSN: 0042-8450
WoS: 000504432700002
Scopus: 2-s2.0-85069738071
Kolekcije
Institucija/grupa
VinčaTY - JOUR AU - Trišić, Dijana AU - Ćetenović, Bojana AU - Zdravković, Nemanja M. AU - Marković, Tatjana AU - Dojčinović, Biljana P. AU - Jokanović, Vukoman R. AU - Marković, Dejan PY - 2019 UR - https://vinar.vin.bg.ac.rs/handle/123456789/8426 AB - Background/Aim. The main task of endodontic treatment is to eliminate pathologically altered tissue, to disinfect root canal space and to obtain its three-dimensional hermetic obturation. The main purpose of this study was to evaluate antimicrobial activity of new endodontic nano-structured highly active calcium silicates based materials albo-mineral plyoxide carbonate aggregate (ALBO-MPCA) and calcium silicates (CS) in comparison to mineral trioxide aggregate (MTA+) and UltraCal XS (CH). Methods. The antimicrobial activity of materials was tested against Staphylococcus aureus (ATCC 25923) and Enterococcus faecalis (ATCC 14506) strains, and following clinical isolates: Rothia dentocariosa, Enterococcus faecalis, Staphylococcus aureus, Streptococcus anginosus and Streptococcus vestibularis using a double layer agar diffusion test. The pH measurements were performed using the pH meter. Total amount of released ions was determined by inductively coupled plasma optical emission spectrometry (ICP-OES). Results. All tested materials showed the best antibacterial potential after 1 h of incubation. After 3h and 24h of the incubation period, the antibacterial potential of all tested materials were similar. The Agar diffusion test showed that ALBO-MPCA, CS and MTA+ had similar inhibition zones (p > 0.05), except in the activity against Staphylococcus aureus where ALBO-MPCA showed better antimicrobial properties than MTA+ in 3h and 24h of the incubation period (p < 0.05). Following 24h of the incubation, the inhibition zones were the strongest with CH against Staphylococcus aureus (16.67 ± 2.34 mm) followed by ALBO-MPCA (14.67 ± 1.21 mm) and the weakest with CS against Enterococcus faecalis (6.50 ± 1.76 mm). CH showed the highest pH, followed by ALBO-MPCA, CS and MTA+. Conclusion. The expressed antibacterial effects indicate that materials based on nano-structured highly active calcium silicates represent effective therapeutic agents for root canal obturation in one-visit apexification treatment, therefore they are recommend for further examination and clinical trials as they are proposed for MTA substitution. © 2019, Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved. T2 - Vojnosanitetski pregled T1 - Antibacterial effects of new endodontic materials based on calcium silicates VL - 76 IS - 4 SP - 365 EP - 372 DO - 10.2298/VSP161231130T ER -
@article{ author = "Trišić, Dijana and Ćetenović, Bojana and Zdravković, Nemanja M. and Marković, Tatjana and Dojčinović, Biljana P. and Jokanović, Vukoman R. and Marković, Dejan", year = "2019", abstract = "Background/Aim. The main task of endodontic treatment is to eliminate pathologically altered tissue, to disinfect root canal space and to obtain its three-dimensional hermetic obturation. The main purpose of this study was to evaluate antimicrobial activity of new endodontic nano-structured highly active calcium silicates based materials albo-mineral plyoxide carbonate aggregate (ALBO-MPCA) and calcium silicates (CS) in comparison to mineral trioxide aggregate (MTA+) and UltraCal XS (CH). Methods. The antimicrobial activity of materials was tested against Staphylococcus aureus (ATCC 25923) and Enterococcus faecalis (ATCC 14506) strains, and following clinical isolates: Rothia dentocariosa, Enterococcus faecalis, Staphylococcus aureus, Streptococcus anginosus and Streptococcus vestibularis using a double layer agar diffusion test. The pH measurements were performed using the pH meter. Total amount of released ions was determined by inductively coupled plasma optical emission spectrometry (ICP-OES). Results. All tested materials showed the best antibacterial potential after 1 h of incubation. After 3h and 24h of the incubation period, the antibacterial potential of all tested materials were similar. The Agar diffusion test showed that ALBO-MPCA, CS and MTA+ had similar inhibition zones (p > 0.05), except in the activity against Staphylococcus aureus where ALBO-MPCA showed better antimicrobial properties than MTA+ in 3h and 24h of the incubation period (p < 0.05). Following 24h of the incubation, the inhibition zones were the strongest with CH against Staphylococcus aureus (16.67 ± 2.34 mm) followed by ALBO-MPCA (14.67 ± 1.21 mm) and the weakest with CS against Enterococcus faecalis (6.50 ± 1.76 mm). CH showed the highest pH, followed by ALBO-MPCA, CS and MTA+. Conclusion. The expressed antibacterial effects indicate that materials based on nano-structured highly active calcium silicates represent effective therapeutic agents for root canal obturation in one-visit apexification treatment, therefore they are recommend for further examination and clinical trials as they are proposed for MTA substitution. © 2019, Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved.", journal = "Vojnosanitetski pregled", title = "Antibacterial effects of new endodontic materials based on calcium silicates", volume = "76", number = "4", pages = "365-372", doi = "10.2298/VSP161231130T" }
Trišić, D., Ćetenović, B., Zdravković, N. M., Marković, T., Dojčinović, B. P., Jokanović, V. R.,& Marković, D.. (2019). Antibacterial effects of new endodontic materials based on calcium silicates. in Vojnosanitetski pregled, 76(4), 365-372. https://doi.org/10.2298/VSP161231130T
Trišić D, Ćetenović B, Zdravković NM, Marković T, Dojčinović BP, Jokanović VR, Marković D. Antibacterial effects of new endodontic materials based on calcium silicates. in Vojnosanitetski pregled. 2019;76(4):365-372. doi:10.2298/VSP161231130T .
Trišić, Dijana, Ćetenović, Bojana, Zdravković, Nemanja M., Marković, Tatjana, Dojčinović, Biljana P., Jokanović, Vukoman R., Marković, Dejan, "Antibacterial effects of new endodontic materials based on calcium silicates" in Vojnosanitetski pregled, 76, no. 4 (2019):365-372, https://doi.org/10.2298/VSP161231130T . .