Disposable Biosensor Based on Amidase/CeO2/GNR Modified Inkjet‐printed CNT Electrodes‐droplet Based Paracetamol Detection in Biological Fluids for “Point‐of‐care” Applications
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2019
Authors
Stanković, Dalibor M.Ognjanović, Miloš
Jović, Milica
Cuplić, Valentina
Lesch, Andreas
Girault, Hubert H.
Gavrović-Jankulović, Marija
Antić, Bratislav
Article (Published version)
,
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
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A disposable acetaminophen biosensor based on inkjet-printed CNT electrodes (IJPCNT) modified with amidase/cerium dioxide@graphene nanoribbons composite was developed (ACeO2@GNR/IJPCNT). The enzyme amidase A was used for the first time as a recognition element. Inkjet-printed CNT electrodes served as a basis for the construction of a biosensor that enables droplet detection using 5 μL sample volume. The biosensor showed high selectivity, sensitivity, a low detection limit of 0.18 μM and a wide working linear range from 1 to 100 μM. The proposed approach allows fast and reliable detection of acetaminophen in biological fluids with negligible matrix effect and remarkable reproducibility. © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
Keywords:
acetaminophen / amidase / biosensor / cerium dioxide / graphene nanoribbons composite / inkjet-printed sensorsSource:
Electroanalysis, 2019, 31, 8, 1517-1525Funding / projects:
- Strengthening of the MagBioVin Research and Innovation Team for Development of Novel Approaches for Tumour Therapy based on Nanostructured Materials (EU-621375)
- Application of advanced oxidation processes and nanostructured oxide materials for the removal of pollutants from the environment, development and optimisation of instrumental techniques for efficiency monitoring (RS-172030)
- Allergens, antibodies, enzymes and small physiologically important molecules: design, structure, function and relevance (RS-172049)
DOI: 10.1002/elan.201900129
ISSN: 1040-0397; 1521-4109
WoS: 000479081100015
Scopus: 2-s2.0-85066899420
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VinčaTY - JOUR AU - Stanković, Dalibor M. AU - Ognjanović, Miloš AU - Jović, Milica AU - Cuplić, Valentina AU - Lesch, Andreas AU - Girault, Hubert H. AU - Gavrović-Jankulović, Marija AU - Antić, Bratislav PY - 2019 UR - https://vinar.vin.bg.ac.rs/handle/123456789/8342 AB - A disposable acetaminophen biosensor based on inkjet-printed CNT electrodes (IJPCNT) modified with amidase/cerium dioxide@graphene nanoribbons composite was developed (ACeO2@GNR/IJPCNT). The enzyme amidase A was used for the first time as a recognition element. Inkjet-printed CNT electrodes served as a basis for the construction of a biosensor that enables droplet detection using 5 μL sample volume. The biosensor showed high selectivity, sensitivity, a low detection limit of 0.18 μM and a wide working linear range from 1 to 100 μM. The proposed approach allows fast and reliable detection of acetaminophen in biological fluids with negligible matrix effect and remarkable reproducibility. © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim T2 - Electroanalysis T1 - Disposable Biosensor Based on Amidase/CeO2/GNR Modified Inkjet‐printed CNT Electrodes‐droplet Based Paracetamol Detection in Biological Fluids for “Point‐of‐care” Applications VL - 31 IS - 8 SP - 1517 EP - 1525 DO - 10.1002/elan.201900129 ER -
@article{ author = "Stanković, Dalibor M. and Ognjanović, Miloš and Jović, Milica and Cuplić, Valentina and Lesch, Andreas and Girault, Hubert H. and Gavrović-Jankulović, Marija and Antić, Bratislav", year = "2019", abstract = "A disposable acetaminophen biosensor based on inkjet-printed CNT electrodes (IJPCNT) modified with amidase/cerium dioxide@graphene nanoribbons composite was developed (ACeO2@GNR/IJPCNT). The enzyme amidase A was used for the first time as a recognition element. Inkjet-printed CNT electrodes served as a basis for the construction of a biosensor that enables droplet detection using 5 μL sample volume. The biosensor showed high selectivity, sensitivity, a low detection limit of 0.18 μM and a wide working linear range from 1 to 100 μM. The proposed approach allows fast and reliable detection of acetaminophen in biological fluids with negligible matrix effect and remarkable reproducibility. © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim", journal = "Electroanalysis", title = "Disposable Biosensor Based on Amidase/CeO2/GNR Modified Inkjet‐printed CNT Electrodes‐droplet Based Paracetamol Detection in Biological Fluids for “Point‐of‐care” Applications", volume = "31", number = "8", pages = "1517-1525", doi = "10.1002/elan.201900129" }
Stanković, D. M., Ognjanović, M., Jović, M., Cuplić, V., Lesch, A., Girault, H. H., Gavrović-Jankulović, M.,& Antić, B.. (2019). Disposable Biosensor Based on Amidase/CeO2/GNR Modified Inkjet‐printed CNT Electrodes‐droplet Based Paracetamol Detection in Biological Fluids for “Point‐of‐care” Applications. in Electroanalysis, 31(8), 1517-1525. https://doi.org/10.1002/elan.201900129
Stanković DM, Ognjanović M, Jović M, Cuplić V, Lesch A, Girault HH, Gavrović-Jankulović M, Antić B. Disposable Biosensor Based on Amidase/CeO2/GNR Modified Inkjet‐printed CNT Electrodes‐droplet Based Paracetamol Detection in Biological Fluids for “Point‐of‐care” Applications. in Electroanalysis. 2019;31(8):1517-1525. doi:10.1002/elan.201900129 .
Stanković, Dalibor M., Ognjanović, Miloš, Jović, Milica, Cuplić, Valentina, Lesch, Andreas, Girault, Hubert H., Gavrović-Jankulović, Marija, Antić, Bratislav, "Disposable Biosensor Based on Amidase/CeO2/GNR Modified Inkjet‐printed CNT Electrodes‐droplet Based Paracetamol Detection in Biological Fluids for “Point‐of‐care” Applications" in Electroanalysis, 31, no. 8 (2019):1517-1525, https://doi.org/10.1002/elan.201900129 . .