Carbon Quantum Dots Modified Polyurethane Nanocomposite as Effective Photocatalytic and Antibacterial Agents
Samo za registrovane korisnike
2018
Autori
Kovačova, MariaMarković, Zoran M.
Humpoliček, Petr
Mičušik, Matej
Švajdlenkova, Helena
Kleinova, Angela
Danko, Martin
Kubat, Pavel
Vajdak, Jan
Capakova, Zdenka
Lehocky, Marian
Munster, Lukaš
Todorović-Marković, Biljana
Špitalsky, Zdenko
Članak u časopisu (Objavljena verzija)
,
© 2018 American Chemical Society
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Development of new types of antibacterial coatings or nanocomposites is of great importance due to widespread multidrug-resistant infections including bacterial infections. Herein, we investigated biocompatibility as well as structural, photocatalytic, and antibacterial properties of photoactive hydrophobic carbon quantum dots/polyurethane nanocomposite. The swell-encapsulation-shrink method was applied for production of these nanocomposites. Hydrophobic carbon quantum dots/polyurethane nanocomposites were found to be highly effective generator of singlet oxygen upon irradiation by low-power blue light. Analysis of conducted antibacterial tests on Staphyloccocus aureus and Escherichia coli showed 5-log bactericidal effect of these nanocomposites within 60 min of irradiation. Very powerful degradation of dye (rose bengal) was observed within 180 min of blue light irradiation of the nanocomposites. Biocompatibility studies revealed that nanocomposites were not cytotoxic against mouse emb...ryonic fibroblast cell line, whereas they showed moderate cytotoxicity toward adenocarcinomic human epithelial cell line. Minor hemolytic effect of these nanocomposites toward red blood cells was revealed.
Ključne reči:
hydrophobic carbon quantum dots / polyurethane / reactive oxygen species production / photocatalytic activity / antibacterial activity / visible light sterilization / hydrophobic carbon quantum dots / polyurethane / reactive oxygen species production / photocatalytic activity / antibacterial activity / visible light sterilizationIzvor:
ACS Biomaterials Science and Engineering, 2018, 4, 12, 3983-3993Finansiranje / projekti:
- SASPRO Programme (No. 1237/02/02-b)
- People Programme (Marie Curie Actions) European Union's Seventh Framework Programme under REA (No. 609427)
- VEGA [2/0093/16]
- Czech Science Foundation (17-05095S)
- Tanki slojevi jednoslojnih ugljeničnih nanotuba i grafena za primenu u elektronici (RS-MESTD-Basic Research (BR or ON)-172003)
- Bilateral project Serbia-Slovakia (SK-SRB-2016-0038)
- Multilateral scientific and technological cooperation in the Danube region (DS-2016-021)
DOI: 10.1021/acsbiomaterials.8b00582
ISSN: 2373-9878
WoS: 000453109000007
Scopus: 2-s2.0-85054970446
URI
http://pubs.acs.org/doi/10.1021/acsbiomaterials.8b00582https://vinar.vin.bg.ac.rs/handle/123456789/8064
Kolekcije
Institucija/grupa
VinčaTY - JOUR AU - Kovačova, Maria AU - Marković, Zoran M. AU - Humpoliček, Petr AU - Mičušik, Matej AU - Švajdlenkova, Helena AU - Kleinova, Angela AU - Danko, Martin AU - Kubat, Pavel AU - Vajdak, Jan AU - Capakova, Zdenka AU - Lehocky, Marian AU - Munster, Lukaš AU - Todorović-Marković, Biljana AU - Špitalsky, Zdenko PY - 2018 UR - http://pubs.acs.org/doi/10.1021/acsbiomaterials.8b00582 UR - https://vinar.vin.bg.ac.rs/handle/123456789/8064 AB - Development of new types of antibacterial coatings or nanocomposites is of great importance due to widespread multidrug-resistant infections including bacterial infections. Herein, we investigated biocompatibility as well as structural, photocatalytic, and antibacterial properties of photoactive hydrophobic carbon quantum dots/polyurethane nanocomposite. The swell-encapsulation-shrink method was applied for production of these nanocomposites. Hydrophobic carbon quantum dots/polyurethane nanocomposites were found to be highly effective generator of singlet oxygen upon irradiation by low-power blue light. Analysis of conducted antibacterial tests on Staphyloccocus aureus and Escherichia coli showed 5-log bactericidal effect of these nanocomposites within 60 min of irradiation. Very powerful degradation of dye (rose bengal) was observed within 180 min of blue light irradiation of the nanocomposites. Biocompatibility studies revealed that nanocomposites were not cytotoxic against mouse embryonic fibroblast cell line, whereas they showed moderate cytotoxicity toward adenocarcinomic human epithelial cell line. Minor hemolytic effect of these nanocomposites toward red blood cells was revealed. T2 - ACS Biomaterials Science and Engineering T1 - Carbon Quantum Dots Modified Polyurethane Nanocomposite as Effective Photocatalytic and Antibacterial Agents VL - 4 IS - 12 SP - 3983 EP - 3993 DO - 10.1021/acsbiomaterials.8b00582 ER -
@article{ author = "Kovačova, Maria and Marković, Zoran M. and Humpoliček, Petr and Mičušik, Matej and Švajdlenkova, Helena and Kleinova, Angela and Danko, Martin and Kubat, Pavel and Vajdak, Jan and Capakova, Zdenka and Lehocky, Marian and Munster, Lukaš and Todorović-Marković, Biljana and Špitalsky, Zdenko", year = "2018", abstract = "Development of new types of antibacterial coatings or nanocomposites is of great importance due to widespread multidrug-resistant infections including bacterial infections. Herein, we investigated biocompatibility as well as structural, photocatalytic, and antibacterial properties of photoactive hydrophobic carbon quantum dots/polyurethane nanocomposite. The swell-encapsulation-shrink method was applied for production of these nanocomposites. Hydrophobic carbon quantum dots/polyurethane nanocomposites were found to be highly effective generator of singlet oxygen upon irradiation by low-power blue light. Analysis of conducted antibacterial tests on Staphyloccocus aureus and Escherichia coli showed 5-log bactericidal effect of these nanocomposites within 60 min of irradiation. Very powerful degradation of dye (rose bengal) was observed within 180 min of blue light irradiation of the nanocomposites. Biocompatibility studies revealed that nanocomposites were not cytotoxic against mouse embryonic fibroblast cell line, whereas they showed moderate cytotoxicity toward adenocarcinomic human epithelial cell line. Minor hemolytic effect of these nanocomposites toward red blood cells was revealed.", journal = "ACS Biomaterials Science and Engineering", title = "Carbon Quantum Dots Modified Polyurethane Nanocomposite as Effective Photocatalytic and Antibacterial Agents", volume = "4", number = "12", pages = "3983-3993", doi = "10.1021/acsbiomaterials.8b00582" }
Kovačova, M., Marković, Z. M., Humpoliček, P., Mičušik, M., Švajdlenkova, H., Kleinova, A., Danko, M., Kubat, P., Vajdak, J., Capakova, Z., Lehocky, M., Munster, L., Todorović-Marković, B.,& Špitalsky, Z.. (2018). Carbon Quantum Dots Modified Polyurethane Nanocomposite as Effective Photocatalytic and Antibacterial Agents. in ACS Biomaterials Science and Engineering, 4(12), 3983-3993. https://doi.org/10.1021/acsbiomaterials.8b00582
Kovačova M, Marković ZM, Humpoliček P, Mičušik M, Švajdlenkova H, Kleinova A, Danko M, Kubat P, Vajdak J, Capakova Z, Lehocky M, Munster L, Todorović-Marković B, Špitalsky Z. Carbon Quantum Dots Modified Polyurethane Nanocomposite as Effective Photocatalytic and Antibacterial Agents. in ACS Biomaterials Science and Engineering. 2018;4(12):3983-3993. doi:10.1021/acsbiomaterials.8b00582 .
Kovačova, Maria, Marković, Zoran M., Humpoliček, Petr, Mičušik, Matej, Švajdlenkova, Helena, Kleinova, Angela, Danko, Martin, Kubat, Pavel, Vajdak, Jan, Capakova, Zdenka, Lehocky, Marian, Munster, Lukaš, Todorović-Marković, Biljana, Špitalsky, Zdenko, "Carbon Quantum Dots Modified Polyurethane Nanocomposite as Effective Photocatalytic and Antibacterial Agents" in ACS Biomaterials Science and Engineering, 4, no. 12 (2018):3983-3993, https://doi.org/10.1021/acsbiomaterials.8b00582 . .