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dc.creatorJokanović, Vukoman R.
dc.creatorČolović, Božana M.
dc.creatorProkić, Bogomir Bolka
dc.creatorTomanović, Nada
dc.creatorPopović Bajić, Marijana
dc.creatorŽivković, Slavoljub
dc.date.accessioned2019-02-27T13:50:37Z
dc.date.available2019-02-27T13:50:37Z
dc.date.issued2018
dc.identifier.issn1687-8434 (print)
dc.identifier.issn1687-8442 (electronic)
dc.identifier.urihttps://www.hindawi.com/journals/amse/2018/8493439/
dc.identifier.urihttp://vinar.vin.bg.ac.rs/handle/123456789/8061
dc.description.abstractAs an alternative to MTA, a new endodontic material based on hydroxyapatite and calcium silicates (ALBO-MPSA) has been synthesized, and its biocompatibility has been studied in many in vitro and in vivo studies. The current study aims to evaluate a subchronic systemic toxicity of ALBO-MPSA on the rat animal model, as a continuation of the previous studies. Biochemical parameters of blood and histological parameters of the liver, kidneys, and spleen of the rats were analyzed after 120 days of consumption of the aqueous extract of ALBO-MPSA. The results showed no myelotoxic effect or autoimmune effect on peripheral blood cells and no pathological effect on the liver, kidney, and spleen tissues. Besides, no changes in the skin and hair of the rats, neither the change in the consumption of food and water, nor the change in their usual behavior were noticed during the experiment.
dc.language.isoen
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172026/RS//
dc.rightsopenAccess
dc.sourceAdvances in Materials Science and Engineering
dc.titleSubchronic Systemic Toxicity of New Endodontic Material Based on Calcium Hydroxyapatite and Calcium Silicatesen
dc.typearticleen
dc.rights.licenseBY
dcterms.abstractЈокановић, Вукоман; Прокић, Богомир Болка; Чоловић, Божана; Живковић, Славољуб; Поповић Бајић, Маријана; Томановић, Нада;
dc.rights.holder© 2018 Vukoman Jokanović et al.
dc.citation.volume2018
dc.citation.spage1
dc.citation.epage6
dc.identifier.wos000448572100001
dc.identifier.doi10.1155/2018/8493439
dc.type.versionpublishedVersion
dc.identifier.scopus2-s2.0-85062881629


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