Light controllable TiO2-Ru nanocomposite system encapsulated in phospholipid unilamellar vesicles for anti-cancer photodynamic therapy
Само за регистроване кориснике
2018
Аутори
Matijević, MilicaNešić, Maja
Stepić, Milutin
Radoičić, Marija B.
Šaponjić, Zoran
Petković, Marijana
Чланак у часопису (Објављена верзија)
,
© 2018, Springer Science+Business Media, LLC, part of Springer Nature
Метаподаци
Приказ свих података о документуАпстракт
Photodynamic therapy implies a combined use of a photosensitizing medicament and low-intensity light to cause selective damage to the target tissue—tumor. As potential medicament, we use Ru(II)(dcbpy)2Cl2complex, and in order to achieve better photosensitization properties, the Ru complex was attached to the nano carrier—TiO2nanoparticles. Additionally, this nanocomposite system was encapsulated in the phospholipid vesicles, which could be classified as small unilamellar vesicles, based on the technique of production. The complex-release tests were performed under light illumination, at pH 5, characteristic for tumor cells` interior and compared with the release pattern at pH 7, characteristic for the serum, i.e. physiological solution.
Кључне речи:
photodynamic therapy / light controlled drug release / metallo-drug deliveryИзвор:
Optical and Quantum Electronics, 2018, 50, 6, 232-Финансирање / пројекти:
- Испитивање механизма реакција комплекса јона прелазних метала са биолошки значајним молекулима (RS-MESTD-Basic Research (BR or ON)-172011)
- Утицај величине, облика и структуре наночестица на њихова својства и својства нанокомпозита (RS-MESTD-Basic Research (BR or ON)-172056)
- Фотоника микро и нано структурних материјала (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45010)
DOI: 10.1007/s11082-018-1495-z
ISSN: 0306-8919; 1572-817X
WoS: 000433079400001
Scopus: 2-s2.0-85047448688
URI
http://link.springer.com/10.1007/s11082-018-1495-zhttps://vinar.vin.bg.ac.rs/handle/123456789/7697
Колекције
Институција/група
VinčaTY - JOUR AU - Matijević, Milica AU - Nešić, Maja AU - Stepić, Milutin AU - Radoičić, Marija B. AU - Šaponjić, Zoran AU - Petković, Marijana PY - 2018 UR - http://link.springer.com/10.1007/s11082-018-1495-z UR - https://vinar.vin.bg.ac.rs/handle/123456789/7697 AB - Photodynamic therapy implies a combined use of a photosensitizing medicament and low-intensity light to cause selective damage to the target tissue—tumor. As potential medicament, we use Ru(II)(dcbpy)2Cl2complex, and in order to achieve better photosensitization properties, the Ru complex was attached to the nano carrier—TiO2nanoparticles. Additionally, this nanocomposite system was encapsulated in the phospholipid vesicles, which could be classified as small unilamellar vesicles, based on the technique of production. The complex-release tests were performed under light illumination, at pH 5, characteristic for tumor cells` interior and compared with the release pattern at pH 7, characteristic for the serum, i.e. physiological solution. T2 - Optical and Quantum Electronics T1 - Light controllable TiO2-Ru nanocomposite system encapsulated in phospholipid unilamellar vesicles for anti-cancer photodynamic therapy VL - 50 IS - 6 SP - 232 DO - 10.1007/s11082-018-1495-z ER -
@article{ author = "Matijević, Milica and Nešić, Maja and Stepić, Milutin and Radoičić, Marija B. and Šaponjić, Zoran and Petković, Marijana", year = "2018", abstract = "Photodynamic therapy implies a combined use of a photosensitizing medicament and low-intensity light to cause selective damage to the target tissue—tumor. As potential medicament, we use Ru(II)(dcbpy)2Cl2complex, and in order to achieve better photosensitization properties, the Ru complex was attached to the nano carrier—TiO2nanoparticles. Additionally, this nanocomposite system was encapsulated in the phospholipid vesicles, which could be classified as small unilamellar vesicles, based on the technique of production. The complex-release tests were performed under light illumination, at pH 5, characteristic for tumor cells` interior and compared with the release pattern at pH 7, characteristic for the serum, i.e. physiological solution.", journal = "Optical and Quantum Electronics", title = "Light controllable TiO2-Ru nanocomposite system encapsulated in phospholipid unilamellar vesicles for anti-cancer photodynamic therapy", volume = "50", number = "6", pages = "232", doi = "10.1007/s11082-018-1495-z" }
Matijević, M., Nešić, M., Stepić, M., Radoičić, M. B., Šaponjić, Z.,& Petković, M.. (2018). Light controllable TiO2-Ru nanocomposite system encapsulated in phospholipid unilamellar vesicles for anti-cancer photodynamic therapy. in Optical and Quantum Electronics, 50(6), 232. https://doi.org/10.1007/s11082-018-1495-z
Matijević M, Nešić M, Stepić M, Radoičić MB, Šaponjić Z, Petković M. Light controllable TiO2-Ru nanocomposite system encapsulated in phospholipid unilamellar vesicles for anti-cancer photodynamic therapy. in Optical and Quantum Electronics. 2018;50(6):232. doi:10.1007/s11082-018-1495-z .
Matijević, Milica, Nešić, Maja, Stepić, Milutin, Radoičić, Marija B., Šaponjić, Zoran, Petković, Marijana, "Light controllable TiO2-Ru nanocomposite system encapsulated in phospholipid unilamellar vesicles for anti-cancer photodynamic therapy" in Optical and Quantum Electronics, 50, no. 6 (2018):232, https://doi.org/10.1007/s11082-018-1495-z . .