Oxidative stress parameters changes in blood of rats treated with adriamycin and selenium
Апстракт
Most of cytostatics used in the therapy of malignant diseases express their effects either through inducing or by the direct production of reactive oxygen species (ROS), being non-specific, also affect a healthy tissue and enhance the oxidative stress. Adriamycin (ADR) injected into healthy experimental rats and examined the influence on antioxidative defense system in blood in the conditions of moderate trace element Selenium (Se) deficiency and in the optimal intake, receiving organically bound Se (dose corresponds to similar to100mug/day) for a month before treatment with ADR. In general, the diet richer in selenomethionine reduced oxidative changes caused by ADR application, analyzing 8 days after: the activities of glutathione peroxidase, catalase and superoxide dismutase, glutathione and lipid peroxidation levels in the blood.
Извор:
2003, 215-218Напомена:
- Meeting of the Society-for-Free-Radical-Research - Europe, Proceedings, Jun 26-29, 2003, Ioannina, Greece
Колекције
Институција/група
VinčaTY - CONF AU - Jozanov-Stankov, Olga AU - Demajo, Miroslav AU - Đujić, Ivana PY - 2003 UR - https://vinar.vin.bg.ac.rs/handle/123456789/6408 AB - Most of cytostatics used in the therapy of malignant diseases express their effects either through inducing or by the direct production of reactive oxygen species (ROS), being non-specific, also affect a healthy tissue and enhance the oxidative stress. Adriamycin (ADR) injected into healthy experimental rats and examined the influence on antioxidative defense system in blood in the conditions of moderate trace element Selenium (Se) deficiency and in the optimal intake, receiving organically bound Se (dose corresponds to similar to100mug/day) for a month before treatment with ADR. In general, the diet richer in selenomethionine reduced oxidative changes caused by ADR application, analyzing 8 days after: the activities of glutathione peroxidase, catalase and superoxide dismutase, glutathione and lipid peroxidation levels in the blood. T1 - Oxidative stress parameters changes in blood of rats treated with adriamycin and selenium SP - 215 EP - 218 UR - https://hdl.handle.net/21.15107/rcub_vinar_6408 ER -
@conference{ author = "Jozanov-Stankov, Olga and Demajo, Miroslav and Đujić, Ivana ", year = "2003", abstract = "Most of cytostatics used in the therapy of malignant diseases express their effects either through inducing or by the direct production of reactive oxygen species (ROS), being non-specific, also affect a healthy tissue and enhance the oxidative stress. Adriamycin (ADR) injected into healthy experimental rats and examined the influence on antioxidative defense system in blood in the conditions of moderate trace element Selenium (Se) deficiency and in the optimal intake, receiving organically bound Se (dose corresponds to similar to100mug/day) for a month before treatment with ADR. In general, the diet richer in selenomethionine reduced oxidative changes caused by ADR application, analyzing 8 days after: the activities of glutathione peroxidase, catalase and superoxide dismutase, glutathione and lipid peroxidation levels in the blood.", title = "Oxidative stress parameters changes in blood of rats treated with adriamycin and selenium", pages = "215-218", url = "https://hdl.handle.net/21.15107/rcub_vinar_6408" }
Jozanov-Stankov, O., Demajo, M.,& Đujić, I.. (2003). Oxidative stress parameters changes in blood of rats treated with adriamycin and selenium. , 215-218. https://hdl.handle.net/21.15107/rcub_vinar_6408
Jozanov-Stankov O, Demajo M, Đujić I. Oxidative stress parameters changes in blood of rats treated with adriamycin and selenium. 2003;:215-218. https://hdl.handle.net/21.15107/rcub_vinar_6408 .
Jozanov-Stankov, Olga, Demajo, Miroslav, Đujić, Ivana , "Oxidative stress parameters changes in blood of rats treated with adriamycin and selenium" (2003):215-218, https://hdl.handle.net/21.15107/rcub_vinar_6408 .