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dc.creatorPejić, Snežana
dc.creatorStojiljković, Vesna
dc.creatorTodorović, Ana
dc.creatorGavrilović, Ljubica
dc.creatorPopović, Nataša M.
dc.creatorPavlović, Ivan
dc.creatorPajović, Snežana B.
dc.identifier.issn0015-5500 (print)
dc.description.abstractCancer of the reproductive tract is an important cause of morbidity and mortality among women worldwide. In this study we evaluated the influence of diagnostic categories, age and reproductive factors on antioxidant enzymes and lipid hydroperoxides in the blood of gynaecological patients diagnosed with endometrial polyp, myoma, hyperplasia simplex, hyperplasia complex and endometrial adenocarcinoma. Multivariate regression analysis was used to assess the association of diagnosis, age, parity, abortions and abnormal uterine bleeding with the examined parameters. Diagnosis provided the best predictive model for superoxide dismutase, catalase and glutathione peroxidase activities, and also for the lipid hydroperoxide level. Abortions fitted the best predictive model for superoxide dismutase activity. A significant correlation was also found between the predictor variables themselves. This study showed that reproductive and other factors may be associated, at least partially, with antioxidant capacity and ability to defend against the oxidative damage in gynaecological patients with various diagnoses.en
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41027/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41022/RS//
dc.sourceFolia Biologicaen
dc.subjectantioxidant enzymesen
dc.subjectreproductive factorsen
dc.subjectgynaecological patientsen
dc.titleAntioxidant Status in Blood of Gynaecological Patients: Influence of Diagnosis and Reproductive Factorsen
dcterms.abstractТодоровић Aна; Павловић Иван; Пајовиц, С. Б.; Поповић Наташа; Стојиљковић Весна; Гавриловић Љубица; Пејић Снежана;

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