Inflammation as a Marker for the Prediction of Internal Carotid Artery Restenosis Following Eversion Endarterectomy-Evidence From Clinical Studies
Apstrakt
The role of inflammation is well established in the pathogenesis of atherosclerosis and an increased level of circulating inflammatory markers may predict the future risk of atherosclerosis progression and plaque rupture. C-reactive protein (CRP) identification by hypersensitive methods (high-sensitivity CRP [hsCRP]) has become a clinical and laboratory inflammation marker. Carotid endarterectomy (CEA) is a well-established procedure for carotid stenosis treatment which can reduce stroke rate. Internal carotid artery (ICA) restenosis reduction may be prevented by the anti-inflammatory effect of statins. This review considers the recent findings on the presence of hsCRP and C3 complement concentration and inflammatory plaque composition as well as their effects on ICA restenosis rate, following eversion CEA with emphasis on human studies.
Ključne reči:
high-sensitive C-reactive protein / C3 complement / internal carotid artery restenosis / carotid endarterectomyIzvor:
Angiology, 2011, 62, 7, 535-542Finansiranje / projekti:
- Karotidna bolest u Srbiji - patološka dinamika, prevencija, dijagnostika i inovativni terapijski postupci (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41002)
- Hormonska regulacija ekspresije i aktivnosti azot oksid sintaze i natrijum-kalijumove pumpe u eksperimentalnim modelima insulinske rezistencije, dijabetesa i kardiovaskularnih poremećaja (RS-MESTD-Basic Research (BR or ON)-173033)
DOI: 10.1177/0003319710398010
ISSN: 0003-3197
PubMed: 21873348
WoS: 000295729400004
Scopus: 2-s2.0-80054734433
Kolekcije
Institucija/grupa
VinčaTY - JOUR AU - Tanasković, Slobodan AU - Isenović, Esma R. AU - Radak, Đorđe J. PY - 2011 UR - https://vinar.vin.bg.ac.rs/handle/123456789/4520 AB - The role of inflammation is well established in the pathogenesis of atherosclerosis and an increased level of circulating inflammatory markers may predict the future risk of atherosclerosis progression and plaque rupture. C-reactive protein (CRP) identification by hypersensitive methods (high-sensitivity CRP [hsCRP]) has become a clinical and laboratory inflammation marker. Carotid endarterectomy (CEA) is a well-established procedure for carotid stenosis treatment which can reduce stroke rate. Internal carotid artery (ICA) restenosis reduction may be prevented by the anti-inflammatory effect of statins. This review considers the recent findings on the presence of hsCRP and C3 complement concentration and inflammatory plaque composition as well as their effects on ICA restenosis rate, following eversion CEA with emphasis on human studies. T2 - Angiology T1 - Inflammation as a Marker for the Prediction of Internal Carotid Artery Restenosis Following Eversion Endarterectomy-Evidence From Clinical Studies VL - 62 IS - 7 SP - 535 EP - 542 DO - 10.1177/0003319710398010 ER -
@article{ author = "Tanasković, Slobodan and Isenović, Esma R. and Radak, Đorđe J.", year = "2011", abstract = "The role of inflammation is well established in the pathogenesis of atherosclerosis and an increased level of circulating inflammatory markers may predict the future risk of atherosclerosis progression and plaque rupture. C-reactive protein (CRP) identification by hypersensitive methods (high-sensitivity CRP [hsCRP]) has become a clinical and laboratory inflammation marker. Carotid endarterectomy (CEA) is a well-established procedure for carotid stenosis treatment which can reduce stroke rate. Internal carotid artery (ICA) restenosis reduction may be prevented by the anti-inflammatory effect of statins. This review considers the recent findings on the presence of hsCRP and C3 complement concentration and inflammatory plaque composition as well as their effects on ICA restenosis rate, following eversion CEA with emphasis on human studies.", journal = "Angiology", title = "Inflammation as a Marker for the Prediction of Internal Carotid Artery Restenosis Following Eversion Endarterectomy-Evidence From Clinical Studies", volume = "62", number = "7", pages = "535-542", doi = "10.1177/0003319710398010" }
Tanasković, S., Isenović, E. R.,& Radak, Đ. J.. (2011). Inflammation as a Marker for the Prediction of Internal Carotid Artery Restenosis Following Eversion Endarterectomy-Evidence From Clinical Studies. in Angiology, 62(7), 535-542. https://doi.org/10.1177/0003319710398010
Tanasković S, Isenović ER, Radak ĐJ. Inflammation as a Marker for the Prediction of Internal Carotid Artery Restenosis Following Eversion Endarterectomy-Evidence From Clinical Studies. in Angiology. 2011;62(7):535-542. doi:10.1177/0003319710398010 .
Tanasković, Slobodan, Isenović, Esma R., Radak, Đorđe J., "Inflammation as a Marker for the Prediction of Internal Carotid Artery Restenosis Following Eversion Endarterectomy-Evidence From Clinical Studies" in Angiology, 62, no. 7 (2011):535-542, https://doi.org/10.1177/0003319710398010 . .