The influence of silicon substitution on the properties of spherical- and whisker-like biphasic alpha-calcium-phosphate/hydroxyapatite particles
Нема приказа
Аутори
Jokić, Bojan M.Mitrić, Miodrag
Popović, Maja
Sima, L.
Petrescu, S. M.
Petrović, R.
Janaćković, Đorđe T.
Чланак у часопису
Метаподаци
Приказ свих података о документуАпстракт
In this work, the influence of the morphology of hydroxyapatite particles on silicon substitution through hydrothermal synthesis performed under the same conditions was investigated. Spherical- and whisker-like hydroxyapatite particles were obtained starting from calcium-nitrate, sodium dihydrogen phosphate, disodium-ethylenediaminetetraacetic acid and urea (used only for the synthesis of whisker-like particles) dissolved in aqueous solutions. Silicon was introduced into the solution using tetraethylorthosilicate. X-ray diffraction, infrared spectroscopy, scanning electron microscopy, energy-dispersive X-ray spectroscopy and transmission electron microscopy indicate that silicon doping induce different phase compositions and bioactivity of spherical- and whisker-like hydroxyapatite particles obtained under the same hydrothermal conditions. Silicon-substituted, spherical hydroxyapatites particles showed greater phase transformation to silicon-substituted alpha- calcium-phosphate compare...d with whiskers-like hydroxyapatite particles synthesized with the same amount of added silicon. Metabolic activity assay performed with SaOs2 osteosarcoma cells showed better biocompatibility of annealed biphasic spherical-like particles compared with annealed whiskerlike particles while dried spherical-like particles induce high cytotoxicity effect.
Извор:
Journal of Materials Science: Materials in Medicine, 2011, 22, 10, 2175-2185Финансирање / пројекти:
- Ministry of Science and Technological Development [III45019]
DOI: 10.1007/s10856-011-4412-6
ISSN: 0957-4530
PubMed: 21823030
WoS: 000295712600004
Scopus: 2-s2.0-84855166904
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Институција/група
VinčaTY - JOUR AU - Jokić, Bojan M. AU - Mitrić, Miodrag AU - Popović, Maja AU - Sima, L. AU - Petrescu, S. M. AU - Petrović, R. AU - Janaćković, Đorđe T. PY - 2011 UR - https://vinar.vin.bg.ac.rs/handle/123456789/4518 AB - In this work, the influence of the morphology of hydroxyapatite particles on silicon substitution through hydrothermal synthesis performed under the same conditions was investigated. Spherical- and whisker-like hydroxyapatite particles were obtained starting from calcium-nitrate, sodium dihydrogen phosphate, disodium-ethylenediaminetetraacetic acid and urea (used only for the synthesis of whisker-like particles) dissolved in aqueous solutions. Silicon was introduced into the solution using tetraethylorthosilicate. X-ray diffraction, infrared spectroscopy, scanning electron microscopy, energy-dispersive X-ray spectroscopy and transmission electron microscopy indicate that silicon doping induce different phase compositions and bioactivity of spherical- and whisker-like hydroxyapatite particles obtained under the same hydrothermal conditions. Silicon-substituted, spherical hydroxyapatites particles showed greater phase transformation to silicon-substituted alpha- calcium-phosphate compared with whiskers-like hydroxyapatite particles synthesized with the same amount of added silicon. Metabolic activity assay performed with SaOs2 osteosarcoma cells showed better biocompatibility of annealed biphasic spherical-like particles compared with annealed whiskerlike particles while dried spherical-like particles induce high cytotoxicity effect. T2 - Journal of Materials Science: Materials in Medicine T1 - The influence of silicon substitution on the properties of spherical- and whisker-like biphasic alpha-calcium-phosphate/hydroxyapatite particles VL - 22 IS - 10 SP - 2175 EP - 2185 DO - 10.1007/s10856-011-4412-6 ER -
@article{ author = "Jokić, Bojan M. and Mitrić, Miodrag and Popović, Maja and Sima, L. and Petrescu, S. M. and Petrović, R. and Janaćković, Đorđe T.", year = "2011", abstract = "In this work, the influence of the morphology of hydroxyapatite particles on silicon substitution through hydrothermal synthesis performed under the same conditions was investigated. Spherical- and whisker-like hydroxyapatite particles were obtained starting from calcium-nitrate, sodium dihydrogen phosphate, disodium-ethylenediaminetetraacetic acid and urea (used only for the synthesis of whisker-like particles) dissolved in aqueous solutions. Silicon was introduced into the solution using tetraethylorthosilicate. X-ray diffraction, infrared spectroscopy, scanning electron microscopy, energy-dispersive X-ray spectroscopy and transmission electron microscopy indicate that silicon doping induce different phase compositions and bioactivity of spherical- and whisker-like hydroxyapatite particles obtained under the same hydrothermal conditions. Silicon-substituted, spherical hydroxyapatites particles showed greater phase transformation to silicon-substituted alpha- calcium-phosphate compared with whiskers-like hydroxyapatite particles synthesized with the same amount of added silicon. Metabolic activity assay performed with SaOs2 osteosarcoma cells showed better biocompatibility of annealed biphasic spherical-like particles compared with annealed whiskerlike particles while dried spherical-like particles induce high cytotoxicity effect.", journal = "Journal of Materials Science: Materials in Medicine", title = "The influence of silicon substitution on the properties of spherical- and whisker-like biphasic alpha-calcium-phosphate/hydroxyapatite particles", volume = "22", number = "10", pages = "2175-2185", doi = "10.1007/s10856-011-4412-6" }
Jokić, B. M., Mitrić, M., Popović, M., Sima, L., Petrescu, S. M., Petrović, R.,& Janaćković, Đ. T.. (2011). The influence of silicon substitution on the properties of spherical- and whisker-like biphasic alpha-calcium-phosphate/hydroxyapatite particles. in Journal of Materials Science: Materials in Medicine, 22(10), 2175-2185. https://doi.org/10.1007/s10856-011-4412-6
Jokić BM, Mitrić M, Popović M, Sima L, Petrescu SM, Petrović R, Janaćković ĐT. The influence of silicon substitution on the properties of spherical- and whisker-like biphasic alpha-calcium-phosphate/hydroxyapatite particles. in Journal of Materials Science: Materials in Medicine. 2011;22(10):2175-2185. doi:10.1007/s10856-011-4412-6 .
Jokić, Bojan M., Mitrić, Miodrag, Popović, Maja, Sima, L., Petrescu, S. M., Petrović, R., Janaćković, Đorđe T., "The influence of silicon substitution on the properties of spherical- and whisker-like biphasic alpha-calcium-phosphate/hydroxyapatite particles" in Journal of Materials Science: Materials in Medicine, 22, no. 10 (2011):2175-2185, https://doi.org/10.1007/s10856-011-4412-6 . .