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Apolipoprotein B gene polymorphisms in patients from Serbia with ischemic cerebrovascular disease
dc.creator | Stanković, Aleksandra | |
dc.creator | Stanković, Sanja | |
dc.creator | Jovanovic-Markovic, Zagorka | |
dc.creator | Živković, Maja | |
dc.creator | Đurić, Tamara | |
dc.creator | Glišić, Sanja | |
dc.creator | Alavantić, Dragan | |
dc.date.accessioned | 2018-03-01T20:23:15Z | |
dc.date.available | 2018-03-01T20:23:15Z | |
dc.date.issued | 2007 | |
dc.identifier.issn | 0354-4664 | |
dc.identifier.uri | https://vinar.vin.bg.ac.rs/handle/123456789/3419 | |
dc.description.abstract | The plasma concentration of apoB has recently been reported to be the best lipid predictor of coronary heart disease. The possible associations of genetic markers in the apolipoprotein B gene (Xbal, EcoRI, MspI, Ins/Del, and 4311 A/G polymorphisms) were evaluated in patients with ischemic cerebrovascular disease (ICVD) and controls of equivalent BMI. The odds ratio for ICVD in the X+X+ genotype was 2.22, 95% CI 1.24-3.96 (P LT 0.05), while that for ICVD in the Ins/Ins genotype was 2.82, 95% CI 1.57-5.06 (P LT 0.05). The patients had significantly higher frequency of the 4311 A allele compared to the controls (P LT 0.01). Our results support the assumption that apoB gene polymorphisms may contribute to the extent of cerebrovascular disease risk. | en |
dc.relation | info:eu-repo/grantAgreement/MESTD/MPN2006-2010/145023/RS// | |
dc.rights | openAccess | en |
dc.source | Archives of Biological Sciences | en |
dc.subject | ApoB | en |
dc.subject | ischemic cerebrovascular disease | en |
dc.subject | gene | en |
dc.subject | polymorphism | en |
dc.subject | human population | en |
dc.subject | Serbia | en |
dc.title | Apolipoprotein B gene polymorphisms in patients from Serbia with ischemic cerebrovascular disease | en |
dc.type | article | en |
dcterms.abstract | Станковиц, Сања; Јовановиц-Марковиц, Загорка; Станковић Aлександра; Живковић Маја; Ђурић Тамара; Глишић Сања; Aлавантић Драган; | |
dc.citation.volume | 59 | |
dc.citation.issue | 4 | |
dc.citation.spage | 303 | |
dc.citation.epage | 309 | |
dc.identifier.wos | 000254920100008 | |
dc.identifier.doi | 10.2298/ABS0704303S | |
dc.identifier.fulltext | https://vinar.vin.bg.ac.rs//bitstream/id/12462/3415.pdf |
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080 - Laboratorija za radiobiologiju i molekularnu genetiku
Department of Radiobiology and Molecular Genetics