Two-step hydrothermal synthesis of nano hydroxyapatite particles and their characterization
Apstrakt
In this paper, the synthesis and characterization of calcium hydroxyapatite particles, stabilized with poly(ethylene-vinyl acetate) / poly(ethylene-vinyl versatate) (PEVA/PEVV) are presented. The particles were synthesized by two-step hydrothermal method using PEVA/PEVV as a surface-active substance. The structure and crystallinity of the obtained powder were investigated by X-ray diffraction, TEM and HRTEM. The phase identification of hydroxyapatite stabilized with PEVA/PEVV was done by FTIR, while the surface morphology, as well as the size and shape of particles were studied by TEM and AFM. Finally, using MTT and LDH release assays to assess mitochondrial activity and cell membrane integrity, it was confirmed that so synthesized hydroxyapatite powder was not toxic to L929 cells.
Ključne reči:
Hydrothermal synthesis / Hydroxyapatite / Ethylene-vinyl acetate/versatate copolymer / TEM / HRTEMIzvor:
Journal of Optoelectronics and Advanced Materials, 2014, 16, 11-12, 1356-1360Finansiranje / projekti:
- Hemijsko i strukturno dizajniranje nanomaterijala za primenu u medicini i inženjerstvu tkiva (RS-MESTD-Basic Research (BR or ON)-172026)
Kolekcije
Institucija/grupa
VinčaTY - JOUR AU - Čolović, Božana M. AU - Marković, D. AU - Petrović, Milica S. AU - Jokanović, Vukoman R. PY - 2014 UR - https://vinar.vin.bg.ac.rs/handle/123456789/339 AB - In this paper, the synthesis and characterization of calcium hydroxyapatite particles, stabilized with poly(ethylene-vinyl acetate) / poly(ethylene-vinyl versatate) (PEVA/PEVV) are presented. The particles were synthesized by two-step hydrothermal method using PEVA/PEVV as a surface-active substance. The structure and crystallinity of the obtained powder were investigated by X-ray diffraction, TEM and HRTEM. The phase identification of hydroxyapatite stabilized with PEVA/PEVV was done by FTIR, while the surface morphology, as well as the size and shape of particles were studied by TEM and AFM. Finally, using MTT and LDH release assays to assess mitochondrial activity and cell membrane integrity, it was confirmed that so synthesized hydroxyapatite powder was not toxic to L929 cells. T2 - Journal of Optoelectronics and Advanced Materials T1 - Two-step hydrothermal synthesis of nano hydroxyapatite particles and their characterization VL - 16 IS - 11-12 SP - 1356 EP - 1360 UR - https://hdl.handle.net/21.15107/rcub_vinar_339 ER -
@article{ author = "Čolović, Božana M. and Marković, D. and Petrović, Milica S. and Jokanović, Vukoman R.", year = "2014", abstract = "In this paper, the synthesis and characterization of calcium hydroxyapatite particles, stabilized with poly(ethylene-vinyl acetate) / poly(ethylene-vinyl versatate) (PEVA/PEVV) are presented. The particles were synthesized by two-step hydrothermal method using PEVA/PEVV as a surface-active substance. The structure and crystallinity of the obtained powder were investigated by X-ray diffraction, TEM and HRTEM. The phase identification of hydroxyapatite stabilized with PEVA/PEVV was done by FTIR, while the surface morphology, as well as the size and shape of particles were studied by TEM and AFM. Finally, using MTT and LDH release assays to assess mitochondrial activity and cell membrane integrity, it was confirmed that so synthesized hydroxyapatite powder was not toxic to L929 cells.", journal = "Journal of Optoelectronics and Advanced Materials", title = "Two-step hydrothermal synthesis of nano hydroxyapatite particles and their characterization", volume = "16", number = "11-12", pages = "1356-1360", url = "https://hdl.handle.net/21.15107/rcub_vinar_339" }
Čolović, B. M., Marković, D., Petrović, M. S.,& Jokanović, V. R.. (2014). Two-step hydrothermal synthesis of nano hydroxyapatite particles and their characterization. in Journal of Optoelectronics and Advanced Materials, 16(11-12), 1356-1360. https://hdl.handle.net/21.15107/rcub_vinar_339
Čolović BM, Marković D, Petrović MS, Jokanović VR. Two-step hydrothermal synthesis of nano hydroxyapatite particles and their characterization. in Journal of Optoelectronics and Advanced Materials. 2014;16(11-12):1356-1360. https://hdl.handle.net/21.15107/rcub_vinar_339 .
Čolović, Božana M., Marković, D., Petrović, Milica S., Jokanović, Vukoman R., "Two-step hydrothermal synthesis of nano hydroxyapatite particles and their characterization" in Journal of Optoelectronics and Advanced Materials, 16, no. 11-12 (2014):1356-1360, https://hdl.handle.net/21.15107/rcub_vinar_339 .