Nonlinear properties of cardiac rhythm and respiratory signal under paced breathing in young and middle-aged healthy subjects
Апстракт
We examined the effects of gender and age in young and middle-aged subjects on the level of cardiorespiratory interaction by analyzing properties of cardiac, respiratory and cardiac-respiratory regulatory mechanisms under paced breathing. In 56 healthy subjects, ECG (RR interval) and respiratory signal were simultaneously acquired in supine position at paced (0.1-0.45 Hz, steps of 0.05 Hz) and spontaneous breathing. The participants were divided into gender matched group of young adults (19-25 years old) and middle-aged adults (35-44 years old). Power spectral analysis was applied on RR interval time series and spectral components in very low frequency (VLF), low frequency (LF) and high frequency (HF) ranges were computed. We also calculated Sample entropy of RR interval series (SampEnRR), respiratory series (SampEnResp), and their cross-sample entropy (cross-SampEn). Under paced breathing, reduction of all spectral powers with age (p LT 0.05) is not gender dependent but reduction of s...ome entropy measures is; SampEnRR and SampEnResp were lower only in men (p LT 0.05). In the middle-aged subjects, effect of gender on spectral measures is significant; males had lower HF (p LT 0.05). Pattern of dependencies of SampEn and cross-SampEn on paced breathing frequency were significantly different in men (young vs. middle-aged, p = 0.001 and p = 0.037) and in middle-aged subjects (females vs. males, p = 0.011 and p = 0.008). In middle-aged males, lower entropy measures indicated reduced and less complex partial cardiac and respiratory control, and central cardio-respiratory control. In conclusion, in healthy middle-aged subjects changes in cardio-respiratory coupling are detectable only in males. (C) 2014 IPEM. Published by Elsevier Ltd. All rights reserved.
Кључне речи:
Aging / Sex difference / Cardio-respiratory coupling / Entropy / Heart rate variabilityИзвор:
Medical Engineering and Physics, 2014, 36, 12, 1577-1584Финансирање / пројекти:
- Развој технологије производње црвеног вина и дијететских производа из вина богатих биолошки активним полифенолима са кардиопротективним дејствима (RS-MESTD-Technological Development (TD or TR)-31020)
- Неуробиологија спавања у старењу и болести - електроенцефалографски маркери и моделирање у процени поремећаја (RS-MESTD-Basic Research (BR or ON)-173022)
- Интегрална студија идентификације регионалних генетских фактора ризика и фактора ризика животне средине за масовне незаразне болести хумане популације у Србији - INGEMA_S (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41028)
DOI: 10.1016/j.medengphy.2014.08.007
ISSN: 1350-4533
PubMed: 25199589
WoS: 000347502000003
Scopus: 2-s2.0-84922784106
Колекције
Институција/група
VinčaTY - JOUR AU - Kapidžić, Ana AU - Platiša, Mirjana M. AU - Bojić, Tijana AU - Kalauzi, Aleksandar PY - 2014 UR - https://vinar.vin.bg.ac.rs/handle/123456789/338 AB - We examined the effects of gender and age in young and middle-aged subjects on the level of cardiorespiratory interaction by analyzing properties of cardiac, respiratory and cardiac-respiratory regulatory mechanisms under paced breathing. In 56 healthy subjects, ECG (RR interval) and respiratory signal were simultaneously acquired in supine position at paced (0.1-0.45 Hz, steps of 0.05 Hz) and spontaneous breathing. The participants were divided into gender matched group of young adults (19-25 years old) and middle-aged adults (35-44 years old). Power spectral analysis was applied on RR interval time series and spectral components in very low frequency (VLF), low frequency (LF) and high frequency (HF) ranges were computed. We also calculated Sample entropy of RR interval series (SampEnRR), respiratory series (SampEnResp), and their cross-sample entropy (cross-SampEn). Under paced breathing, reduction of all spectral powers with age (p LT 0.05) is not gender dependent but reduction of some entropy measures is; SampEnRR and SampEnResp were lower only in men (p LT 0.05). In the middle-aged subjects, effect of gender on spectral measures is significant; males had lower HF (p LT 0.05). Pattern of dependencies of SampEn and cross-SampEn on paced breathing frequency were significantly different in men (young vs. middle-aged, p = 0.001 and p = 0.037) and in middle-aged subjects (females vs. males, p = 0.011 and p = 0.008). In middle-aged males, lower entropy measures indicated reduced and less complex partial cardiac and respiratory control, and central cardio-respiratory control. In conclusion, in healthy middle-aged subjects changes in cardio-respiratory coupling are detectable only in males. (C) 2014 IPEM. Published by Elsevier Ltd. All rights reserved. T2 - Medical Engineering and Physics T1 - Nonlinear properties of cardiac rhythm and respiratory signal under paced breathing in young and middle-aged healthy subjects VL - 36 IS - 12 SP - 1577 EP - 1584 DO - 10.1016/j.medengphy.2014.08.007 ER -
@article{ author = "Kapidžić, Ana and Platiša, Mirjana M. and Bojić, Tijana and Kalauzi, Aleksandar", year = "2014", abstract = "We examined the effects of gender and age in young and middle-aged subjects on the level of cardiorespiratory interaction by analyzing properties of cardiac, respiratory and cardiac-respiratory regulatory mechanisms under paced breathing. In 56 healthy subjects, ECG (RR interval) and respiratory signal were simultaneously acquired in supine position at paced (0.1-0.45 Hz, steps of 0.05 Hz) and spontaneous breathing. The participants were divided into gender matched group of young adults (19-25 years old) and middle-aged adults (35-44 years old). Power spectral analysis was applied on RR interval time series and spectral components in very low frequency (VLF), low frequency (LF) and high frequency (HF) ranges were computed. We also calculated Sample entropy of RR interval series (SampEnRR), respiratory series (SampEnResp), and their cross-sample entropy (cross-SampEn). Under paced breathing, reduction of all spectral powers with age (p LT 0.05) is not gender dependent but reduction of some entropy measures is; SampEnRR and SampEnResp were lower only in men (p LT 0.05). In the middle-aged subjects, effect of gender on spectral measures is significant; males had lower HF (p LT 0.05). Pattern of dependencies of SampEn and cross-SampEn on paced breathing frequency were significantly different in men (young vs. middle-aged, p = 0.001 and p = 0.037) and in middle-aged subjects (females vs. males, p = 0.011 and p = 0.008). In middle-aged males, lower entropy measures indicated reduced and less complex partial cardiac and respiratory control, and central cardio-respiratory control. In conclusion, in healthy middle-aged subjects changes in cardio-respiratory coupling are detectable only in males. (C) 2014 IPEM. Published by Elsevier Ltd. All rights reserved.", journal = "Medical Engineering and Physics", title = "Nonlinear properties of cardiac rhythm and respiratory signal under paced breathing in young and middle-aged healthy subjects", volume = "36", number = "12", pages = "1577-1584", doi = "10.1016/j.medengphy.2014.08.007" }
Kapidžić, A., Platiša, M. M., Bojić, T.,& Kalauzi, A.. (2014). Nonlinear properties of cardiac rhythm and respiratory signal under paced breathing in young and middle-aged healthy subjects. in Medical Engineering and Physics, 36(12), 1577-1584. https://doi.org/10.1016/j.medengphy.2014.08.007
Kapidžić A, Platiša MM, Bojić T, Kalauzi A. Nonlinear properties of cardiac rhythm and respiratory signal under paced breathing in young and middle-aged healthy subjects. in Medical Engineering and Physics. 2014;36(12):1577-1584. doi:10.1016/j.medengphy.2014.08.007 .
Kapidžić, Ana, Platiša, Mirjana M., Bojić, Tijana, Kalauzi, Aleksandar, "Nonlinear properties of cardiac rhythm and respiratory signal under paced breathing in young and middle-aged healthy subjects" in Medical Engineering and Physics, 36, no. 12 (2014):1577-1584, https://doi.org/10.1016/j.medengphy.2014.08.007 . .