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QUEST-RA: quantitative clinical assessment of patients with rheumatoid arthritis seen in standard rheumatology care in 15 countries
dc.creator | Sokka, Tuulikki | |
dc.creator | Kautiainen, Hannu | |
dc.creator | Toloza, Sergio | |
dc.creator | Makinen, Heidi | |
dc.creator | Verstappen, Suzan M. M. | |
dc.creator | Hetland, Merete Lund | |
dc.creator | Naranjo, Antonio | |
dc.creator | Baecklund, Eva | |
dc.creator | Herborn, Gertraud | |
dc.creator | Rau, Rolf | |
dc.creator | Cazzato, Massimiliano | |
dc.creator | Gossec, Laure | |
dc.creator | Skakic, Vlado | |
dc.creator | Gogus, Feride | |
dc.creator | Sierakowski, Stanislaw | |
dc.creator | Bresnihan, Barry | |
dc.creator | Taylor, Peter | |
dc.creator | McClinton, Catherine | |
dc.creator | Pincus, Theodore | |
dc.creator | the QUEST-RA Grp | |
dc.date.accessioned | 2018-03-01T20:13:23Z | |
dc.date.available | 2018-03-01T20:13:23Z | |
dc.date.issued | 2007 | |
dc.identifier.issn | 0003-4967 | |
dc.identifier.uri | https://vinar.vin.bg.ac.rs/handle/123456789/3303 | |
dc.description.abstract | Objective: To conduct a cross- sectional review of non- selected consecutive outpatients with rheumatoid arthritis ( RA) as part of standard clinical care in 15 countries for an overview of the characteristics of patients with RA. Methods: The review included current disease activity using data from clinical assessment and a patient self-report questionnaire, which was translated into each language. Data on demographic, disease and treatment- related variables were collected and analysed using descriptive statistics. Variation in disease activity on DAS28 ( disease activity score on 28- joint count) within and between countries was graphically analysed. A median regression model was applied to analyse differences in disease activity between countries. Results: Between January 2005 and October 2006, the QUEST- RA ( Quantitative Patient Questionnaires in Standard Monitoring of Patients with Rheumatoid Arthritis) project included 4363 patients from 48 sites in 15 countries; 78% were female,. GT 90% Caucasian, mean age was 57 years and mean disease duration was 11.5 years. More than 80% of patients had been treated with methotrexate in all but three countries. Overall, patients had an active disease with a median DAS28 of 4.0, with a significant variation between countries ( p LT 0.001). Among 42 sites with GT 50 patients included, low disease activity of DAS28 LT = 3.2 was found in the majority of patients in seven sites in five countries; in eight sites in five other countries, GT 50% of patients had high disease activity of DAS28 GT 5.1. Conclusions: This international multicentre cross- sectional database provides an overview of clinical status and treatments of patients with RA in standard clinical care in 2005 - 6 including countries that are infrequently involved in clinical research projects. | en |
dc.rights | openAccess | en |
dc.source | Annals of the Rheumatic Diseases | en |
dc.title | QUEST-RA: quantitative clinical assessment of patients with rheumatoid arthritis seen in standard rheumatology care in 15 countries | en |
dc.type | article | en |
dcterms.abstract | Каутиаинен, Ханну; Толоза, Сергио; Макинен, Хеиди; Верстаппен, Сузан М. М.; Хетланд, Мерете Лунд; Нарањо, Aнтонио; Баецклунд, Ева; Херборн, Гертрауд; Рау, Ролф; Цаззато, Массимилиано; Госсец, Лауре; Скакиц, Владо; Гогус, Фериде; Сиеракоwски, Станислаw; Бреснихан, Баррy; Таyлор, Петер; МцЦлинтон, Цатхерине; Пинцус, Тхеодоре; тхе QУЕСТ-РA Грп; Сокка, Тууликки; | |
dc.citation.volume | 66 | |
dc.citation.issue | 11 | |
dc.citation.spage | 1491 | |
dc.citation.epage | 1496 | |
dc.identifier.wos | 000250147900015 | |
dc.identifier.doi | 10.1136/ard.2006.069252 | |
dc.citation.rank | M21a | |
dc.identifier.pmid | 17412740 | |
dc.identifier.scopus | 2-s2.0-34347388745 |
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