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Matrix metalloproteinase-9-1562 C/T gene polymorphism in Serbian patients with multiple sclerosis
dc.creator | Živković, Maja | |
dc.creator | Đurić, Tamara | |
dc.creator | Dinčić, Evica | |
dc.creator | Raičević, Ranko | |
dc.creator | Alavantić, Dragan | |
dc.creator | Stanković, Aleksandra | |
dc.date.accessioned | 2018-03-01T20:13:03Z | |
dc.date.available | 2018-03-01T20:13:03Z | |
dc.date.issued | 2007 | |
dc.identifier.issn | 0165-5728 | |
dc.identifier.uri | https://vinar.vin.bg.ac.rs/handle/123456789/3299 | |
dc.description.abstract | Matrix metalloproteinase-9 (MMP-9) is suggested to play a role in MS by mediating T cell migration across subendothelial basement membrane and by contribution to myelin breakdown. We studied the association of MMP-9 -1562 C/T gene polymorphisms with MS susceptibility and severity in 187 patients from Serbia. The significant decrease in T allele carriership (p=0.01), was found in female NIS patients, In addition, a trend toward lower MSSS in T allele carriers was noticed (CC, mean 5.7 +/- 2.5 vs. CT+TT, mean 4.9 +/- 2.5). Further studies in different populations are needed to resolve the potential influence of MMP-9 gene polymorphism on MS. (C) 2007 Elsevier B.V. All rights reserved. | en |
dc.relation | info:eu-repo/grantAgreement/MESTD/MPN2006-2010/145023/RS// | |
dc.rights | restrictedAccess | en |
dc.source | Journal of Neuroimmunology | en |
dc.subject | MMP-9 | en |
dc.subject | gene | en |
dc.subject | polymorphism | en |
dc.subject | multiple sclerosis | en |
dc.title | Matrix metalloproteinase-9-1562 C/T gene polymorphism in Serbian patients with multiple sclerosis | en |
dc.type | article | en |
dc.rights.license | ARR | |
dcterms.abstract | Динциц, Евица; Раицевиц, Ранко; Живковић Маја; Ђурић Тамара; Aлавантић Драган; Станковић Aлександра; | |
dc.citation.volume | 189 | |
dc.citation.issue | 1-2 | |
dc.citation.spage | 147 | |
dc.citation.epage | 150 | |
dc.identifier.wos | 000250068800019 | |
dc.identifier.doi | 10.1016/j.jneuroim.2007.06.022 | |
dc.citation.rank | M22 | |
dc.identifier.pmid | 17655938 | |
dc.type.version | publishedVersion | |
dc.identifier.scopus | 2-s2.0-34548542224 |