High Sensitivity C-reactive Protein and Cardiovascular Risk Prediction
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Trpković, AndrejaStanimirović, Julijana
Resanović, Ivana
Otasevic, Petar
Jevremovic, Danimir
Radak, Đorđe J.
Isenović, Esma R.
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It is now recognized that inflammatory processes regulate all stages of atherosclerosis, from disease initiation to thrombotic complications. C-reactive protein (CRP) is a plasmatic protein used as a general marker of inflammation. The high sensitivity C-reactive protein (hsCRP) refers to the measurement of CRP in blood samples using assays with sufficient sensitivity to quantify low (baseline) levels of this biomarker. Low-grade chronic inflammatory processes are linked to atherosclerosis and may be screened with the use of hsCRP, thus providing additional information in cardiovascular risk prediction. This review elaborates the role of CRP in atherogenesis and the value of hsCRP as a biomarker in cardiovascular risk prediction in both primary and secondary prevention setting.
Keywords:
Atherogenesis / biomarker / cardiovascular disease / C-reactive protein / high sensitivity C-reactive protein / inflammation / preventionSource:
Current Pharmaceutical Analysis, 2015, 11, 1, 60-65Funding / projects:
- Hormonal regulation of expression and activity of the nitric oxide synthase and sodium-potassium pump in experimental models of insulin resistance, diabetes and cardiovascular disorders (RS-MESTD-Basic Research (BR or ON)-173033)
DOI: 10.2174/1573412910666140822003911
ISSN: 1573-4129
WoS: 000346830400010
Scopus: 2-s2.0-84920531555
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VinčaTY - JOUR AU - Trpković, Andreja AU - Stanimirović, Julijana AU - Resanović, Ivana AU - Otasevic, Petar AU - Jevremovic, Danimir AU - Radak, Đorđe J. AU - Isenović, Esma R. PY - 2015 UR - https://vinar.vin.bg.ac.rs/handle/123456789/312 AB - It is now recognized that inflammatory processes regulate all stages of atherosclerosis, from disease initiation to thrombotic complications. C-reactive protein (CRP) is a plasmatic protein used as a general marker of inflammation. The high sensitivity C-reactive protein (hsCRP) refers to the measurement of CRP in blood samples using assays with sufficient sensitivity to quantify low (baseline) levels of this biomarker. Low-grade chronic inflammatory processes are linked to atherosclerosis and may be screened with the use of hsCRP, thus providing additional information in cardiovascular risk prediction. This review elaborates the role of CRP in atherogenesis and the value of hsCRP as a biomarker in cardiovascular risk prediction in both primary and secondary prevention setting. T2 - Current Pharmaceutical Analysis T1 - High Sensitivity C-reactive Protein and Cardiovascular Risk Prediction VL - 11 IS - 1 SP - 60 EP - 65 DO - 10.2174/1573412910666140822003911 ER -
@article{ author = "Trpković, Andreja and Stanimirović, Julijana and Resanović, Ivana and Otasevic, Petar and Jevremovic, Danimir and Radak, Đorđe J. and Isenović, Esma R.", year = "2015", abstract = "It is now recognized that inflammatory processes regulate all stages of atherosclerosis, from disease initiation to thrombotic complications. C-reactive protein (CRP) is a plasmatic protein used as a general marker of inflammation. The high sensitivity C-reactive protein (hsCRP) refers to the measurement of CRP in blood samples using assays with sufficient sensitivity to quantify low (baseline) levels of this biomarker. Low-grade chronic inflammatory processes are linked to atherosclerosis and may be screened with the use of hsCRP, thus providing additional information in cardiovascular risk prediction. This review elaborates the role of CRP in atherogenesis and the value of hsCRP as a biomarker in cardiovascular risk prediction in both primary and secondary prevention setting.", journal = "Current Pharmaceutical Analysis", title = "High Sensitivity C-reactive Protein and Cardiovascular Risk Prediction", volume = "11", number = "1", pages = "60-65", doi = "10.2174/1573412910666140822003911" }
Trpković, A., Stanimirović, J., Resanović, I., Otasevic, P., Jevremovic, D., Radak, Đ. J.,& Isenović, E. R.. (2015). High Sensitivity C-reactive Protein and Cardiovascular Risk Prediction. in Current Pharmaceutical Analysis, 11(1), 60-65. https://doi.org/10.2174/1573412910666140822003911
Trpković A, Stanimirović J, Resanović I, Otasevic P, Jevremovic D, Radak ĐJ, Isenović ER. High Sensitivity C-reactive Protein and Cardiovascular Risk Prediction. in Current Pharmaceutical Analysis. 2015;11(1):60-65. doi:10.2174/1573412910666140822003911 .
Trpković, Andreja, Stanimirović, Julijana, Resanović, Ivana, Otasevic, Petar, Jevremovic, Danimir, Radak, Đorđe J., Isenović, Esma R., "High Sensitivity C-reactive Protein and Cardiovascular Risk Prediction" in Current Pharmaceutical Analysis, 11, no. 1 (2015):60-65, https://doi.org/10.2174/1573412910666140822003911 . .