Приказ основних података о документу

dc.creatorPajović, Snežana B.
dc.creatorPejić, Snežana
dc.creatorStojiljković, Vesna
dc.creatorGavrilović, Ljubica
dc.creatorDronjak, Slađana
dc.creatorKanazir, Dušan T.
dc.date.accessioned2018-03-01T19:53:57Z
dc.date.available2018-03-01T19:53:57Z
dc.date.issued2006
dc.identifier.issn0862-8408
dc.identifier.urihttps://vinar.vin.bg.ac.rs/handle/123456789/3075
dc.description.abstractThe study deals with activity of three antioxidant enzymes, copper, zinc-superoxide dismutase (CuZnSOD), manganese superoxide dismutase (MnSOD), catalase (CAT) in hippocampus of rats, following the exposure to single chronic (individual housing or forced swimming) and acute (immobilization or cold) stress, as well as to combined chronic/acute stress. In addition, plasma noradrenaline (NA) and adrenaline (A) concentrations were measured in the same stress conditions, because their autooxidation can add to the oxidative stress. We observed that i) long-term social isolation and repeated forced swimming had minor effects on plasma catecholamines, but in the long-term pretreated groups, acute stressors caused profound elevation NA and A levels, ii) chronic stressors activate antioxidant enzymes, iii) acute stressors decrease catalase activity, their effects on CuZnSOD appear to be stressor-dependent, whereas MnSOD is not affected by acute stressors, and iv) pre-exposure to chronic stress affects the antioxidant-related effects of acute stressors, but this effect depends to a large extent on the type of the chronic stressor. Based on both metabolic and neuroendocrine data, long-term isolation appears to be a robust psychological stressor and to induce a priming effect specifically on the CuZnSOD and CAT activity.en
dc.rightsrestrictedAccessen
dc.sourcePhysiological Researchen
dc.subjectstressen
dc.subjecthippocampusen
dc.subjectantioxidant enzymesen
dc.subjectcatecholaminesen
dc.titleAlterations in hippocampal antioxidant enzyme activities and sympatho-adrenomedullary system of rats in response to different stress modelsen
dc.typearticleen
dcterms.abstractПајовиц, С. Б.; Каназир, Д. Т.; Пејић Снежана; Стојиљковић Весна; Гавриловић Љубица; Дроњак Слађана;
dc.citation.volume55
dc.citation.issue4
dc.citation.spage453
dc.citation.epage460
dc.identifier.wos000240124800013
dc.citation.rankM22
dc.identifier.pmid16238459
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_vinar_3075


Документи

ДатотекеВеличинаФорматПреглед

Уз овај запис нема датотека.

Овај документ се појављује у следећим колекцијама

Приказ основних података о документу