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The role of passive immunization in HIV-positive patients - A case report
dc.creator | Veljković, Veljko | |
dc.creator | Metlaš, Radmila | |
dc.creator | Jevtović, D. | |
dc.creator | Stringer, WW | |
dc.date.accessioned | 2018-03-01T18:59:58Z | |
dc.date.available | 2018-03-01T18:59:58Z | |
dc.date.issued | 2001 | |
dc.identifier.issn | 0012-3692 | |
dc.identifier.uri | https://vinar.vin.bg.ac.rs/handle/123456789/2448 | |
dc.description.abstract | An HIV positive patient presented with pulmonary tuberculosis as her AIDS-defining diagnosis in 1993 and was effectively treated with 12 months of standard antituberculosis medications (isoniazide, rifampin, and pyrazinamide for 2 months). She received zidovudine for 6 weeks at the time of her diagnosis; however, because of patient preference, she has not received subsequent standard HIV medications (7 years). Her CD4 count at the time of diagnosis (1993) was 297/muL. Monthly passive immunotherapy was administered (fresh frozen plasma from HIV-negative blood donors with a significant titer for the anti-vasoactive intestinal peptide [VIP]/NTM antibody) from December 1993 to June 1994. Her CD4 count increased to GT 400/muL during the passive immunotherapy and has remained stable for the past 6 years. The rational for the use of anti-VIP/NTM antibodies preparations in HIV, the possible mode of action of anti-VIP/NTM antibodies, the use of Ig preparations, and the role of exercise as a natural source of anti-VIP/NTM antibodies are discussed. This case report supports the potential therapeutic use of anti-VIP antibodies for treatment of HIV disease. | en |
dc.rights | restrictedAccess | en |
dc.source | Chest | en |
dc.subject | aerobic exercise | en |
dc.subject | AIDS | en |
dc.subject | anti-vasoactive intestinal peptide/NTM antibodies | en |
dc.subject | HIV | en |
dc.subject | Ig preparations | en |
dc.subject | passive immunization | en |
dc.subject | tuberculosis | en |
dc.title | The role of passive immunization in HIV-positive patients - A case report | en |
dc.type | article | en |
dcterms.abstract | Јевтовиц, Д; Стрингер, WW; Вељковић Вељко; Метлас Радмила; | |
dc.citation.volume | 120 | |
dc.citation.issue | 2 | |
dc.citation.spage | 662 | |
dc.citation.epage | 666 | |
dc.identifier.wos | 000170405500056 | |
dc.identifier.doi | 10.1378/chest.120.2.662 | |
dc.citation.rank | M21 | |
dc.identifier.pmid | 11502675 | |
dc.identifier.scopus | 2-s2.0-0034837728 |
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