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dc.creatorStanković, Srboljub J.
dc.creatorSpasojevic-Kalimanovska, V
dc.creatorAlavantić, Dragan
dc.date.accessioned2018-03-01T18:51:58Z
dc.date.available2018-03-01T18:51:58Z
dc.date.issued2000
dc.identifier.issn0354-3447 (print)
dc.identifier.urihttp://vinar.vin.bg.ac.rs/handle/123456789/2356
dc.description.abstractApolipoprotein E (apoE) genotypes were determined in a subset of 591 subjects by restriction isotyping/MADGE analysis. The characterization of different apoE isoforms (133 subjects) has also been carried out by isoelectric focussing/immunoblotting of plasma. In men, levels of both total and low-density lipoprotein cholesterol among the three apoE genotype groups (E2, E3, E4) differed significantly (p LT 0.05). The E2 allele was associated with the lower both total and low-density lipoprotein cholesterol, where the E4 allele had the opposite effects. In women, no significant effect of apoE polymorphism on serum lipid levels was observed. These data could be taken into consideration in the future evaluation of the risk of cardiovascular and/or neurodegenerative diseases in Serbian population.en
dc.rightsrestrictedAccessen
dc.sourceJugoslovenska Medicinska Biohemijaen
dc.subjectapo Een
dc.subjectrestriction isotypingen
dc.subjectlipidsen
dc.subjectgenetic epidemiologyen
dc.subjectSerbian populationen
dc.titleAssociation of apoE polymorphism with serum lipids in Serbian healthy populationen
dc.typearticleen
dcterms.abstractСтанковиц, С; Спасојевиц-Калимановска, В; Aлавантић Драган;
dc.citation.volume19
dc.citation.issue2
dc.citation.spage115
dc.citation.epage120
dc.identifier.wos000087763200006
dc.citation.rankM23


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