Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites
Samo za registrovane korisnike
2017
Autori
Malagurski, IvanaLevic, Steva

Pantic, Milena
Matijasevic, Danka
Mitrić, Miodrag

Pavlović, Vladimir B.

Dimitrijević-Branković, Suzana I.

Članak u časopisu
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
New bioactive and antimicrobial biomaterials were produced by alginate-mediated biomineralization with Zn-mineral phase. The synthesis procedure is simple, cost-effective and resulted in. two different Zn-mineralized alginate nanocomposites, Zn-carbonate/Zn-alginate and Zn-phosphate/Zn-alginate. The presence of Zn-mineral phase and its type, have significantly affected nanocomposite morphology, stability, total metallic loading and potential to release Zn(II) in physiological environment. Antimicrobial experiments showed that both types of Zn-mineralized nanocomposites exhibit strong antimicrobial effect against Escherichia coli, Staphylococcus aureus and Candida albicans. These results suggest that alginate biomineralization, where minerals are salts of essential metallic ions like Zn(II), represents agood strategy for designing multifunctional biomaterials for potential biomedical applications. (C) 2017 Elsevier Ltd. All rights reserved.
Ključne reči:
Zinc / Alginate / Nanocomposite / Biomineralization / Antimicrobial activityIzvor:
Carbohydrate Polymers, 2017, 165, 313-321Projekti:
- Sinteza, razvoj tehnologija dobijanja i primena nanostrukturnih multifunkcionalnih materijala definisanih svojstava (RS-45019)
- Usmerena sinteza, struktura i svojstva multifunkcionalnih materijala (RS-172057)
DOI: 10.1016/j.carbpol.2017.02.064
ISSN: 0144-8617 (print); 1879-1344 (electronic)
PubMed: 28363555