Genoprotective Capacity of Alternatively Cultivated Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Basidiocarps
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Аутори
Ćilerdžić, JasminaStajić, Mirjana
Živković, Lada
Vukojević, Jelena
Bajić, Vladan P.
Spremo-Potparević, Biljana
Чланак у часопису (Објављена верзија)
Метаподаци
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Ganoderma lucidum is traditionally used in Eastern medicine to preserve vitality, promote longevity, and treat disease. It possesses immunomodulatory, antitumor, antimicrobial, and antiaging activities, among others, but one of the most important is its antioxidant property, which is the basis for other effects, because free radicals trigger many diseases. The substrate commonly used for commercial cultivation of G. lucidum is not environmenwas to analyze the effect of substrate composition on the bioactivity of G. lucidum basidiocarps. G. lucidum was cultivated on 2 different substrates: (1) a mixture of wheat straw, grapevine branches, and wheat bran, and (2) wheat straw. Commercial fruiting bodies, cultivated on oak sawdust, were used as the control. 1,1- diphenyl- 2- picrylhydrazyl (DPPH) The comet test was performed to detect the degree of DNA damage in the cells that were exposed to G. lucidum extracts before and after the effect of oxidants. Higher antioxidative potential was ob...served for the extract of G. lucidum basidiocarps cultivated on wheat straw compared with that from the mixed substrate and especially with commercial ones. The alternatively cultivated basidiocarps also showed stronger antigenotoxic potential compared with commercial ones. The study showed that fruiting bodies produced on wheat straw, one of the most accessible and cheapest crop residues, are more potent antioxidant and antigenotoxic agents than commercially cultivated ones.
Кључне речи:
alternatively cultivated basidiocarp / antigenotoxic activity / antioxidant activity / commercial basidiocarp / Ganoderma lucidum / medicinal mushroomsИзвор:
International Journal of Medicinal Mushrooms, 2016, 18, 12, 1061-1069Финансирање / пројекти:
- Карактеризација и примена метаболита гљива и утврђивање потенцијала нових биофунгицида (RS-MESTD-Basic Research (BR or ON)-173032)
- Аберације ћелијског циклуса и утицај оксидативног стреса на неуродегенеративне процесе и малигну трансформацију ћелије (RS-MESTD-Basic Research (BR or ON)-173034)
DOI: 10.1615/IntJMedMushrooms.v18.i12.10
ISSN: 1521-9437; 1940-4344
PubMed: 28094744
WoS: 000395937300001
Scopus: 2-s2.0-85015348727
Колекције
Институција/група
VinčaTY - JOUR AU - Ćilerdžić, Jasmina AU - Stajić, Mirjana AU - Živković, Lada AU - Vukojević, Jelena AU - Bajić, Vladan P. AU - Spremo-Potparević, Biljana PY - 2016 UR - https://vinar.vin.bg.ac.rs/handle/123456789/1448 AB - Ganoderma lucidum is traditionally used in Eastern medicine to preserve vitality, promote longevity, and treat disease. It possesses immunomodulatory, antitumor, antimicrobial, and antiaging activities, among others, but one of the most important is its antioxidant property, which is the basis for other effects, because free radicals trigger many diseases. The substrate commonly used for commercial cultivation of G. lucidum is not environmenwas to analyze the effect of substrate composition on the bioactivity of G. lucidum basidiocarps. G. lucidum was cultivated on 2 different substrates: (1) a mixture of wheat straw, grapevine branches, and wheat bran, and (2) wheat straw. Commercial fruiting bodies, cultivated on oak sawdust, were used as the control. 1,1- diphenyl- 2- picrylhydrazyl (DPPH) The comet test was performed to detect the degree of DNA damage in the cells that were exposed to G. lucidum extracts before and after the effect of oxidants. Higher antioxidative potential was observed for the extract of G. lucidum basidiocarps cultivated on wheat straw compared with that from the mixed substrate and especially with commercial ones. The alternatively cultivated basidiocarps also showed stronger antigenotoxic potential compared with commercial ones. The study showed that fruiting bodies produced on wheat straw, one of the most accessible and cheapest crop residues, are more potent antioxidant and antigenotoxic agents than commercially cultivated ones. T2 - International Journal of Medicinal Mushrooms T1 - Genoprotective Capacity of Alternatively Cultivated Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Basidiocarps VL - 18 IS - 12 SP - 1061 EP - 1069 DO - 10.1615/IntJMedMushrooms.v18.i12.10 ER -
@article{ author = "Ćilerdžić, Jasmina and Stajić, Mirjana and Živković, Lada and Vukojević, Jelena and Bajić, Vladan P. and Spremo-Potparević, Biljana", year = "2016", abstract = "Ganoderma lucidum is traditionally used in Eastern medicine to preserve vitality, promote longevity, and treat disease. It possesses immunomodulatory, antitumor, antimicrobial, and antiaging activities, among others, but one of the most important is its antioxidant property, which is the basis for other effects, because free radicals trigger many diseases. The substrate commonly used for commercial cultivation of G. lucidum is not environmenwas to analyze the effect of substrate composition on the bioactivity of G. lucidum basidiocarps. G. lucidum was cultivated on 2 different substrates: (1) a mixture of wheat straw, grapevine branches, and wheat bran, and (2) wheat straw. Commercial fruiting bodies, cultivated on oak sawdust, were used as the control. 1,1- diphenyl- 2- picrylhydrazyl (DPPH) The comet test was performed to detect the degree of DNA damage in the cells that were exposed to G. lucidum extracts before and after the effect of oxidants. Higher antioxidative potential was observed for the extract of G. lucidum basidiocarps cultivated on wheat straw compared with that from the mixed substrate and especially with commercial ones. The alternatively cultivated basidiocarps also showed stronger antigenotoxic potential compared with commercial ones. The study showed that fruiting bodies produced on wheat straw, one of the most accessible and cheapest crop residues, are more potent antioxidant and antigenotoxic agents than commercially cultivated ones.", journal = "International Journal of Medicinal Mushrooms", title = "Genoprotective Capacity of Alternatively Cultivated Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Basidiocarps", volume = "18", number = "12", pages = "1061-1069", doi = "10.1615/IntJMedMushrooms.v18.i12.10" }
Ćilerdžić, J., Stajić, M., Živković, L., Vukojević, J., Bajić, V. P.,& Spremo-Potparević, B.. (2016). Genoprotective Capacity of Alternatively Cultivated Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Basidiocarps. in International Journal of Medicinal Mushrooms, 18(12), 1061-1069. https://doi.org/10.1615/IntJMedMushrooms.v18.i12.10
Ćilerdžić J, Stajić M, Živković L, Vukojević J, Bajić VP, Spremo-Potparević B. Genoprotective Capacity of Alternatively Cultivated Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Basidiocarps. in International Journal of Medicinal Mushrooms. 2016;18(12):1061-1069. doi:10.1615/IntJMedMushrooms.v18.i12.10 .
Ćilerdžić, Jasmina, Stajić, Mirjana, Živković, Lada, Vukojević, Jelena, Bajić, Vladan P., Spremo-Potparević, Biljana, "Genoprotective Capacity of Alternatively Cultivated Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Basidiocarps" in International Journal of Medicinal Mushrooms, 18, no. 12 (2016):1061-1069, https://doi.org/10.1615/IntJMedMushrooms.v18.i12.10 . .