Show simple item record

dc.creatorSpasojević, Dragica
dc.creatorZmejkoski, Danica
dc.creatorGlamočlija, Jasmina
dc.creatorNikolic, Milos
dc.creatorSoković, Marina
dc.creatorMilosevic, Verica
dc.creatorJaric, Ivana
dc.creatorStojanovic, Marijana
dc.creatorMarinkovic, Emilija
dc.creatorBarisani-Asenbauer, Talin
dc.creatorProdanovic, Radivoje
dc.creatorJovanovic, Milos
dc.creatorRadotić, Ksenija
dc.date.accessioned2018-03-01T17:16:42Z
dc.date.available2018-03-01T17:16:42Z
dc.date.issued2016
dc.identifier.issn0924-8579 (print)
dc.identifier.issn1872-7913 (electronic)
dc.identifier.urihttp://vinar.vin.bg.ac.rs/handle/123456789/1336
dc.description.abstractNowadays bacterial resistance to known antibiotics is a serious health problem. In order to achieve more efficient treatment, lately there is an effort to find new substances, such as certain biomaterials, that are non-toxic to humans with antibiotic potential. Lignins and lignin-derived compounds have been proposed to be good candidates for use in medicine and health maintenance. In this study, the antibacterial activity of the lignin model polymer dehydrogenate polymer (DHP) in alginate hydrogel (Alg) was studied. The obtained results show that DHP-Alg has strong antimicrobial activity against several bacterial strains and biofilms and does not have a toxic effect on human epithelial cells. These results strongly suggest its application as a wound healing agent or as an adjunct substance for wound treatments. (C) 2016 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.en
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/45012/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173017/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173032/RS//
dc.rightsrestrictedAccessen
dc.sourceInternational Journal of Antimicrobial Agentsen
dc.subjectLignin model polymeren
dc.subjectAlginateen
dc.subjectAntimicrobial activityen
dc.subjectBacterial biofilmen
dc.subjectWound treatmenten
dc.titleLignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatmenten
dc.typearticleen
dcterms.abstractСпасојевиц, Драгица; Стојановиц, Маријана; Соковиц, Марина; Барисани-Aсенбауер, Талин; Змејкоски, Даница; Милосевиц, Верица; Јовановиц, Милос; Маринковиц, Емилија; Јариц, Ивана; Радотиц, Ксенија; Николиц, Милос; Гламоцлија, Јасмина; Продановиц, Радивоје;
dc.citation.volume48
dc.citation.issue6
dc.citation.spage732
dc.citation.epage735
dc.identifier.wos000389520700024
dc.identifier.doi10.1016/j.ijantimicag.2016.08.014
dc.citation.rankM21
dc.identifier.pmid27742207
dc.identifier.scopus2-s2.0-85000995852


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record