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dc.creatorIvanovic, Vesna
dc.creatorDedović-Tanić, Nasta
dc.creatorMilovanović, Zorka M.
dc.creatorLukic, Silvana
dc.creatorNikolic, Srdjan
dc.creatorBaltic, Vladimir
dc.creatorStojiljkovic, Bratislav
dc.creatorDemajo, Miroslav
dc.creatorMandušić, Vesna
dc.creatorDimitrijević, Bogomir B.
dc.date.accessioned2018-03-01T17:15:55Z
dc.date.available2018-03-01T17:15:55Z
dc.date.issued2016
dc.identifier.issn1741-0541 (print)
dc.identifier.issn1744-828X (electronic)
dc.identifier.urihttp://vinar.vin.bg.ac.rs/handle/123456789/1327
dc.description.abstractWe present herein a case report style article on a rare advanced triple-negative breast cancer (TNBC) patient with 6-month disease-free interval, and 10-month overall survival. Our results demonstrate that the poor clinical outcome of this patient was associated with pronounced, more than fivefold higher, overexpression of both cFOS and TGF-beta 1 proteins in its metastatic nodal tissue extracts, when compared with the values of the two non-TNBC controls (with zero disease-free interval and overall survival). This original observation suggests, for the first time, that both the cFOS and TGF-beta 1 may be considered as a pair of biomarkers for an early assessment of poor prognosis for TNBC patients. The possible clinical implication of this observation is discussed.en
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173049/RS//
dc.rightsrestrictedAccessen
dc.sourcePersonalized Medicineen
dc.subjectcFOSen
dc.subjectmetastatic axillary lymph nodesen
dc.subjectTGF-beta 1en
dc.subjecttriple-negative breast canceren
dc.titleCase with triple-negative breast cancer shows overexpression of both cFOS and TGF-beta 1 in node-positive tissueen
dc.typearticleen
dcterms.abstractНиколиц, Срдјан; Мандушић Весна; Миловановиц, Зорка; Димитријевић Богомир Б.; Лукиц, Силвана; Ивановиц, Весна; Стојиљковиц, Братислав; Балтиц, Владимир; Дедовиц-Таниц, Наста; Демајо, Мирослав;
dc.citation.volume13
dc.citation.issue6
dc.citation.spage523
dc.citation.epage530
dc.identifier.wos000389179500001
dc.identifier.doi10.2217/pme-2016-0032
dc.citation.rankM23
dc.identifier.scopus2-s2.0-84994558857


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