Phenolic Composition and Cytotoxic Activity of Red Wine
Само за регистроване кориснике
2022
Аутори
Đorđević, NedaTodorović Vukotić, Nevena
Korićanac, Lela
Žakula, Jelena
Pejić, Snežana
Pajović, Snežana B.
Tešević, V.
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Positive effects of moderate wine consumption in individuals with cardiovascular disease, hypertension, diabetes, and cancers have been shown in numerous epidemiological and clinical studies. This research examined the phenolic content of commercial and two clonal Merlot wines as well as their biological potential. The obtained results indicated that all analyzed samples were a good source of phenolic compounds. Cytotoxicity assay on melanoma (A375) and cervical (HeLa) cancer cell lines have shown that all analyzed wines inhibited the growth of human cancer cells in vitro with differing susceptibility among tested cell lines. Clonal wines in the volume ratio of 10 and 20% showed to be more efficient anti-proliferative agents than commercial wine regarding the A375 cells. This could be connected with higher total phenolic content in clonal wines. The effect of all analyzed samples on the A375 cells was greater compared to HeLa cell line.
Извор:
16th International Conference on Fundamental and Applied Aspects of Physical Chemistry - Physical Chemistry 2022 : Book of Abstracts, 2022, 153-153Издавач:
- Belgrade : Society of Physical Chemists of Serbia
Напомена:
- XVI International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 26-30, Belgrade
Колекције
Институција/група
VinčaTY - CONF AU - Đorđević, Neda AU - Todorović Vukotić, Nevena AU - Korićanac, Lela AU - Žakula, Jelena AU - Pejić, Snežana AU - Pajović, Snežana B. AU - Tešević, V. PY - 2022 UR - https://vinar.vin.bg.ac.rs/handle/123456789/12586 AB - Positive effects of moderate wine consumption in individuals with cardiovascular disease, hypertension, diabetes, and cancers have been shown in numerous epidemiological and clinical studies. This research examined the phenolic content of commercial and two clonal Merlot wines as well as their biological potential. The obtained results indicated that all analyzed samples were a good source of phenolic compounds. Cytotoxicity assay on melanoma (A375) and cervical (HeLa) cancer cell lines have shown that all analyzed wines inhibited the growth of human cancer cells in vitro with differing susceptibility among tested cell lines. Clonal wines in the volume ratio of 10 and 20% showed to be more efficient anti-proliferative agents than commercial wine regarding the A375 cells. This could be connected with higher total phenolic content in clonal wines. The effect of all analyzed samples on the A375 cells was greater compared to HeLa cell line. PB - Belgrade : Society of Physical Chemists of Serbia C3 - 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry - Physical Chemistry 2022 : Book of Abstracts T1 - Phenolic Composition and Cytotoxic Activity of Red Wine SP - 153 EP - 153 UR - https://hdl.handle.net/21.15107/rcub_vinar_12586 ER -
@conference{ author = "Đorđević, Neda and Todorović Vukotić, Nevena and Korićanac, Lela and Žakula, Jelena and Pejić, Snežana and Pajović, Snežana B. and Tešević, V.", year = "2022", abstract = "Positive effects of moderate wine consumption in individuals with cardiovascular disease, hypertension, diabetes, and cancers have been shown in numerous epidemiological and clinical studies. This research examined the phenolic content of commercial and two clonal Merlot wines as well as their biological potential. The obtained results indicated that all analyzed samples were a good source of phenolic compounds. Cytotoxicity assay on melanoma (A375) and cervical (HeLa) cancer cell lines have shown that all analyzed wines inhibited the growth of human cancer cells in vitro with differing susceptibility among tested cell lines. Clonal wines in the volume ratio of 10 and 20% showed to be more efficient anti-proliferative agents than commercial wine regarding the A375 cells. This could be connected with higher total phenolic content in clonal wines. The effect of all analyzed samples on the A375 cells was greater compared to HeLa cell line.", publisher = "Belgrade : Society of Physical Chemists of Serbia", journal = "16th International Conference on Fundamental and Applied Aspects of Physical Chemistry - Physical Chemistry 2022 : Book of Abstracts", title = "Phenolic Composition and Cytotoxic Activity of Red Wine", pages = "153-153", url = "https://hdl.handle.net/21.15107/rcub_vinar_12586" }
Đorđević, N., Todorović Vukotić, N., Korićanac, L., Žakula, J., Pejić, S., Pajović, S. B.,& Tešević, V.. (2022). Phenolic Composition and Cytotoxic Activity of Red Wine. in 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry - Physical Chemistry 2022 : Book of Abstracts Belgrade : Society of Physical Chemists of Serbia., 153-153. https://hdl.handle.net/21.15107/rcub_vinar_12586
Đorđević N, Todorović Vukotić N, Korićanac L, Žakula J, Pejić S, Pajović SB, Tešević V. Phenolic Composition and Cytotoxic Activity of Red Wine. in 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry - Physical Chemistry 2022 : Book of Abstracts. 2022;:153-153. https://hdl.handle.net/21.15107/rcub_vinar_12586 .
Đorđević, Neda, Todorović Vukotić, Nevena, Korićanac, Lela, Žakula, Jelena, Pejić, Snežana, Pajović, Snežana B., Tešević, V., "Phenolic Composition and Cytotoxic Activity of Red Wine" in 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry - Physical Chemistry 2022 : Book of Abstracts (2022):153-153, https://hdl.handle.net/21.15107/rcub_vinar_12586 .