Improvement of Au-poly(N-isopropylacrylamide) hydrogel nanocomposites: Singlelayer vs. bi-layered systems
Аутори
Nikolić, NikolinaSpasojević, Jelena
Stamenović, Una
Vodnik, Vesna
Vukoje, Ivana
Kačarević-Popović, Zorica
Radosavljević, Aleksandra
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
In recent years, the need for innovative materials has produced remarkable progress in the field of smart materials, with a particular focus on nanocomposite systems containing crosslinked polymer matrices (hydrogels) and metal nanoparticles. Hydrogels have become a crucial class of biomaterials due to their stable 3D porous structures, high fluid absorption capacity, similarity to biological tissues, and biocompatibility. Of particular interest are hydrogels with the ability to respond to various external stimuli (temperature, pH, light etc.), resulting in alterations of their physical and chemical characteristics. Our research focuses on the nanocomposites based on thermosensitive poly(N-isopropylacrylamide) (PNiPAAm) hydrogels and gold nanoparticles (AuNPs), with a unique emphasis on exploring the specific properties of single-layer and bi-layered systems. The insights gained from this comparative study open new possibilities for applications in drug delivery, sensors, and soft robo...tics. Single-layer systems consisting of active PNiPAAm hydrogel and AuNPs, were created through a combination of radiolytic and chemical procedures. Bi-layered systems feature an active Au-PNiPAAm layer, with the addition of a passive poly(vinyl alcohol) (PVA) hydrogel layer, crosslinked by the combination of freeze-thaw and radiolytic techniques. In both cases, the incorporation of spherical AuNPs within an active layer was confirmed by the presence of a characteristic surface plasmon resonance (SPR), while scanning electron microscopy (SEM) indicated the system's highly porous structure. The physicochemical properties of both single- and bi-layered systems involved the examination of their swelling and deswelling properties, as well as the volume phase transition temperature (VPTT). The incorporation of AuNPs in the PNiPAAm layer led to an increase in both swelling capacity and VPTT. Compression measurements showed that the presence of a passive layer and AuNPs significantly improved mechanical properties of nanocomposites.
Извор:
21st Young Researchers' Conference Materials Sciences and Engineering : program and the book of abstracts, 2023, 54-54Издавач:
- Belgrade : Institute of Technical Sciences of SASA
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200017 (Универзитет у Београду, Институт за нуклеарне науке Винча, Београд-Винча) (RS-MESTD-inst-2020-200017)
- International Atomic Energy Agency [CRP F22070, Contract No. 23184]
Напомена:
- Twenty-First Young Researchers’ Conference - Materials Science and Engineering: Program and the Book of Abstracts; November 29 – December 1, 2023, Belgrade, Serbia
Колекције
Институција/група
VinčaTY - CONF AU - Nikolić, Nikolina AU - Spasojević, Jelena AU - Stamenović, Una AU - Vodnik, Vesna AU - Vukoje, Ivana AU - Kačarević-Popović, Zorica AU - Radosavljević, Aleksandra PY - 2023 UR - https://vinar.vin.bg.ac.rs/handle/123456789/12325 AB - In recent years, the need for innovative materials has produced remarkable progress in the field of smart materials, with a particular focus on nanocomposite systems containing crosslinked polymer matrices (hydrogels) and metal nanoparticles. Hydrogels have become a crucial class of biomaterials due to their stable 3D porous structures, high fluid absorption capacity, similarity to biological tissues, and biocompatibility. Of particular interest are hydrogels with the ability to respond to various external stimuli (temperature, pH, light etc.), resulting in alterations of their physical and chemical characteristics. Our research focuses on the nanocomposites based on thermosensitive poly(N-isopropylacrylamide) (PNiPAAm) hydrogels and gold nanoparticles (AuNPs), with a unique emphasis on exploring the specific properties of single-layer and bi-layered systems. The insights gained from this comparative study open new possibilities for applications in drug delivery, sensors, and soft robotics. Single-layer systems consisting of active PNiPAAm hydrogel and AuNPs, were created through a combination of radiolytic and chemical procedures. Bi-layered systems feature an active Au-PNiPAAm layer, with the addition of a passive poly(vinyl alcohol) (PVA) hydrogel layer, crosslinked by the combination of freeze-thaw and radiolytic techniques. In both cases, the incorporation of spherical AuNPs within an active layer was confirmed by the presence of a characteristic surface plasmon resonance (SPR), while scanning electron microscopy (SEM) indicated the system's highly porous structure. The physicochemical properties of both single- and bi-layered systems involved the examination of their swelling and deswelling properties, as well as the volume phase transition temperature (VPTT). The incorporation of AuNPs in the PNiPAAm layer led to an increase in both swelling capacity and VPTT. Compression measurements showed that the presence of a passive layer and AuNPs significantly improved mechanical properties of nanocomposites. PB - Belgrade : Institute of Technical Sciences of SASA C3 - 21st Young Researchers' Conference Materials Sciences and Engineering : program and the book of abstracts T1 - Improvement of Au-poly(N-isopropylacrylamide) hydrogel nanocomposites: Singlelayer vs. bi-layered systems SP - 54 EP - 54 UR - https://hdl.handle.net/21.15107/rcub_vinar_12325 ER -
@conference{ author = "Nikolić, Nikolina and Spasojević, Jelena and Stamenović, Una and Vodnik, Vesna and Vukoje, Ivana and Kačarević-Popović, Zorica and Radosavljević, Aleksandra", year = "2023", abstract = "In recent years, the need for innovative materials has produced remarkable progress in the field of smart materials, with a particular focus on nanocomposite systems containing crosslinked polymer matrices (hydrogels) and metal nanoparticles. Hydrogels have become a crucial class of biomaterials due to their stable 3D porous structures, high fluid absorption capacity, similarity to biological tissues, and biocompatibility. Of particular interest are hydrogels with the ability to respond to various external stimuli (temperature, pH, light etc.), resulting in alterations of their physical and chemical characteristics. Our research focuses on the nanocomposites based on thermosensitive poly(N-isopropylacrylamide) (PNiPAAm) hydrogels and gold nanoparticles (AuNPs), with a unique emphasis on exploring the specific properties of single-layer and bi-layered systems. The insights gained from this comparative study open new possibilities for applications in drug delivery, sensors, and soft robotics. Single-layer systems consisting of active PNiPAAm hydrogel and AuNPs, were created through a combination of radiolytic and chemical procedures. Bi-layered systems feature an active Au-PNiPAAm layer, with the addition of a passive poly(vinyl alcohol) (PVA) hydrogel layer, crosslinked by the combination of freeze-thaw and radiolytic techniques. In both cases, the incorporation of spherical AuNPs within an active layer was confirmed by the presence of a characteristic surface plasmon resonance (SPR), while scanning electron microscopy (SEM) indicated the system's highly porous structure. The physicochemical properties of both single- and bi-layered systems involved the examination of their swelling and deswelling properties, as well as the volume phase transition temperature (VPTT). The incorporation of AuNPs in the PNiPAAm layer led to an increase in both swelling capacity and VPTT. Compression measurements showed that the presence of a passive layer and AuNPs significantly improved mechanical properties of nanocomposites.", publisher = "Belgrade : Institute of Technical Sciences of SASA", journal = "21st Young Researchers' Conference Materials Sciences and Engineering : program and the book of abstracts", title = "Improvement of Au-poly(N-isopropylacrylamide) hydrogel nanocomposites: Singlelayer vs. bi-layered systems", pages = "54-54", url = "https://hdl.handle.net/21.15107/rcub_vinar_12325" }
Nikolić, N., Spasojević, J., Stamenović, U., Vodnik, V., Vukoje, I., Kačarević-Popović, Z.,& Radosavljević, A.. (2023). Improvement of Au-poly(N-isopropylacrylamide) hydrogel nanocomposites: Singlelayer vs. bi-layered systems. in 21st Young Researchers' Conference Materials Sciences and Engineering : program and the book of abstracts Belgrade : Institute of Technical Sciences of SASA., 54-54. https://hdl.handle.net/21.15107/rcub_vinar_12325
Nikolić N, Spasojević J, Stamenović U, Vodnik V, Vukoje I, Kačarević-Popović Z, Radosavljević A. Improvement of Au-poly(N-isopropylacrylamide) hydrogel nanocomposites: Singlelayer vs. bi-layered systems. in 21st Young Researchers' Conference Materials Sciences and Engineering : program and the book of abstracts. 2023;:54-54. https://hdl.handle.net/21.15107/rcub_vinar_12325 .
Nikolić, Nikolina, Spasojević, Jelena, Stamenović, Una, Vodnik, Vesna, Vukoje, Ivana, Kačarević-Popović, Zorica, Radosavljević, Aleksandra, "Improvement of Au-poly(N-isopropylacrylamide) hydrogel nanocomposites: Singlelayer vs. bi-layered systems" in 21st Young Researchers' Conference Materials Sciences and Engineering : program and the book of abstracts (2023):54-54, https://hdl.handle.net/21.15107/rcub_vinar_12325 .