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Vanillic aldehydes for the one-pot synthesis of novel 2-oxo-1,2,3,4-tetrahydropyrimidines
dc.creator | Muškinja, Jovana | |
dc.creator | Janković, Nenad | |
dc.creator | Ratković, Zoran R. | |
dc.creator | Bogdanović, Goran A. | |
dc.creator | Bugarčič, Zorica M. | |
dc.date.accessioned | 2018-03-01T17:01:35Z | |
dc.date.available | 2018-03-01T17:01:35Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 1381-1991 | |
dc.identifier.issn | 1573-501X | |
dc.identifier.uri | https://vinar.vin.bg.ac.rs/handle/123456789/1163 | |
dc.description.abstract | A small library of novel 2-oxo-1,2,3,4-tetrahydropyrimidines was synthesized via a one-pot multicomponent Biginelli reaction. Copper complex which was used for the first time as a homogeneous and heterogeneous catalyst, makes this a facile and efficient reaction at room temperature. All the obtained products fall out of the solution in pure form and are easily isolated via filtration in good-to-excellent yields. The molecular structure of one of the products, ethyl 6-methyl-2-oxo-4-(4-isopropoxy-3-methoxyphenyl) - 1,2,3,4 - tetrahydropyrimidine-5- carboxylate, has been determined by X-ray crystallography. All non-hydrogen atoms in the heterocyclic, six-membered ring are determined to be approximately coplanar. | en |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172011/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172034/RS// | |
dc.rights | restrictedAccess | en |
dc.source | Molecular Diversity | en |
dc.subject | Homogeneous catalysis | en |
dc.subject | Heterogeneous catalysis | en |
dc.subject | Multicomponent reactions (MCRs) | en |
dc.subject | Heterocycles | en |
dc.title | Vanillic aldehydes for the one-pot synthesis of novel 2-oxo-1,2,3,4-tetrahydropyrimidines | en |
dc.type | article | en |
dcterms.abstract | Јанковиц, Ненад; Богдановић Горан; Бугарциц, Зорица; Ратковиц, Зоран; Мускиња, Јована; | |
dc.citation.volume | 20 | |
dc.citation.issue | 3 | |
dc.citation.spage | 591 | |
dc.citation.epage | 604 | |
dc.identifier.wos | 000379259200002 | |
dc.identifier.doi | 10.1007/s11030-016-9658-y | |
dc.citation.rank | M22 | |
dc.identifier.pmid | 26829937 | |
dc.type.version | publishedVersion | |
dc.identifier.scopus | 2-s2.0-84977450850 |