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dc.creatorMuskinja, Jovana
dc.creatorJankovic, Nenad
dc.creatorRatkovic, Zoran
dc.creatorBogdanović, Goran A.
dc.creatorBugarcic, Zorica
dc.date.accessioned2018-03-01T17:01:35Z
dc.date.available2018-03-01T17:01:35Z
dc.date.issued2016
dc.identifier.issn1381-1991 (print)
dc.identifier.issn1573-501X (electronic)
dc.identifier.urihttp://vinar.vin.bg.ac.rs/handle/123456789/1163
dc.description.abstractA small library of novel 2-oxo-1,2,3,4-tetrahydropyrimidines was synthesized via a one-pot multicomponent Biginelli reaction. Copper complex which was used for the first time as a homogeneous and heterogeneous catalyst, makes this a facile and efficient reaction at room temperature. All the obtained products fall out of the solution in pure form and are easily isolated via filtration in good-to-excellent yields. The molecular structure of one of the products, ethyl 6-methyl-2-oxo-4-(4-isopropoxy-3-methoxyphenyl) - 1,2,3,4 - tetrahydropyrimidine-5- carboxylate, has been determined by X-ray crystallography. All non-hydrogen atoms in the heterocyclic, six-membered ring are determined to be approximately coplanar.en
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172011/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172034/RS//
dc.rightsrestrictedAccessen
dc.sourceMolecular Diversityen
dc.subjectHomogeneous catalysisen
dc.subjectHeterogeneous catalysisen
dc.subjectMulticomponent reactions (MCRs)en
dc.subjectHeterocyclesen
dc.titleVanillic aldehydes for the one-pot synthesis of novel 2-oxo-1,2,3,4-tetrahydropyrimidinesen
dc.typearticleen
dcterms.abstractЈанковиц, Ненад; Богдановић Горан; Бугарциц, Зорица; Ратковиц, Зоран; Мускиња, Јована;
dc.citation.volume20
dc.citation.issue3
dc.citation.spage591
dc.citation.epage604
dc.identifier.wos000379259200002
dc.identifier.doi10.1007/s11030-016-9658-y
dc.citation.rankM22
dc.identifier.pmid26829937
dc.identifier.scopus2-s2.0-84977450850


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