Cell Response on Laser-Patterned Ti/Zr/Ti and Ti/Cu/Ti Multilayer Systems
Аутори
Petrović, SuzanaBožinović, Nevena
Rajić, Vladimir
Stanisavljević Ninković, Danijela
Kisić, Danilo
Stevanović, Milena J.
Stratakis, Emmanuel
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Arranged patterns obtained via ultrafast laser processing on the surface of Ti/Cu/Ti/Si and Ti/Zr/Ti/Si thin-film systems are reported. Two differently designed multilayer thin films Ti/Cu/Ti/Si and Ti/Zr/Ti/Si were deposited on silicon using the ion sputtering method. The bioactive surfaces of these systems involve the formation of laser-induced periodic surface structures (LIPSS) in each of the laser-written lines of mesh patterns on 5 × 5 mm areas. The formation of nano- and micro-patterns with an ultra-thin oxide film on the surfaces was used to observe the effects of morphology and proliferation of the MRC-5 cell culture line. To determine whether Ti-based thin films have a toxic effect on living cells, an MTT assay was performed. The relative cytotoxic effect, as a percentage of surviving cells, showed that there was no difference in cell number between the Ti-based thin films and the control cells. There was also no difference in the viability of the MRC-5 cells, except for the ...Ti/Cu/Ti/Si system, where there was a slight 10% decrease in cell viability. © 2023 by the authors.
Кључне речи:
cell response / laser modification / laser-induced periodical surface structure LIPSS / multilayer thin filmsИзвор:
Coatings, 2023, 13, 6, 1107-Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200017 (Универзитет у Београду, Институт за нуклеарне науке Винча, Београд-Винча) (RS-MESTD-inst-2020-200017)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200042 (Универзитет у Београду, Институт за молекуларну генетику и генетичко инжењерство) (RS-MESTD-inst-2020-200042)
- COST Action [Project no. CA21159 (PhoBios)]
Колекције
Институција/група
VinčaTY - JOUR AU - Petrović, Suzana AU - Božinović, Nevena AU - Rajić, Vladimir AU - Stanisavljević Ninković, Danijela AU - Kisić, Danilo AU - Stevanović, Milena J. AU - Stratakis, Emmanuel PY - 2023 UR - https://vinar.vin.bg.ac.rs/handle/123456789/11368 AB - Arranged patterns obtained via ultrafast laser processing on the surface of Ti/Cu/Ti/Si and Ti/Zr/Ti/Si thin-film systems are reported. Two differently designed multilayer thin films Ti/Cu/Ti/Si and Ti/Zr/Ti/Si were deposited on silicon using the ion sputtering method. The bioactive surfaces of these systems involve the formation of laser-induced periodic surface structures (LIPSS) in each of the laser-written lines of mesh patterns on 5 × 5 mm areas. The formation of nano- and micro-patterns with an ultra-thin oxide film on the surfaces was used to observe the effects of morphology and proliferation of the MRC-5 cell culture line. To determine whether Ti-based thin films have a toxic effect on living cells, an MTT assay was performed. The relative cytotoxic effect, as a percentage of surviving cells, showed that there was no difference in cell number between the Ti-based thin films and the control cells. There was also no difference in the viability of the MRC-5 cells, except for the Ti/Cu/Ti/Si system, where there was a slight 10% decrease in cell viability. © 2023 by the authors. T2 - Coatings T1 - Cell Response on Laser-Patterned Ti/Zr/Ti and Ti/Cu/Ti Multilayer Systems VL - 13 IS - 6 SP - 1107 DO - 10.3390/coatings13061107 ER -
@article{ author = "Petrović, Suzana and Božinović, Nevena and Rajić, Vladimir and Stanisavljević Ninković, Danijela and Kisić, Danilo and Stevanović, Milena J. and Stratakis, Emmanuel", year = "2023", abstract = "Arranged patterns obtained via ultrafast laser processing on the surface of Ti/Cu/Ti/Si and Ti/Zr/Ti/Si thin-film systems are reported. Two differently designed multilayer thin films Ti/Cu/Ti/Si and Ti/Zr/Ti/Si were deposited on silicon using the ion sputtering method. The bioactive surfaces of these systems involve the formation of laser-induced periodic surface structures (LIPSS) in each of the laser-written lines of mesh patterns on 5 × 5 mm areas. The formation of nano- and micro-patterns with an ultra-thin oxide film on the surfaces was used to observe the effects of morphology and proliferation of the MRC-5 cell culture line. To determine whether Ti-based thin films have a toxic effect on living cells, an MTT assay was performed. The relative cytotoxic effect, as a percentage of surviving cells, showed that there was no difference in cell number between the Ti-based thin films and the control cells. There was also no difference in the viability of the MRC-5 cells, except for the Ti/Cu/Ti/Si system, where there was a slight 10% decrease in cell viability. © 2023 by the authors.", journal = "Coatings", title = "Cell Response on Laser-Patterned Ti/Zr/Ti and Ti/Cu/Ti Multilayer Systems", volume = "13", number = "6", pages = "1107", doi = "10.3390/coatings13061107" }
Petrović, S., Božinović, N., Rajić, V., Stanisavljević Ninković, D., Kisić, D., Stevanović, M. J.,& Stratakis, E.. (2023). Cell Response on Laser-Patterned Ti/Zr/Ti and Ti/Cu/Ti Multilayer Systems. in Coatings, 13(6), 1107. https://doi.org/10.3390/coatings13061107
Petrović S, Božinović N, Rajić V, Stanisavljević Ninković D, Kisić D, Stevanović MJ, Stratakis E. Cell Response on Laser-Patterned Ti/Zr/Ti and Ti/Cu/Ti Multilayer Systems. in Coatings. 2023;13(6):1107. doi:10.3390/coatings13061107 .
Petrović, Suzana, Božinović, Nevena, Rajić, Vladimir, Stanisavljević Ninković, Danijela, Kisić, Danilo, Stevanović, Milena J., Stratakis, Emmanuel, "Cell Response on Laser-Patterned Ti/Zr/Ti and Ti/Cu/Ti Multilayer Systems" in Coatings, 13, no. 6 (2023):1107, https://doi.org/10.3390/coatings13061107 . .