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Dehydrozingerone based 1-acetyl-5-aryl-4,5-dihydro-1H-pyrazoles: Synthesis, characterization and anticancer activity
| dc.creator | Ratković, Zoran R. | |
| dc.creator | Muškinja, Jovana | |
| dc.creator | Burmudžija, Adrijana | |
| dc.creator | Ranković, Branislav | |
| dc.creator | Kosanić, Marijana | |
| dc.creator | Bogdanović, Goran A. | |
| dc.creator | Marković-Simović, Bojana | |
| dc.creator | Nikolić, Aleksandar | |
| dc.creator | Arsenijević, Nebojša N. | |
| dc.creator | Đorđević, Snežana | |
| dc.creator | Vukićević, Rastko D. | |
| dc.date.accessioned | 2018-03-01T16:58:29Z | |
| dc.date.available | 2018-03-01T16:58:29Z | |
| dc.date.issued | 2016 | |
| dc.identifier.issn | 0022-2860 | |
| dc.identifier.issn | 1872-8014 | |
| dc.identifier.uri | https://vinar.vin.bg.ac.rs/handle/123456789/1127 | |
| dc.description.abstract | A small series of 1-acetyl-5-aryl-4,5-dihydro-1H-pyrazoles (aryl = 4-hydroxy-3-methoxyphenyl and 4-alkoxy-3-methoxyphenyl) was prepared, starting from 4-(4-hydroxy-3-methoxyphenyl)-3-buten-2-one, dehydrozingerone, and its alkyl derivatives. Their in vitro cytotoxic activity against some cancer cell lines was tested, showing significant anticancer activity. All the new compounds were well characterized by IR, H-1, C-13 NMR and ESI-MS spectroscopy and physical data, whereas structures of two of them were determined by single crystal X-ray analysis. (C) 2016 Elsevier B.V. All rights reserved. | en |
| dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172034/RS// | |
| dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172014/RS// | |
| dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175103/RS// | |
| dc.rights | restrictedAccess | en |
| dc.source | Journal of Molecular Structure | en |
| dc.subject | Dehydrozingerone | en |
| dc.subject | Anticancer | en |
| dc.subject | Cytotoxicity | en |
| dc.subject | Crystal structure | en |
| dc.title | Dehydrozingerone based 1-acetyl-5-aryl-4,5-dihydro-1H-pyrazoles: Synthesis, characterization and anticancer activity | en |
| dc.type | article | en |
| dc.rights.license | ARR | |
| dcterms.abstract | Николиц, Aлександар; Богдановић Горан; Косаниц, Маријана; Aрсенијевиц, Небојса; Ранковиц, Бранислав; Мускиња, Јована; Вукицевиц, Растко Д.; Дордевиц, Снезана; Бурмудзија, Aдријана; Марковиц, Бојана Симовиц; Ратковиц, Зоран; | |
| dc.citation.volume | 1109 | |
| dc.citation.spage | 82 | |
| dc.citation.epage | 88 | |
| dc.identifier.wos | 000378100700010 | |
| dc.identifier.doi | 10.1016/j.molstruc.2015.12.079 | |
| dc.citation.rank | M23 | |
| dc.type.version | publishedVersion | |
| dc.identifier.scopus | 2-s2.0-84953455358 |
