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dc.creatorRatkovic, Zoran
dc.creatorMuskinja, Jovana
dc.creatorBurmudzija, Adrijana
dc.creatorRankovic, Branislav
dc.creatorKosanic, Marijana
dc.creatorBogdanović, Goran A.
dc.creatorMarković-Simović, Bojana
dc.creatorNikolic, Aleksandar
dc.creatorArsenijević, Nebojša N.
dc.creatorDordevic, Snezana
dc.creatorVukicevic, Rastko D.
dc.date.accessioned2018-03-01T16:58:29Z
dc.date.available2018-03-01T16:58:29Z
dc.date.issued2016
dc.identifier.issn0022-2860 (print)
dc.identifier.issn1872-8014 (electronic)
dc.identifier.urihttp://vinar.vin.bg.ac.rs/handle/123456789/1127
dc.description.abstractA small series of 1-acetyl-5-aryl-4,5-dihydro-1H-pyrazoles (aryl = 4-hydroxy-3-methoxyphenyl and 4-alkoxy-3-methoxyphenyl) was prepared, starting from 4-(4-hydroxy-3-methoxyphenyl)-3-buten-2-one, dehydrozingerone, and its alkyl derivatives. Their in vitro cytotoxic activity against some cancer cell lines was tested, showing significant anticancer activity. All the new compounds were well characterized by IR, H-1, C-13 NMR and ESI-MS spectroscopy and physical data, whereas structures of two of them were determined by single crystal X-ray analysis. (C) 2016 Elsevier B.V. All rights reserved.en
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172034/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172014/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175103/RS//
dc.rightsrestrictedAccessen
dc.sourceJournal of Molecular Structureen
dc.subjectDehydrozingeroneen
dc.subjectAnticanceren
dc.subjectCytotoxicityen
dc.subjectCrystal structureen
dc.titleDehydrozingerone based 1-acetyl-5-aryl-4,5-dihydro-1H-pyrazoles: Synthesis, characterization and anticancer activityen
dc.typearticleen
dcterms.abstractНиколиц, Aлександар; Богдановић Горан; Косаниц, Маријана; Aрсенијевиц, Небојса; Ранковиц, Бранислав; Мускиња, Јована; Вукицевиц, Растко Д.; Дордевиц, Снезана; Бурмудзија, Aдријана; Марковиц, Бојана Симовиц; Ратковиц, Зоран;
dc.citation.volume1109
dc.citation.spage82
dc.citation.epage88
dc.identifier.wos000378100700010
dc.identifier.doi10.1016/j.molstruc.2015.12.079
dc.citation.rankM23
dc.identifier.scopus2-s2.0-84953455358


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