Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid
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Due to its similarity with biological apatite found in vertebrate hard tissues, calcium hydroxyapatite is one of the most investigated materials in bone tissue engineering. As the biological apatite is not stoichiometric, ion substituted hydroxyapatites attract much atention since they more closely mimic the composition of natural bone. Although there are many investigations of the influence of foreign ions on the structure and physico-chemical properties of ion-substituted hydroxyapatites, there is scarse information on their behaviour in different media. In the present study, magnesium (Mg), that plays a key role in bone metabolism and silicon (Si), that is necessary for normal skeletal development, were used as ion substitutes. The behaviour of Mg and Si substituted hydroxyapatite in simulated body fluid was investigated by XRD, FTIR and SEM. Obtained results confirmed great potential of these substituted hydroxyapatites for biomedical applications.
Кључне речи:
ubstituted hydroxyapatite / magnesium / silicon / SBFИзвор:
Stomatološki glasnik Srbije / Serbian Dental Journal, 2022, 69, 2, 82-88Финансирање / пројекти:
- Ministry of Education, Science and Technological Development of the Republic of Serbia (Theme 0402208)
Колекције
Институција/група
VinčaTY - JOUR AU - Petrović, Božana AU - Krstić, Maja AU - Mudrinić, Tihana AU - Čebela, Maria AU - Dutour-Sikirić, Maja PY - 2022 UR - https://vinar.vin.bg.ac.rs/handle/123456789/11133 AB - Due to its similarity with biological apatite found in vertebrate hard tissues, calcium hydroxyapatite is one of the most investigated materials in bone tissue engineering. As the biological apatite is not stoichiometric, ion substituted hydroxyapatites attract much atention since they more closely mimic the composition of natural bone. Although there are many investigations of the influence of foreign ions on the structure and physico-chemical properties of ion-substituted hydroxyapatites, there is scarse information on their behaviour in different media. In the present study, magnesium (Mg), that plays a key role in bone metabolism and silicon (Si), that is necessary for normal skeletal development, were used as ion substitutes. The behaviour of Mg and Si substituted hydroxyapatite in simulated body fluid was investigated by XRD, FTIR and SEM. Obtained results confirmed great potential of these substituted hydroxyapatites for biomedical applications. T2 - Stomatološki glasnik Srbije / Serbian Dental Journal T1 - Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid VL - 69 IS - 2 SP - 82 EP - 88 DO - 10.2298/SGS2202082P ER -
@article{ author = "Petrović, Božana and Krstić, Maja and Mudrinić, Tihana and Čebela, Maria and Dutour-Sikirić, Maja", year = "2022", abstract = "Due to its similarity with biological apatite found in vertebrate hard tissues, calcium hydroxyapatite is one of the most investigated materials in bone tissue engineering. As the biological apatite is not stoichiometric, ion substituted hydroxyapatites attract much atention since they more closely mimic the composition of natural bone. Although there are many investigations of the influence of foreign ions on the structure and physico-chemical properties of ion-substituted hydroxyapatites, there is scarse information on their behaviour in different media. In the present study, magnesium (Mg), that plays a key role in bone metabolism and silicon (Si), that is necessary for normal skeletal development, were used as ion substitutes. The behaviour of Mg and Si substituted hydroxyapatite in simulated body fluid was investigated by XRD, FTIR and SEM. Obtained results confirmed great potential of these substituted hydroxyapatites for biomedical applications.", journal = "Stomatološki glasnik Srbije / Serbian Dental Journal", title = "Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid", volume = "69", number = "2", pages = "82-88", doi = "10.2298/SGS2202082P" }
Petrović, B., Krstić, M., Mudrinić, T., Čebela, M.,& Dutour-Sikirić, M.. (2022). Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid. in Stomatološki glasnik Srbije / Serbian Dental Journal, 69(2), 82-88. https://doi.org/10.2298/SGS2202082P
Petrović B, Krstić M, Mudrinić T, Čebela M, Dutour-Sikirić M. Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid. in Stomatološki glasnik Srbije / Serbian Dental Journal. 2022;69(2):82-88. doi:10.2298/SGS2202082P .
Petrović, Božana, Krstić, Maja, Mudrinić, Tihana, Čebela, Maria, Dutour-Sikirić, Maja, "Mg and Si substituted hydroxyapatite: Behaviour in simulated body fluid" in Stomatološki glasnik Srbije / Serbian Dental Journal, 69, no. 2 (2022):82-88, https://doi.org/10.2298/SGS2202082P . .