Effects of saline solution and simulated body fluid on ion substituted hydroxyapatites EPR spectra
Аутори
Vidotto, MonicaGrego, Timor
Erceg, Ina
Čolović, Božana M.
Dutour Sikirić, Maja
Maltar-Strmečk, Nadica
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Hydroxyapatite (HA, Ca10(PO4)6(OH)2), a calcium orthophosphate, due to its similarity to the inorganic part of human’s hard tissue, is among the most frequently used hard tissue regeneration biomaterial [1]. As such, the effects of HA ageing in media similar to blood plasma need to be studied, specifically after sterilization with γ-radiation, to better understand the possible structural changes it would undergo in the human body. Moreover, such changes in ion substituted HAs are particularly interesting since so called biological HA is in fact non-stoichiometric poorly crystalline, calcium deficient, Na-, Mg- and carbonate substituted HA (Dorozhkin, 2012) [2]. In this study, HA and 3 different substituted HAs were irradiated to 25 kGy with Co-60 γ-rays and their electron paramagnetic (EPR) spectra were recorded 1, 14 and 28 days after treatment with saline solution and simulated body fluid (SBF) [3]. The ion substituted HAs were doped with Mg and Si: 2% Mg; 2% Mg + 0.4% Si and 2% Mg +... 1.25% Si. EPR spectra were analysed, and the most pronounced peaks assigned. The effects of ageing in the two media are presented and discussed.
Извор:
RAD 2021 : 9th International Conference on Radiation in Various Fields of Research : book of abstracts; June 14-18; Herceg Novi, Montenegro, 2021, 12-Издавач:
- RAD Centre, Niš, Serbia
Финансирање / пројекти:
- Croatian-Serbian bilateral project “Ion substituted hydroxyapatites for bone tissue engineering”
- Croatian Science Foundation [ Grant HRZZ- IP-2018-01- 1493]
Напомена:
- IX International Conference on Radiation in Various Fields of Research : RAD 2021 : book of abstracts; June 14-18, 2021; Herceg Novi, Montenegro
Колекције
Институција/група
VinčaTY - CONF AU - Vidotto, Monica AU - Grego, Timor AU - Erceg, Ina AU - Čolović, Božana M. AU - Dutour Sikirić, Maja AU - Maltar-Strmečk, Nadica PY - 2021 UR - https://vinar.vin.bg.ac.rs/handle/123456789/11122 AB - Hydroxyapatite (HA, Ca10(PO4)6(OH)2), a calcium orthophosphate, due to its similarity to the inorganic part of human’s hard tissue, is among the most frequently used hard tissue regeneration biomaterial [1]. As such, the effects of HA ageing in media similar to blood plasma need to be studied, specifically after sterilization with γ-radiation, to better understand the possible structural changes it would undergo in the human body. Moreover, such changes in ion substituted HAs are particularly interesting since so called biological HA is in fact non-stoichiometric poorly crystalline, calcium deficient, Na-, Mg- and carbonate substituted HA (Dorozhkin, 2012) [2]. In this study, HA and 3 different substituted HAs were irradiated to 25 kGy with Co-60 γ-rays and their electron paramagnetic (EPR) spectra were recorded 1, 14 and 28 days after treatment with saline solution and simulated body fluid (SBF) [3]. The ion substituted HAs were doped with Mg and Si: 2% Mg; 2% Mg + 0.4% Si and 2% Mg + 1.25% Si. EPR spectra were analysed, and the most pronounced peaks assigned. The effects of ageing in the two media are presented and discussed. PB - RAD Centre, Niš, Serbia C3 - RAD 2021 : 9th International Conference on Radiation in Various Fields of Research : book of abstracts; June 14-18; Herceg Novi, Montenegro T1 - Effects of saline solution and simulated body fluid on ion substituted hydroxyapatites EPR spectra SP - 12 DO - 10.21175/rad.abstr.book.2021.4.3 ER -
@conference{ author = "Vidotto, Monica and Grego, Timor and Erceg, Ina and Čolović, Božana M. and Dutour Sikirić, Maja and Maltar-Strmečk, Nadica", year = "2021", abstract = "Hydroxyapatite (HA, Ca10(PO4)6(OH)2), a calcium orthophosphate, due to its similarity to the inorganic part of human’s hard tissue, is among the most frequently used hard tissue regeneration biomaterial [1]. As such, the effects of HA ageing in media similar to blood plasma need to be studied, specifically after sterilization with γ-radiation, to better understand the possible structural changes it would undergo in the human body. Moreover, such changes in ion substituted HAs are particularly interesting since so called biological HA is in fact non-stoichiometric poorly crystalline, calcium deficient, Na-, Mg- and carbonate substituted HA (Dorozhkin, 2012) [2]. In this study, HA and 3 different substituted HAs were irradiated to 25 kGy with Co-60 γ-rays and their electron paramagnetic (EPR) spectra were recorded 1, 14 and 28 days after treatment with saline solution and simulated body fluid (SBF) [3]. The ion substituted HAs were doped with Mg and Si: 2% Mg; 2% Mg + 0.4% Si and 2% Mg + 1.25% Si. EPR spectra were analysed, and the most pronounced peaks assigned. The effects of ageing in the two media are presented and discussed.", publisher = "RAD Centre, Niš, Serbia", journal = "RAD 2021 : 9th International Conference on Radiation in Various Fields of Research : book of abstracts; June 14-18; Herceg Novi, Montenegro", title = "Effects of saline solution and simulated body fluid on ion substituted hydroxyapatites EPR spectra", pages = "12", doi = "10.21175/rad.abstr.book.2021.4.3" }
Vidotto, M., Grego, T., Erceg, I., Čolović, B. M., Dutour Sikirić, M.,& Maltar-Strmečk, N.. (2021). Effects of saline solution and simulated body fluid on ion substituted hydroxyapatites EPR spectra. in RAD 2021 : 9th International Conference on Radiation in Various Fields of Research : book of abstracts; June 14-18; Herceg Novi, Montenegro RAD Centre, Niš, Serbia., 12. https://doi.org/10.21175/rad.abstr.book.2021.4.3
Vidotto M, Grego T, Erceg I, Čolović BM, Dutour Sikirić M, Maltar-Strmečk N. Effects of saline solution and simulated body fluid on ion substituted hydroxyapatites EPR spectra. in RAD 2021 : 9th International Conference on Radiation in Various Fields of Research : book of abstracts; June 14-18; Herceg Novi, Montenegro. 2021;:12. doi:10.21175/rad.abstr.book.2021.4.3 .
Vidotto, Monica, Grego, Timor, Erceg, Ina, Čolović, Božana M., Dutour Sikirić, Maja, Maltar-Strmečk, Nadica, "Effects of saline solution and simulated body fluid on ion substituted hydroxyapatites EPR spectra" in RAD 2021 : 9th International Conference on Radiation in Various Fields of Research : book of abstracts; June 14-18; Herceg Novi, Montenegro (2021):12, https://doi.org/10.21175/rad.abstr.book.2021.4.3 . .