TY  - JOUR
AU  - Jovanović, Svetlana P.
AU  - Marković, Zoran M.
AU  - Kleut, Duška
AU  - Romčević, Nebojša Ž.
AU  - Marinović-Cincović, Milena
AU  - Dramićanin, Miroslav
AU  - Todorović-Marković, Biljana
PY  - 2009
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3869
AB  - The results of synthesis and characterization of single wall carbon nanotubes functionalized by hydroxyethyl cellulose have been presented. The properties of pristine and modified single wall carbon nanotubes have been compared by different techniques: thermo-gravimetric analysis, Raman spectroscopy, Fourier transform infrared and UV-Vis-NIR spectroscopy. Raman analysis reveals that smaller amount of hydroxyethyl cellulose is required for functionalization of metallic single wall carbon nanotubes compared to semiconducting ones. FTIR analysis has shown the presence of hydroxyethyl groups which is strong evidence for nanotube modification.
T2  - Acta Chimica Slovenica
T1  - Functionalization of Single Wall Carbon Nanotubes by Hydroxyethyl Cellulose
VL  - 56
IS  - 4
SP  - 892
EP  - 899
UR  - https://hdl.handle.net/21.15107/rcub_vinar_3869
ER  - 

@article{
author = "Jovanović, Svetlana P. and Marković, Zoran M. and Kleut, Duška and Romčević, Nebojša Ž. and Marinović-Cincović, Milena and Dramićanin, Miroslav and Todorović-Marković, Biljana",
year = "2009",
abstract = "The results of synthesis and characterization of single wall carbon nanotubes functionalized by hydroxyethyl cellulose have been presented. The properties of pristine and modified single wall carbon nanotubes have been compared by different techniques: thermo-gravimetric analysis, Raman spectroscopy, Fourier transform infrared and UV-Vis-NIR spectroscopy. Raman analysis reveals that smaller amount of hydroxyethyl cellulose is required for functionalization of metallic single wall carbon nanotubes compared to semiconducting ones. FTIR analysis has shown the presence of hydroxyethyl groups which is strong evidence for nanotube modification.",
journal = "Acta Chimica Slovenica",
title = "Functionalization of Single Wall Carbon Nanotubes by Hydroxyethyl Cellulose",
volume = "56",
number = "4",
pages = "892-899",
url = "https://hdl.handle.net/21.15107/rcub_vinar_3869"
}

Jovanović, S. P., Marković, Z. M., Kleut, D., Romčević, N. Ž., Marinović-Cincović, M., Dramićanin, M.,& Todorović-Marković, B.. (2009). Functionalization of Single Wall Carbon Nanotubes by Hydroxyethyl Cellulose. in Acta Chimica Slovenica, 56(4), 892-899.
https://hdl.handle.net/21.15107/rcub_vinar_3869

Jovanović SP, Marković ZM, Kleut D, Romčević NŽ, Marinović-Cincović M, Dramićanin M, Todorović-Marković B. Functionalization of Single Wall Carbon Nanotubes by Hydroxyethyl Cellulose. in Acta Chimica Slovenica. 2009;56(4):892-899.
https://hdl.handle.net/21.15107/rcub_vinar_3869 .

Jovanović, Svetlana P., Marković, Zoran M., Kleut, Duška, Romčević, Nebojša Ž., Marinović-Cincović, Milena, Dramićanin, Miroslav, Todorović-Marković, Biljana, "Functionalization of Single Wall Carbon Nanotubes by Hydroxyethyl Cellulose" in Acta Chimica Slovenica, 56, no. 4 (2009):892-899,
https://hdl.handle.net/21.15107/rcub_vinar_3869 .

TY  - JOUR
AU  - Isaković, Aleksandra J.
AU  - Marković, Zoran M.
AU  - Todorović-Marković, Biljana
AU  - Nikolić, Nadežda S.
AU  - Vranješ-Đurić, Sanja
AU  - Mirković, Marija D.
AU  - Dramićanin, Miroslav
AU  - Harhaji, Ljubica M.
AU  - Raičević, Nevena
AU  - Nikolić, Zoran M.
AU  - Trajković, Vladimir S.
PY  - 2006
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3002
AB  - The mechanisms underlying the cytotoxic action of pure fullerene suspension (nano-C-60) and water-soluble polyhydroxylated fullerene [C-60(OH)(n)] were investigated. Crystal violet assay for cell viability demonstrated that nano-C-60 was at least three orders of magnitude more toxic than C-60(OH)(n) to mouse L929 fibrosarcoma, rat C6 glioma, and U251 human glioma cell lines. Flow cytometry analysis of cells stained with propidium iodide (PI), PI/annexin V-fluorescein isothiocyanate, or the redox-sensitive dye dihydrorhodamine revealed that nano-C-60 caused rapid (observable after few hours), reactive oxygen species (ROS)-associated necrosis characterized by cell membrane damage without DNA fragmentation. In contrast, C-60(OH)(n) caused delayed, ROS-independent cell death with characteristics of apoptosis, including DNA fragmentation and loss of cell membrane asymmetry in the absence of increased permeability. Accordingly, the antioxidant N-acetylcysteine protected the cell lines from nano-C-60 toxicity, but not C-60(OH)(n) toxicity, while the pan-caspase inhibitor z-VAD-fmk blocked C-60(OH)(n)-induced apoptosis, but not nano-C-60-mediated necrosis. Finally, C-60(OH)(n) antagonized, while nano-C-60 synergized with, the cytotoxic action of oxidative stress-inducing agents hydrogen peroxide and peroxynitrite donor 3-morpholinosydnonimine. Therefore, unlike polyhydroxylated C-60 that exerts mainly antioxidant/cytoprotective and only mild ROS-independent pro-apoptotic activity, pure crystalline C-60 seems to be endowed with strong pro-oxidant capacity responsible for the rapid necrotic cell death.
T2  - Toxicological Sciences
T1  - Distinct cytotoxic mechanisms of pristine versus hydroxylated fullerene
VL  - 91
IS  - 1
SP  - 173
EP  - 183
DO  - 10.1093/toxsci/kfj127
ER  - 

@article{
author = "Isaković, Aleksandra J. and Marković, Zoran M. and Todorović-Marković, Biljana and Nikolić, Nadežda S. and Vranješ-Đurić, Sanja and Mirković, Marija D. and Dramićanin, Miroslav and Harhaji, Ljubica M. and Raičević, Nevena and Nikolić, Zoran M. and Trajković, Vladimir S.",
year = "2006",
abstract = "The mechanisms underlying the cytotoxic action of pure fullerene suspension (nano-C-60) and water-soluble polyhydroxylated fullerene [C-60(OH)(n)] were investigated. Crystal violet assay for cell viability demonstrated that nano-C-60 was at least three orders of magnitude more toxic than C-60(OH)(n) to mouse L929 fibrosarcoma, rat C6 glioma, and U251 human glioma cell lines. Flow cytometry analysis of cells stained with propidium iodide (PI), PI/annexin V-fluorescein isothiocyanate, or the redox-sensitive dye dihydrorhodamine revealed that nano-C-60 caused rapid (observable after few hours), reactive oxygen species (ROS)-associated necrosis characterized by cell membrane damage without DNA fragmentation. In contrast, C-60(OH)(n) caused delayed, ROS-independent cell death with characteristics of apoptosis, including DNA fragmentation and loss of cell membrane asymmetry in the absence of increased permeability. Accordingly, the antioxidant N-acetylcysteine protected the cell lines from nano-C-60 toxicity, but not C-60(OH)(n) toxicity, while the pan-caspase inhibitor z-VAD-fmk blocked C-60(OH)(n)-induced apoptosis, but not nano-C-60-mediated necrosis. Finally, C-60(OH)(n) antagonized, while nano-C-60 synergized with, the cytotoxic action of oxidative stress-inducing agents hydrogen peroxide and peroxynitrite donor 3-morpholinosydnonimine. Therefore, unlike polyhydroxylated C-60 that exerts mainly antioxidant/cytoprotective and only mild ROS-independent pro-apoptotic activity, pure crystalline C-60 seems to be endowed with strong pro-oxidant capacity responsible for the rapid necrotic cell death.",
journal = "Toxicological Sciences",
title = "Distinct cytotoxic mechanisms of pristine versus hydroxylated fullerene",
volume = "91",
number = "1",
pages = "173-183",
doi = "10.1093/toxsci/kfj127"
}

Isaković, A. J., Marković, Z. M., Todorović-Marković, B., Nikolić, N. S., Vranješ-Đurić, S., Mirković, M. D., Dramićanin, M., Harhaji, L. M., Raičević, N., Nikolić, Z. M.,& Trajković, V. S.. (2006). Distinct cytotoxic mechanisms of pristine versus hydroxylated fullerene. in Toxicological Sciences, 91(1), 173-183.
https://doi.org/10.1093/toxsci/kfj127

Isaković AJ, Marković ZM, Todorović-Marković B, Nikolić NS, Vranješ-Đurić S, Mirković MD, Dramićanin M, Harhaji LM, Raičević N, Nikolić ZM, Trajković VS. Distinct cytotoxic mechanisms of pristine versus hydroxylated fullerene. in Toxicological Sciences. 2006;91(1):173-183.
doi:10.1093/toxsci/kfj127 .

Isaković, Aleksandra J., Marković, Zoran M., Todorović-Marković, Biljana, Nikolić, Nadežda S., Vranješ-Đurić, Sanja, Mirković, Marija D., Dramićanin, Miroslav, Harhaji, Ljubica M., Raičević, Nevena, Nikolić, Zoran M., Trajković, Vladimir S., "Distinct cytotoxic mechanisms of pristine versus hydroxylated fullerene" in Toxicological Sciences, 91, no. 1 (2006):173-183,
https://doi.org/10.1093/toxsci/kfj127 . .