TY  - JOUR
AU  - Bajić, Vladan P.
AU  - Stanimirovic, Z.
AU  - Stevanović, Jevrosima
AU  - Milićević, Zorka T.
AU  - Živković, Lada
AU  - Spremo-Potparević, Biljana
PY  - 2010
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3998
AB  - Premature centromere division (PCD) can be viewed as a manifestation of chromosome instability. In order to evaluate the ability of Paclitaxel (Ptx) and Cycloheximide (Cy) to induce PCD we used a cytokinesis block micronucleus assay (CBMN), fluorescent in situ hybridization (FISH), and the chromosome aberration (CA) assay in human peripheral blood lymphocytes. Results showed that Ptx can induce PCD alone or in combination with Cy. These findings call us to pay more attention to PCD as a parameter of genotoxicity in the pre-clinical research of mono- and/or combinational therapies for cancer treatment.
T2  - Archives of Biological Sciences
T1  - The Effect of Paclitaxel Alone and in Combination with Cycloheximide on the Frequency of Premature Centromere Division in Vitro
VL  - 62
IS  - 1
SP  - 63
EP  - 74
DO  - 10.2298/ABS1001063B
ER  - 

@article{
author = "Bajić, Vladan P. and Stanimirovic, Z. and Stevanović, Jevrosima and Milićević, Zorka T. and Živković, Lada and Spremo-Potparević, Biljana",
year = "2010",
abstract = "Premature centromere division (PCD) can be viewed as a manifestation of chromosome instability. In order to evaluate the ability of Paclitaxel (Ptx) and Cycloheximide (Cy) to induce PCD we used a cytokinesis block micronucleus assay (CBMN), fluorescent in situ hybridization (FISH), and the chromosome aberration (CA) assay in human peripheral blood lymphocytes. Results showed that Ptx can induce PCD alone or in combination with Cy. These findings call us to pay more attention to PCD as a parameter of genotoxicity in the pre-clinical research of mono- and/or combinational therapies for cancer treatment.",
journal = "Archives of Biological Sciences",
title = "The Effect of Paclitaxel Alone and in Combination with Cycloheximide on the Frequency of Premature Centromere Division in Vitro",
volume = "62",
number = "1",
pages = "63-74",
doi = "10.2298/ABS1001063B"
}

Bajić, V. P., Stanimirovic, Z., Stevanović, J., Milićević, Z. T., Živković, L.,& Spremo-Potparević, B.. (2010). The Effect of Paclitaxel Alone and in Combination with Cycloheximide on the Frequency of Premature Centromere Division in Vitro. in Archives of Biological Sciences, 62(1), 63-74.
https://doi.org/10.2298/ABS1001063B

Bajić VP, Stanimirovic Z, Stevanović J, Milićević ZT, Živković L, Spremo-Potparević B. The Effect of Paclitaxel Alone and in Combination with Cycloheximide on the Frequency of Premature Centromere Division in Vitro. in Archives of Biological Sciences. 2010;62(1):63-74.
doi:10.2298/ABS1001063B .

Bajić, Vladan P., Stanimirovic, Z., Stevanović, Jevrosima, Milićević, Zorka T., Živković, Lada, Spremo-Potparević, Biljana, "The Effect of Paclitaxel Alone and in Combination with Cycloheximide on the Frequency of Premature Centromere Division in Vitro" in Archives of Biological Sciences, 62, no. 1 (2010):63-74,
https://doi.org/10.2298/ABS1001063B . .