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Nikolić, Dragana

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  • Nikolić, Dragana (11)
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Author's Bibliography

Comparison of Radiation Characteristics of HfO2 and SiO2 Incorporated in MOS Capacitor in Field of Gamma and X Radiation

Stanković, Srboljub J.; Nikolić, Dragana; Kržanović, Nikola; Nađđerđ, Laslo; Davidović, Vojkan S.

(IEEE, 2019)

TY  - CONF
AU  - Stanković, Srboljub J.
AU  - Nikolić, Dragana
AU  - Kržanović, Nikola
AU  - Nađđerđ, Laslo
AU  - Davidović, Vojkan S.
PY  - 2019
UR  - https://ieeexplore.ieee.org/document/8889613/
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/8659
AB  - The paper presents the application of a numerical method for the determination of the absorbed dose rate of gamma and X radiation in the dielectric thin layer of hafnium dioxide (RfO2) or SiO2, which is located in the structure of the MOS capacitor. Considering the radiation characteristics of the selected dielectrics, it can be concluded that there are advantages of RfO2 over SiO2 in the radiation field with high-energy X-rays. Similar radiation effects should be expected for the interaction of dielectric material with gamma ray photons originating from a Co-60 source, both in the dielectric layer with SiO2 and in that with RfO2. It can be concluded that for the same radiation absorbed dose into the MOS capacitor with RfO2, there are a greater number of generated electron-hole pairs, in which case the value of effective trapping efficiency is smaller than if SiO2 was used. © 2019 IEEE.
PB  - IEEE
C3  - 2019 IEEE 31st International Conference on Microelectronics (MIEL)
T1  - Comparison of Radiation Characteristics of HfO2 and SiO2 Incorporated in MOS Capacitor in Field of Gamma and X Radiation
SP  - 181
EP  - 184
DO  - 10.1109/MIEL.2019.8889613
ER  - 
@conference{
author = "Stanković, Srboljub J. and Nikolić, Dragana and Kržanović, Nikola and Nađđerđ, Laslo and Davidović, Vojkan S.",
year = "2019",
url = "https://ieeexplore.ieee.org/document/8889613/, http://vinar.vin.bg.ac.rs/handle/123456789/8659",
abstract = "The paper presents the application of a numerical method for the determination of the absorbed dose rate of gamma and X radiation in the dielectric thin layer of hafnium dioxide (RfO2) or SiO2, which is located in the structure of the MOS capacitor. Considering the radiation characteristics of the selected dielectrics, it can be concluded that there are advantages of RfO2 over SiO2 in the radiation field with high-energy X-rays. Similar radiation effects should be expected for the interaction of dielectric material with gamma ray photons originating from a Co-60 source, both in the dielectric layer with SiO2 and in that with RfO2. It can be concluded that for the same radiation absorbed dose into the MOS capacitor with RfO2, there are a greater number of generated electron-hole pairs, in which case the value of effective trapping efficiency is smaller than if SiO2 was used. © 2019 IEEE.",
publisher = "IEEE",
journal = "2019 IEEE 31st International Conference on Microelectronics (MIEL)",
title = "Comparison of Radiation Characteristics of HfO2 and SiO2 Incorporated in MOS Capacitor in Field of Gamma and X Radiation",
pages = "181-184",
doi = "10.1109/MIEL.2019.8889613"
}

Liraglutide Reduces Oxidative Stress And Restores Heme Oxygenase-1 and Ghrelin Levels in Patients with Type 2 Diabetes: A Prospective Pilot Study

Rizzo, Manfredi; Abate, Nicola; Chandalia, Manisha; Rizvi, Ali A.; Giglio, Rosaria V.; Nikolić, Dragana; Gammazza, Antonella Marino; Barbagallo, Ignazio; Isenović, Esma R.; Banach, Maciej; Montalto, Giuseppe; Volti, Giovanni Li

(2015)

TY  - JOUR
AU  - Rizzo, Manfredi
AU  - Abate, Nicola
AU  - Chandalia, Manisha
AU  - Rizvi, Ali A.
AU  - Giglio, Rosaria V.
AU  - Nikolić, Dragana
AU  - Gammazza, Antonella Marino
AU  - Barbagallo, Ignazio
AU  - Isenović, Esma R.
AU  - Banach, Maciej
AU  - Montalto, Giuseppe
AU  - Volti, Giovanni Li
PY  - 2015
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/508
AB  - Context: Liraglutide is a glucagon-like peptide-1 analog and glucose-lowering agent whose effects on cardiovascular risk markers have not been fully elucidated. Objective: We evaluated the effect of liraglutide on markers of oxidative stress, heme oxygenase-1 (HO-1), and plasma ghrelin levels in patients with type-2 diabetes mellitus (T2DM). Design and Setting: A prospective pilot study of 2 months duration has been performed at the Unit of Diabetes and Cardiovascular Prevention at University of Palermo, Italy. Patients and Intervention(s): Twenty subjects with T2DM (10 men and 10 women; meanage: 57 +/- 13 y) were treated with liraglutide sc (0.6 mg/d for 2 wk, followed by 1.2 mg/d) in addition to metformin (1500 mg/d orally) for 2 months. Patients with liver disorders or renal failure were excluded. Main Outcome Measure(s): Plasma ghrelin concentrations, oxidative stress markers, and heat-shock proteins, including HO-1 were assessed. Results: The addition of liraglutide resulted in a significant decrease in glycated hemoglobin (HbA1c) (8.5 +/- 0.4 vs 7.5 +/- 0.4%, P LT .0001). In addition, plasma ghrelin and glutathione concentrations increased (8.2 +/- 4.1 vs 13.6 +/- 7.3 pg/ml, P = .0007 and 0.36 +/- 0.06 vs 0.44 +/- 0.07 nmol/ml, P = .0002, respectively), whereas serum lipid hydroperoxides and HO-1 decreased (0.11 +/- 0.05 vs 0.04 +/- 0.07 pg/ml, P = .0487 and 7.7 +/- 7.7 vs 3.6 +/- 1.8 pg/ml, P = .0445, respectively). These changes were not correlated with changes in fasting glycemia or HbA1c. Conclusions: In a 2-months prospective pilot study, the addition of liraglutide to metformin resulted in improvement in oxidative stress as well as plasma ghrelin and HO-1 concentrations in patients with T2DM. These findings seemed to be independent of the known effects of liraglutide on glucose metabolism.
T2  - Journal of Clinical Endocrinology and Metabolism
T1  - Liraglutide Reduces Oxidative Stress And Restores Heme Oxygenase-1 and Ghrelin Levels in Patients with Type 2 Diabetes: A Prospective Pilot Study
VL  - 100
IS  - 2
SP  - 603
EP  - 606
DO  - 10.1210/jc.2014-2291
ER  - 
@article{
author = "Rizzo, Manfredi and Abate, Nicola and Chandalia, Manisha and Rizvi, Ali A. and Giglio, Rosaria V. and Nikolić, Dragana and Gammazza, Antonella Marino and Barbagallo, Ignazio and Isenović, Esma R. and Banach, Maciej and Montalto, Giuseppe and Volti, Giovanni Li",
year = "2015",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/508",
abstract = "Context: Liraglutide is a glucagon-like peptide-1 analog and glucose-lowering agent whose effects on cardiovascular risk markers have not been fully elucidated. Objective: We evaluated the effect of liraglutide on markers of oxidative stress, heme oxygenase-1 (HO-1), and plasma ghrelin levels in patients with type-2 diabetes mellitus (T2DM). Design and Setting: A prospective pilot study of 2 months duration has been performed at the Unit of Diabetes and Cardiovascular Prevention at University of Palermo, Italy. Patients and Intervention(s): Twenty subjects with T2DM (10 men and 10 women; meanage: 57 +/- 13 y) were treated with liraglutide sc (0.6 mg/d for 2 wk, followed by 1.2 mg/d) in addition to metformin (1500 mg/d orally) for 2 months. Patients with liver disorders or renal failure were excluded. Main Outcome Measure(s): Plasma ghrelin concentrations, oxidative stress markers, and heat-shock proteins, including HO-1 were assessed. Results: The addition of liraglutide resulted in a significant decrease in glycated hemoglobin (HbA1c) (8.5 +/- 0.4 vs 7.5 +/- 0.4%, P LT .0001). In addition, plasma ghrelin and glutathione concentrations increased (8.2 +/- 4.1 vs 13.6 +/- 7.3 pg/ml, P = .0007 and 0.36 +/- 0.06 vs 0.44 +/- 0.07 nmol/ml, P = .0002, respectively), whereas serum lipid hydroperoxides and HO-1 decreased (0.11 +/- 0.05 vs 0.04 +/- 0.07 pg/ml, P = .0487 and 7.7 +/- 7.7 vs 3.6 +/- 1.8 pg/ml, P = .0445, respectively). These changes were not correlated with changes in fasting glycemia or HbA1c. Conclusions: In a 2-months prospective pilot study, the addition of liraglutide to metformin resulted in improvement in oxidative stress as well as plasma ghrelin and HO-1 concentrations in patients with T2DM. These findings seemed to be independent of the known effects of liraglutide on glucose metabolism.",
journal = "Journal of Clinical Endocrinology and Metabolism",
title = "Liraglutide Reduces Oxidative Stress And Restores Heme Oxygenase-1 and Ghrelin Levels in Patients with Type 2 Diabetes: A Prospective Pilot Study",
volume = "100",
number = "2",
pages = "603-606",
doi = "10.1210/jc.2014-2291"
}
7
48
56
59

Uric Acid Metabolism in Pre-hypertension and the Metabolic Syndrome

Rizzo, Manfredi; Obradović, Milan M.; Labudović-Borović, Milica; Nikolić, Dragana; Montalto, Giuseppe; Rizvi, Ali A.; Mikhailidis, Dimitri P.; Isenović, Esma R.

(2014)

TY  - JOUR
AU  - Rizzo, Manfredi
AU  - Obradović, Milan M.
AU  - Labudović-Borović, Milica
AU  - Nikolić, Dragana
AU  - Montalto, Giuseppe
AU  - Rizvi, Ali A.
AU  - Mikhailidis, Dimitri P.
AU  - Isenović, Esma R.
PY  - 2014
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/290
AB  - In humans uric acid (UA) is the end product of degradation of purines. The handling of UA by the renal system is a complex process which is not fully understood. To date, several urate transporters in the renal proximal tubule have been identified. Among them, urate transporter 1 (URAT1) and a glucose transporter 9 (GLUT9) are considered of greater importance, as potential targets for treatment of hyperuricemia and the potential associated cardio-metabolic risk. Therefore, the recognition of the metabolic pathway of UA and elucidation of occurrence of hyperuricemia may provide important insights about the relationship between UA, pre-hypertension (preHT) and the metabolic syndrome (MetS). We also review the available clinical studies in this field, including experimental studies dealing with the mechanisms of UA transport via different transporters, as well as current treatment options for hyperuricemia in patients with MetS, preHT or cardiovascular risk factors.
T2  - Current Vascular Pharmacology
T1  - Uric Acid Metabolism in Pre-hypertension and the Metabolic Syndrome
VL  - 12
IS  - 4
SP  - 572
EP  - 585
DO  - 10.2174/1570161111999131205160756
ER  - 
@article{
author = "Rizzo, Manfredi and Obradović, Milan M. and Labudović-Borović, Milica and Nikolić, Dragana and Montalto, Giuseppe and Rizvi, Ali A. and Mikhailidis, Dimitri P. and Isenović, Esma R.",
year = "2014",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/290",
abstract = "In humans uric acid (UA) is the end product of degradation of purines. The handling of UA by the renal system is a complex process which is not fully understood. To date, several urate transporters in the renal proximal tubule have been identified. Among them, urate transporter 1 (URAT1) and a glucose transporter 9 (GLUT9) are considered of greater importance, as potential targets for treatment of hyperuricemia and the potential associated cardio-metabolic risk. Therefore, the recognition of the metabolic pathway of UA and elucidation of occurrence of hyperuricemia may provide important insights about the relationship between UA, pre-hypertension (preHT) and the metabolic syndrome (MetS). We also review the available clinical studies in this field, including experimental studies dealing with the mechanisms of UA transport via different transporters, as well as current treatment options for hyperuricemia in patients with MetS, preHT or cardiovascular risk factors.",
journal = "Current Vascular Pharmacology",
title = "Uric Acid Metabolism in Pre-hypertension and the Metabolic Syndrome",
volume = "12",
number = "4",
pages = "572-585",
doi = "10.2174/1570161111999131205160756"
}
13
15
17

Resistin: An Inflammatory Cytokine. Role in Cardiovascular Diseases, Diabetes and the Metabolic Syndrome

Abate, Nicola; Sallam, Hanaa S.; Rizzo, Manfredi; Nikolić, Dragana; Obradović, Milan M.; Bjelogrlic, Predrag; Isenović, Esma R.

(2014)

TY  - JOUR
AU  - Abate, Nicola
AU  - Sallam, Hanaa S.
AU  - Rizzo, Manfredi
AU  - Nikolić, Dragana
AU  - Obradović, Milan M.
AU  - Bjelogrlic, Predrag
AU  - Isenović, Esma R.
PY  - 2014
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/56
AB  - Resistin is an adipocyte-and monocyte-derived cytokine which has been implicated in the modulation of insulin action, energy, glucose and lipid homeostasis. Resistin has been associated with insulin resistance and many of its known complications. As a molecular link between metabolic signals, inflammation, and vascular dysfunction, resistin can be proposed as playing a significant role in the heightened inflammatory state induced by metabolic stress linked to excessive caloric intake, thus contributing to the risk for metabolic syndrome (MetS), type 2 diabetes (T2DM), and cardiovascular diseases (CVD). In this review, we highlighted the role of resistin, as an inflammatory cytokine, in the development of CVD, T2DM and the MetS.
T2  - Current Pharmaceutical Design
T1  - Resistin: An Inflammatory Cytokine. Role in Cardiovascular Diseases, Diabetes and the Metabolic Syndrome
VL  - 20
IS  - 31
SP  - 4961
EP  - 4969
ER  - 
@article{
author = "Abate, Nicola and Sallam, Hanaa S. and Rizzo, Manfredi and Nikolić, Dragana and Obradović, Milan M. and Bjelogrlic, Predrag and Isenović, Esma R.",
year = "2014",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/56",
abstract = "Resistin is an adipocyte-and monocyte-derived cytokine which has been implicated in the modulation of insulin action, energy, glucose and lipid homeostasis. Resistin has been associated with insulin resistance and many of its known complications. As a molecular link between metabolic signals, inflammation, and vascular dysfunction, resistin can be proposed as playing a significant role in the heightened inflammatory state induced by metabolic stress linked to excessive caloric intake, thus contributing to the risk for metabolic syndrome (MetS), type 2 diabetes (T2DM), and cardiovascular diseases (CVD). In this review, we highlighted the role of resistin, as an inflammatory cytokine, in the development of CVD, T2DM and the MetS.",
journal = "Current Pharmaceutical Design",
title = "Resistin: An Inflammatory Cytokine. Role in Cardiovascular Diseases, Diabetes and the Metabolic Syndrome",
volume = "20",
number = "31",
pages = "4961-4969"
}
36

Lipoprotein Subfractions in Metabolic Syndrome and Obesity: Clinical Significance and Therapeutic Approaches

Nikolić, Dragana; Katsiki, Niki; Montalto, Giuseppe; Isenović, Esma R.; Mikhailidis, Dimitri P.; Rizzo, Manfredi

(2013)

@article{
author = "Nikolić, Dragana and Katsiki, Niki and Montalto, Giuseppe and Isenović, Esma R. and Mikhailidis, Dimitri P. and Rizzo, Manfredi",
year = "2013",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/5380",
abstract = "Small, dense low density lipoprotein (sdLDL) represents an emerging cardiovascular risk factor, since these particles can be associated with cardiovascular disease (CVD) independently of established risk factors, including plasma lipids. Obese subjects frequently have atherogenic dyslipidaemia, including elevated sdLDL levels, in addition to elevated triglycerides (TG), very low density lipoprotein (VLDL) and apolipoprotein-B, as well as decreased high density lipoprotein cholesterol (HDL-C) levels. Obesity-related co-morbidities, such as metabolic syndrome (MetS) are also characterized by dyslipidaemia. Therefore, agents that favourably modulate LDL subclasses may be of clinical value in these subjects. Statins are the lipid-lowering drug of choice. Also, anti-obesity and lipid lowering drugs other than statins could be useful in these patients. However, the effects of anti-obesity drugs on CVD risk factors remain unclear. We review the clinical significance of sdLDL in being overweight and obesity, as well as the efficacy of anti-obesity drugs on LDL subfractions in these individuals; a short comment on HDL subclasses is also included. Our literature search was based on PubMed and Scopus listings. Further research is required to fully explore both the significance of sdLDL and the efficacy of anti-obesity drugs on LDL subfractions in being overweight, obesity and MetS. Improving the lipoprotein profile in these patients may represent an efficient approach for reducing cardiovascular risk.",
journal = "Nutrients",
title = "Lipoprotein Subfractions in Metabolic Syndrome and Obesity: Clinical Significance and Therapeutic Approaches",
volume = "5",
number = "3",
pages = "928-948",
doi = "10.3390/nu5030928"
}
11
74
93
95

Preparation and properties of porous, biomorphic, ceria ceramics for immobilization of Sr isotopes

Matović, Branko; Nikolić, Dragana; Labus, N.; Ilić, Svetlana M.; Maksimović, Vesna; Luković, Jelena M.; Bučevac, Dušan

(2013)

TY  - JOUR
AU  - Matović, Branko
AU  - Nikolić, Dragana
AU  - Labus, N.
AU  - Ilić, Svetlana M.
AU  - Maksimović, Vesna
AU  - Luković, Jelena M.
AU  - Bučevac, Dušan
PY  - 2013
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/5722
AB  - A new technology for radionuclide trapping which is based on bio-templating approach was proposed in this paper. Porous oxide ceramics was prepared by wet impregnation of biological template with water solution of cerium and strontium nitrates. The template was derived from linden wood (tilia amurensis). Repeated pressure impregnation, heat treatments and final calcination at 1000 degrees C in air resulted in the template burnout and consolidation of the oxide layers. The obtained products had structure which corresponded to the negative replication of biological templates. X-ray diffraction, scanning electron microscopy, Raman spectroscopy and porosimetry were employed to characterize the composition and structure of biomorphic ceramics. It was found that the wood impregnated with water solution of cerium and strontium nitrates was converted into oxide ceramics (Ce0.9Sr0.1O2-delta), while preserving the microstructural features of the biological preform. (C) 2013 Elsevier Ltd and Techna Group S.r.l. All rights reserved.
T2  - Ceramics International
T1  - Preparation and properties of porous, biomorphic, ceria ceramics for immobilization of Sr isotopes
VL  - 39
IS  - 8
SP  - 9645
EP  - 9649
DO  - 10.1016/j.ceramint.2013.05.086
ER  - 
@article{
author = "Matović, Branko and Nikolić, Dragana and Labus, N. and Ilić, Svetlana M. and Maksimović, Vesna and Luković, Jelena M. and Bučevac, Dušan",
year = "2013",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/5722",
abstract = "A new technology for radionuclide trapping which is based on bio-templating approach was proposed in this paper. Porous oxide ceramics was prepared by wet impregnation of biological template with water solution of cerium and strontium nitrates. The template was derived from linden wood (tilia amurensis). Repeated pressure impregnation, heat treatments and final calcination at 1000 degrees C in air resulted in the template burnout and consolidation of the oxide layers. The obtained products had structure which corresponded to the negative replication of biological templates. X-ray diffraction, scanning electron microscopy, Raman spectroscopy and porosimetry were employed to characterize the composition and structure of biomorphic ceramics. It was found that the wood impregnated with water solution of cerium and strontium nitrates was converted into oxide ceramics (Ce0.9Sr0.1O2-delta), while preserving the microstructural features of the biological preform. (C) 2013 Elsevier Ltd and Techna Group S.r.l. All rights reserved.",
journal = "Ceramics International",
title = "Preparation and properties of porous, biomorphic, ceria ceramics for immobilization of Sr isotopes",
volume = "39",
number = "8",
pages = "9645-9649",
doi = "10.1016/j.ceramint.2013.05.086"
}
6
6
6

Effect of Low Temperature Cultivation on Insulin Secretory of Human Pancreatic Islets

Nikolić, Dragana; Djordjevic, P. B.; Lackovic, V. B.; Stojiljković, Vesna; Stanojević, Boban

(2013)

TY  - JOUR
AU  - Nikolić, Dragana
AU  - Djordjevic, P. B.
AU  - Lackovic, V. B.
AU  - Stojiljković, Vesna
AU  - Stanojević, Boban
PY  - 2013
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/5409
AB  - The experiment compared the physiological function (insulin secretory capacity) and membrane integrity of human adult pancreatic islets incubated in culture at 37 degrees C and 24 degrees C. Pancreatic tissue was digested with Collagenase XI, using a non-automated method. Cultures were incubated at 37 degrees C and 24 degrees C. Secretory capacity of the islets is determined by measuring of the stimulation index (SI) on the 3rd and 7th day of cultivation. Membrane integrity of the islets was determined by dithizone staining. Both groups of examined cultures show a slight increase in SI during the incubation. However islets incubated at 24 degrees C show higher SI values than those incubated at 37 degrees C on the 1st, 3rd and 7th day of incubation. And on the first day of incubation, this difference was statistically significant (p LT 0.05). Islets incubated at 37 degrees C showed preservation of membrane integrity, the islets are regular spherical shape, while those incubated at 24 degrees C lose such an organization. During the seven-day cultivation, islets incubated at a standard temperature of 37 degrees C show less preserve physiological functions in relation to cultures incubated at 24 degrees C, but islets incubated at 37 degrees C show more regular morphological forms.
T2  - Journal of Biological Regulators and Homeostatic Agents
T1  - Effect of Low Temperature Cultivation on Insulin Secretory of Human Pancreatic Islets
VL  - 27
IS  - 1
SP  - 35
EP  - 44
ER  - 
@article{
author = "Nikolić, Dragana and Djordjevic, P. B. and Lackovic, V. B. and Stojiljković, Vesna and Stanojević, Boban",
year = "2013",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/5409",
abstract = "The experiment compared the physiological function (insulin secretory capacity) and membrane integrity of human adult pancreatic islets incubated in culture at 37 degrees C and 24 degrees C. Pancreatic tissue was digested with Collagenase XI, using a non-automated method. Cultures were incubated at 37 degrees C and 24 degrees C. Secretory capacity of the islets is determined by measuring of the stimulation index (SI) on the 3rd and 7th day of cultivation. Membrane integrity of the islets was determined by dithizone staining. Both groups of examined cultures show a slight increase in SI during the incubation. However islets incubated at 24 degrees C show higher SI values than those incubated at 37 degrees C on the 1st, 3rd and 7th day of incubation. And on the first day of incubation, this difference was statistically significant (p LT 0.05). Islets incubated at 37 degrees C showed preservation of membrane integrity, the islets are regular spherical shape, while those incubated at 24 degrees C lose such an organization. During the seven-day cultivation, islets incubated at a standard temperature of 37 degrees C show less preserve physiological functions in relation to cultures incubated at 24 degrees C, but islets incubated at 37 degrees C show more regular morphological forms.",
journal = "Journal of Biological Regulators and Homeostatic Agents",
title = "Effect of Low Temperature Cultivation on Insulin Secretory of Human Pancreatic Islets",
volume = "27",
number = "1",
pages = "35-44"
}
1

Msv Signal Processing System for Neutron-Gamma Discrimination in a Mixed Field

Stanković, Srboljub J.; Iricanin, Bratislav D.; Nikolić, Dragana; Janković, Ksenija S.; Radenković, Mirjana; Stankovic, Koviljka D. J.; Osmokrovic, Predrag V.

(2012)

TY  - JOUR
AU  - Stanković, Srboljub J.
AU  - Iricanin, Bratislav D.
AU  - Nikolić, Dragana
AU  - Janković, Ksenija S.
AU  - Radenković, Mirjana
AU  - Stankovic, Koviljka D. J.
AU  - Osmokrovic, Predrag V.
PY  - 2012
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/4928
AB  - Based on the principles derived from Campbells theorem, this paper carries out an analysis of the possibilities of Campbells mean square value signal processing system. The mean square value mode is especially suitable for measurements performed in a mixed radiation field, because the quantities of electrical charge involved in the interactions of the two types of radiation are substantially different. The measuring detector element may be an adequate ionization chamber and/or semiconductor components for mixed n-gamma fields. An examination of the discrimination of gamma in relation to the neutron component in the signal of the detector output was carried out, calculated according to the theoretical model of radiation interaction with the detector. The advantage of the mean square value method was confirmed and it was concluded that the order of n-gamma discrimination in mean square value signal processing is greater than the one rendered by the classical measuring method.
T2  - Nuclear technology and radiation protection
T1  - Msv Signal Processing System for Neutron-Gamma Discrimination in a Mixed Field
VL  - 27
IS  - 2
SP  - 165
EP  - 170
DO  - 10.2298/NTRP1202165S
ER  - 
@article{
author = "Stanković, Srboljub J. and Iricanin, Bratislav D. and Nikolić, Dragana and Janković, Ksenija S. and Radenković, Mirjana and Stankovic, Koviljka D. J. and Osmokrovic, Predrag V.",
year = "2012",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/4928",
abstract = "Based on the principles derived from Campbells theorem, this paper carries out an analysis of the possibilities of Campbells mean square value signal processing system. The mean square value mode is especially suitable for measurements performed in a mixed radiation field, because the quantities of electrical charge involved in the interactions of the two types of radiation are substantially different. The measuring detector element may be an adequate ionization chamber and/or semiconductor components for mixed n-gamma fields. An examination of the discrimination of gamma in relation to the neutron component in the signal of the detector output was carried out, calculated according to the theoretical model of radiation interaction with the detector. The advantage of the mean square value method was confirmed and it was concluded that the order of n-gamma discrimination in mean square value signal processing is greater than the one rendered by the classical measuring method.",
journal = "Nuclear technology and radiation protection",
title = "Msv Signal Processing System for Neutron-Gamma Discrimination in a Mixed Field",
volume = "27",
number = "2",
pages = "165-170",
doi = "10.2298/NTRP1202165S"
}
5
11
11

Peroxisome Proliferator-Activated Receptors and Atherosclerosis

Soskić, Sanja S.; Dobutovic, Branislava D.; Sudar, Emina; Obradović, Milan M.; Nikolić, Dragana; Zarić, Božidarka; Stojanovic, Srdan D.; Stokić, Edita; Mikhailidis, Dimitri P.; Isenović, Esma R.

(2011)

TY  - JOUR
AU  - Soskić, Sanja S.
AU  - Dobutovic, Branislava D.
AU  - Sudar, Emina
AU  - Obradović, Milan M.
AU  - Nikolić, Dragana
AU  - Zarić, Božidarka
AU  - Stojanovic, Srdan D.
AU  - Stokić, Edita
AU  - Mikhailidis, Dimitri P.
AU  - Isenović, Esma R.
PY  - 2011
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/4519
AB  - The peroxisome proliferator-activated receptors (PPARs) represent the family of 3 nuclear receptor isoforms-PPAR alpha, -gamma, and -delta/beta, which are encoded by different genes. As lipid sensors, they are primarily involved in regulation of lipid metabolism and subsequently in inflammation and atherosclerosis. Atherosclerosis considers accumulation of the cells and extracellular matrix in the vessel wall leading to the formation of atherosclerotic plaque, atherothrombosis, and other vascular complications. Besides existence of natural ligands for PPARs, their more potent synthetic ligands are fibrates and thiazolidindiones. Future investigations should now focus on the mechanisms of PPARs activation, which might present new approaches involved in the antiatherosclerotic effects revealed in this review. In addition, in this review we are presenting latest data from recent performed clinical studies which have focus on novel approach to PPARs agonists as potential therapeutic agents in the treatment of complex disease such as atherosclerosis.
T2  - Angiology
T1  - Peroxisome Proliferator-Activated Receptors and Atherosclerosis
VL  - 62
IS  - 7
SP  - 523
EP  - 534
DO  - 10.1177/0003319711401012
ER  - 
@article{
author = "Soskić, Sanja S. and Dobutovic, Branislava D. and Sudar, Emina and Obradović, Milan M. and Nikolić, Dragana and Zarić, Božidarka and Stojanovic, Srdan D. and Stokić, Edita and Mikhailidis, Dimitri P. and Isenović, Esma R.",
year = "2011",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/4519",
abstract = "The peroxisome proliferator-activated receptors (PPARs) represent the family of 3 nuclear receptor isoforms-PPAR alpha, -gamma, and -delta/beta, which are encoded by different genes. As lipid sensors, they are primarily involved in regulation of lipid metabolism and subsequently in inflammation and atherosclerosis. Atherosclerosis considers accumulation of the cells and extracellular matrix in the vessel wall leading to the formation of atherosclerotic plaque, atherothrombosis, and other vascular complications. Besides existence of natural ligands for PPARs, their more potent synthetic ligands are fibrates and thiazolidindiones. Future investigations should now focus on the mechanisms of PPARs activation, which might present new approaches involved in the antiatherosclerotic effects revealed in this review. In addition, in this review we are presenting latest data from recent performed clinical studies which have focus on novel approach to PPARs agonists as potential therapeutic agents in the treatment of complex disease such as atherosclerosis.",
journal = "Angiology",
title = "Peroxisome Proliferator-Activated Receptors and Atherosclerosis",
volume = "62",
number = "7",
pages = "523-534",
doi = "10.1177/0003319711401012"
}
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Extended Time of Cold Ischemia and Its Influence on the Physiological Function of Human Adult Pancreatic Islets

Nikolić, Dragana; Djordjevic, P. B.; Radak, Đorđe J.; Lackovic, Vesna B.; Bajčetić, Miloš I.; Milic, Gordana; Gostiljac, D.; Ilic, M.; Raketic, Nevenka; Stojiljković, Vesna; Grubor, Nikica M.; Jovanovic, M. D.; Latincic, S. M.

(2011)

TY  - JOUR
AU  - Nikolić, Dragana
AU  - Djordjevic, P. B.
AU  - Radak, Đorđe J.
AU  - Lackovic, Vesna B.
AU  - Bajčetić, Miloš I.
AU  - Milic, Gordana
AU  - Gostiljac, D.
AU  - Ilic, M.
AU  - Raketic, Nevenka
AU  - Stojiljković, Vesna
AU  - Grubor, Nikica M.
AU  - Jovanovic, M. D.
AU  - Latincic, S. M.
PY  - 2011
UR  - http://vinar.vin.bg.ac.rs/handle/123456789/4653
AB  - In this study we compared the effects of duration of cold ischemia (longer and shorter ischemia) on the yield, viability and preservation of the physiological function and insulin secretion of adult human pancreatic islets in short-term (seven days) culture. Based on the tested parameters, we established that there are no major differences between these two test groups and that the storage and transport of pancreatic tissue in physiological solution at 4 degrees C gives quite satisfactory results.
T2  - Archives of biological sciences
T1  - Extended Time of Cold Ischemia and Its Influence on the Physiological Function of Human Adult Pancreatic Islets
VL  - 63
IS  - 4
SP  - 1007
EP  - 1013
DO  - 10.2298/ABS1104007N
ER  - 
@article{
author = "Nikolić, Dragana and Djordjevic, P. B. and Radak, Đorđe J. and Lackovic, Vesna B. and Bajčetić, Miloš I. and Milic, Gordana and Gostiljac, D. and Ilic, M. and Raketic, Nevenka and Stojiljković, Vesna and Grubor, Nikica M. and Jovanovic, M. D. and Latincic, S. M.",
year = "2011",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/4653",
abstract = "In this study we compared the effects of duration of cold ischemia (longer and shorter ischemia) on the yield, viability and preservation of the physiological function and insulin secretion of adult human pancreatic islets in short-term (seven days) culture. Based on the tested parameters, we established that there are no major differences between these two test groups and that the storage and transport of pancreatic tissue in physiological solution at 4 degrees C gives quite satisfactory results.",
journal = "Archives of biological sciences",
title = "Extended Time of Cold Ischemia and Its Influence on the Physiological Function of Human Adult Pancreatic Islets",
volume = "63",
number = "4",
pages = "1007-1013",
doi = "10.2298/ABS1104007N"
}

Involvement of the ADAM 12 in Thrombin-Induced Rats VSMCs Proliferation

Smiljanić, Katarina; Dobutovic, B.; Obradović, Milan M.; Nikolić, Dragana; Marche, Pierre; Isenović, Esma R.

(2011)

@article{
author = "Smiljanić, Katarina and Dobutovic, B. and Obradović, Milan M. and Nikolić, Dragana and Marche, Pierre and Isenović, Esma R.",
year = "2011",
url = "http://vinar.vin.bg.ac.rs/handle/123456789/4468",
abstract = "Cardiovascular disease is the largest single cause of mortality and its major underlying pathology is atherosclerosis. The proliferation of vascular smooth muscle cells (VSMCs) is a key event in the pathogenesis of the various vascular diseases, including atherosclerosis and hypertension. Thrombin (Thr) is involved in the abnormal proliferation of VSMCs associated with atherosclerosis and hypertension. ADAMs (A Disintegrin And Metalloproteinase) are transmembrane metalloproteinases, belonging to the adamalysins group, that are distinct from matrix metalloproteinases (MMPs) in a way as they have an extracellular disintegrin domain and cytoplasmic domain that can associate with intracellular proteins. There is limited knowledge about the presence of ADAM metalloproteinase activity in Thr-induced VSMCs proliferation. Therefore, this review examines recent findings in signaling mechanisms employed by Thr in modulating the regulation of proliferation of VSMCs with particular emphasis on involvement of ADAM 12 which has been identified as an important mediator of VSMCs hypertrophy and vascular diseases. These findings are critical for understanding the role of Thr in vascular biology and vascular diseases.",
journal = "Current Medicinal Chemistry",
title = "Involvement of the ADAM 12 in Thrombin-Induced Rats VSMCs Proliferation",
volume = "18",
number = "22",
pages = "3382-3386",
doi = "10.2174/092986711796504709"
}
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