TY  - CONF
AU  - Adžić, Miroslav
AU  - Đorđević, A.
AU  - Đorđević, Jelena
AU  - Krstić-Demonacos, Marija
AU  - Radojčić, Marija
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9377
AB  - Glucocorticoids have diverse effects in cellular processes in hippocampus (HIPPO) under stress. Beside genomic pathways, their effects are also mediated by direct activation of subfamily of mitogen-activated protein kinases termed, c-Jun-Nterminal kinases (JNKs). We analysed the phosphorylation status of cytoplasmic and nuclear JNK isoforms, and expression of its inhibitor Hsp70 protein in HIPPO of rats exposed to diverse types of stress. Activity of JNK1 in cytoplasm and nucleus was decreased in all types of stress, while the activity of cytoplasmic JNK2/3 was markedly higher in acute stress, and unaltered or lowered in chronic and combined stress. Hsp70 was significantly decreased in cytoplasm and increased in nucleus under all stress conditions indicating its cytoplasmic-nuclear translocation.
PB  - Society of Physical Chemists of Serbia
C3  - Physical chemistry 2008 : 9th international conference on fundamental and applied aspects of physical chemistry
T1  - Stress effects on the phosphorylation of c-jun-nterminal kinases and on nuclear translocation of hsp70 in rat hippocampus
VL  - 1
SP  - 438
EP  - 440
UR  - https://hdl.handle.net/21.15107/rcub_vinar_9377
ER  - 

@conference{
author = "Adžić, Miroslav and Đorđević, A. and Đorđević, Jelena and Krstić-Demonacos, Marija and Radojčić, Marija",
year = "2008",
abstract = "Glucocorticoids have diverse effects in cellular processes in hippocampus (HIPPO) under stress. Beside genomic pathways, their effects are also mediated by direct activation of subfamily of mitogen-activated protein kinases termed, c-Jun-Nterminal kinases (JNKs). We analysed the phosphorylation status of cytoplasmic and nuclear JNK isoforms, and expression of its inhibitor Hsp70 protein in HIPPO of rats exposed to diverse types of stress. Activity of JNK1 in cytoplasm and nucleus was decreased in all types of stress, while the activity of cytoplasmic JNK2/3 was markedly higher in acute stress, and unaltered or lowered in chronic and combined stress. Hsp70 was significantly decreased in cytoplasm and increased in nucleus under all stress conditions indicating its cytoplasmic-nuclear translocation.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2008 : 9th international conference on fundamental and applied aspects of physical chemistry",
title = "Stress effects on the phosphorylation of c-jun-nterminal kinases and on nuclear translocation of hsp70 in rat hippocampus",
volume = "1",
pages = "438-440",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9377"
}

Adžić, M., Đorđević, A., Đorđević, J., Krstić-Demonacos, M.,& Radojčić, M.. (2008). Stress effects on the phosphorylation of c-jun-nterminal kinases and on nuclear translocation of hsp70 in rat hippocampus. in Physical chemistry 2008 : 9th international conference on fundamental and applied aspects of physical chemistry
Society of Physical Chemists of Serbia., 1, 438-440.
https://hdl.handle.net/21.15107/rcub_vinar_9377

Adžić M, Đorđević A, Đorđević J, Krstić-Demonacos M, Radojčić M. Stress effects on the phosphorylation of c-jun-nterminal kinases and on nuclear translocation of hsp70 in rat hippocampus. in Physical chemistry 2008 : 9th international conference on fundamental and applied aspects of physical chemistry. 2008;1:438-440.
https://hdl.handle.net/21.15107/rcub_vinar_9377 .

Adžić, Miroslav, Đorđević, A., Đorđević, Jelena, Krstić-Demonacos, Marija, Radojčić, Marija, "Stress effects on the phosphorylation of c-jun-nterminal kinases and on nuclear translocation of hsp70 in rat hippocampus" in Physical chemistry 2008 : 9th international conference on fundamental and applied aspects of physical chemistry, 1 (2008):438-440,
https://hdl.handle.net/21.15107/rcub_vinar_9377 .