TY  - JOUR
AU  - Obradović, Milica
AU  - Gluvić, Zoran
AU  - Petrović, Nina
AU  - Obradović, Milan M.
AU  - Tomasevic, Ratko
AU  - Dugalic, Predrag
AU  - Isenović, Esma R.
PY  - 2017
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/1700
AB  - Introduction. Chronic liver diseases (CLD) are an important cause of morbidity and mortality in general population. The aim of this study was to analyze potential differences between patients with CLD and healthy control group, and to estimate the severity of CLD by using simple questionnaires: general health questionnaire (GHQ-12) and chronic liver disease questionnaire (CLDQ). Methods. A cross-sectional pilot study was performed in Zemun Clinical Hospital during years 2014 and 2015. Sixty participants were divided into 4 groups (15 per group): chronic alcoholic hepatitis, other chronic hepatitis, liver cirrhosis, and healthy control group. Entire study population chose one of four offered answers of structured questionnaires GHQ-12 and CLDQ, based on which mean model of end-stage liver disease (MELD) and Child-Turcotte-Pugh (CTP) scores were calculated. Results. Mean GHQ12 and CLDQ scores were 10.5 and 5.21 +/- 1.11 respectively. Regarding certain CLDQ domain scores, a significant difference between alcoholic and non-alcoholic hepatitis groups in the worry domain was observed. Mean MELD score was 7.42 +/- 2.89 and did not differ between chronic hepatitis groups, while mean CTP score was 5.73 +/- 0.88. A statistically significant correlation was observed between GHQ12 and CLDQ scores (rho = -0.404, p LT 0.01), but not between subjective and objective scores. Conclusions. Mean GHQ12 and CLDQ scores pointed out to general psychological no-distress condition of the studied participants, as well as scarcely expressed CLD-specific complaints. Mean MELD and CTP scores indicated stable chronic liver diseases, with low three-month mortality rates in the cases of chronic hepatitis, as well as determination to Child A group in the case of liver cirrhosis.
T2  - Romanian Journal of Internal Medicine
T1  - A quality of life assessment and the correlation between generic and disease-specific questionnaires scores in outpatients with chronic liver disease-pilot study
VL  - 55
IS  - 3
SP  - 129
EP  - 137
DO  - 10.1515/rjim-2017-0014
ER  - 

@article{
author = "Obradović, Milica and Gluvić, Zoran and Petrović, Nina and Obradović, Milan M. and Tomasevic, Ratko and Dugalic, Predrag and Isenović, Esma R.",
year = "2017",
abstract = "Introduction. Chronic liver diseases (CLD) are an important cause of morbidity and mortality in general population. The aim of this study was to analyze potential differences between patients with CLD and healthy control group, and to estimate the severity of CLD by using simple questionnaires: general health questionnaire (GHQ-12) and chronic liver disease questionnaire (CLDQ). Methods. A cross-sectional pilot study was performed in Zemun Clinical Hospital during years 2014 and 2015. Sixty participants were divided into 4 groups (15 per group): chronic alcoholic hepatitis, other chronic hepatitis, liver cirrhosis, and healthy control group. Entire study population chose one of four offered answers of structured questionnaires GHQ-12 and CLDQ, based on which mean model of end-stage liver disease (MELD) and Child-Turcotte-Pugh (CTP) scores were calculated. Results. Mean GHQ12 and CLDQ scores were 10.5 and 5.21 +/- 1.11 respectively. Regarding certain CLDQ domain scores, a significant difference between alcoholic and non-alcoholic hepatitis groups in the worry domain was observed. Mean MELD score was 7.42 +/- 2.89 and did not differ between chronic hepatitis groups, while mean CTP score was 5.73 +/- 0.88. A statistically significant correlation was observed between GHQ12 and CLDQ scores (rho = -0.404, p LT 0.01), but not between subjective and objective scores. Conclusions. Mean GHQ12 and CLDQ scores pointed out to general psychological no-distress condition of the studied participants, as well as scarcely expressed CLD-specific complaints. Mean MELD and CTP scores indicated stable chronic liver diseases, with low three-month mortality rates in the cases of chronic hepatitis, as well as determination to Child A group in the case of liver cirrhosis.",
journal = "Romanian Journal of Internal Medicine",
title = "A quality of life assessment and the correlation between generic and disease-specific questionnaires scores in outpatients with chronic liver disease-pilot study",
volume = "55",
number = "3",
pages = "129-137",
doi = "10.1515/rjim-2017-0014"
}

Obradović, M., Gluvić, Z., Petrović, N., Obradović, M. M., Tomasevic, R., Dugalic, P.,& Isenović, E. R.. (2017). A quality of life assessment and the correlation between generic and disease-specific questionnaires scores in outpatients with chronic liver disease-pilot study. in Romanian Journal of Internal Medicine, 55(3), 129-137.
https://doi.org/10.1515/rjim-2017-0014

Obradović M, Gluvić Z, Petrović N, Obradović MM, Tomasevic R, Dugalic P, Isenović ER. A quality of life assessment and the correlation between generic and disease-specific questionnaires scores in outpatients with chronic liver disease-pilot study. in Romanian Journal of Internal Medicine. 2017;55(3):129-137.
doi:10.1515/rjim-2017-0014 .

Obradović, Milica, Gluvić, Zoran, Petrović, Nina, Obradović, Milan M., Tomasevic, Ratko, Dugalic, Predrag, Isenović, Esma R., "A quality of life assessment and the correlation between generic and disease-specific questionnaires scores in outpatients with chronic liver disease-pilot study" in Romanian Journal of Internal Medicine, 55, no. 3 (2017):129-137,
https://doi.org/10.1515/rjim-2017-0014 . .

TY  - JOUR
AU  - Gluvić, Zoran
AU  - Sudar, Emina
AU  - Tica, Jelena
AU  - Jovanović, Aleksandra
AU  - Zafirović, Sonja
AU  - Tomasevic, Ratko
AU  - Isenović, Esma R.
PY  - 2015
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/459
AB  - The aim of this study was to investigate the effect of levothyroxine (LT4) replacement therapy during three months on some parameters of metabolic syndrome and atherosclerosis in patients with increased thyroid-stimulating hormone (TSH) level. This study included a group of 30 female patients with TSH level GT 4mIU/L and 15 matched healthy controls. Intima media complex thickness (IMCT) and peak systolic flow velocity (PSFV) of superficial femoral artery were determined by Color Doppler scan. In hypothyroid subjects, BMI, SBP, DBP, and TSH were significantly increased versus controls and decreased after LT4 administration. FT4 was significantly lower in hypothyroid subjects compared with controls and significantly higher by treatment. TC, Tg, HDLC, and LDL-C were similar to controls at baseline but TC and LDL-C were significantly decreased by LH4 treatment. IMCT was significantly increased versus controls at baseline and significantly reduced by treatment. PSFV was similar to controls at baseline and significantly decreased on treatment. In this study, we have demonstrated the effects of LT4 replacement therapy during three months of treatment on correction of risk factors of metabolic syndrome and atherosclerosis.
T2  - International Journal of Endocrinology
T1  - Effects of Levothyroxine Replacement Therapy on Parameters of Metabolic Syndrome and Atherosclerosis in Hypothyroid Patients: A Prospective Pilot Study
DO  - 10.1155/2015/147070
ER  - 

@article{
author = "Gluvić, Zoran and Sudar, Emina and Tica, Jelena and Jovanović, Aleksandra and Zafirović, Sonja and Tomasevic, Ratko and Isenović, Esma R.",
year = "2015",
abstract = "The aim of this study was to investigate the effect of levothyroxine (LT4) replacement therapy during three months on some parameters of metabolic syndrome and atherosclerosis in patients with increased thyroid-stimulating hormone (TSH) level. This study included a group of 30 female patients with TSH level GT 4mIU/L and 15 matched healthy controls. Intima media complex thickness (IMCT) and peak systolic flow velocity (PSFV) of superficial femoral artery were determined by Color Doppler scan. In hypothyroid subjects, BMI, SBP, DBP, and TSH were significantly increased versus controls and decreased after LT4 administration. FT4 was significantly lower in hypothyroid subjects compared with controls and significantly higher by treatment. TC, Tg, HDLC, and LDL-C were similar to controls at baseline but TC and LDL-C were significantly decreased by LH4 treatment. IMCT was significantly increased versus controls at baseline and significantly reduced by treatment. PSFV was similar to controls at baseline and significantly decreased on treatment. In this study, we have demonstrated the effects of LT4 replacement therapy during three months of treatment on correction of risk factors of metabolic syndrome and atherosclerosis.",
journal = "International Journal of Endocrinology",
title = "Effects of Levothyroxine Replacement Therapy on Parameters of Metabolic Syndrome and Atherosclerosis in Hypothyroid Patients: A Prospective Pilot Study",
doi = "10.1155/2015/147070"
}

Gluvić, Z., Sudar, E., Tica, J., Jovanović, A., Zafirović, S., Tomasevic, R.,& Isenović, E. R.. (2015). Effects of Levothyroxine Replacement Therapy on Parameters of Metabolic Syndrome and Atherosclerosis in Hypothyroid Patients: A Prospective Pilot Study. in International Journal of Endocrinology.
https://doi.org/10.1155/2015/147070

Gluvić Z, Sudar E, Tica J, Jovanović A, Zafirović S, Tomasevic R, Isenović ER. Effects of Levothyroxine Replacement Therapy on Parameters of Metabolic Syndrome and Atherosclerosis in Hypothyroid Patients: A Prospective Pilot Study. in International Journal of Endocrinology. 2015;.
doi:10.1155/2015/147070 .

Gluvić, Zoran, Sudar, Emina, Tica, Jelena, Jovanović, Aleksandra, Zafirović, Sonja, Tomasevic, Ratko, Isenović, Esma R., "Effects of Levothyroxine Replacement Therapy on Parameters of Metabolic Syndrome and Atherosclerosis in Hypothyroid Patients: A Prospective Pilot Study" in International Journal of Endocrinology (2015),
https://doi.org/10.1155/2015/147070 . .

TY  - JOUR
AU  - Gluvić, Zoran
AU  - Slovic, Miodrag
AU  - Dugalic, Predrag
AU  - Tomasevic, Ratko
AU  - Pavlović, Aleksandar
AU  - Jaksic, Dunja
AU  - Isenović, Esma R.
AU  - Rasic-Milutinovic, Zorica
AU  - Milicevic, Dusan
PY  - 2008
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/3514
AB  - Objective This study examined the sensitivity of routine abdominal ultrasound scanning in the detection of colonic malignancy. Patients and Methods A case control prospective study included 101 patients hospitalized at the Department of Gastroenterology and Liver Diseases of Zemun Clinical Hospital over a four-year period. Since the complaints pointed to colonic malignancy, the patients underwent routine golden standard diagnostic procedures. These patients were referred to an experienced abdominal ultrasound operator who searched for some characteristic signs of colonic malignancy. All of the participants were surgically treated after the completion of relevant procedures for diagnosing colonic malignancy. SPSS for Windows 10.0 was used for data analysis. Results The sensitivity of an abdominal ultrasound scan in the detection and location of pathological changes pointed to colonic malignancy was different- 76% and 84% respectively. This method was very reliable in detecting right-sided colonic carcinoma (100%). Some specific ultrasonographic signs of colonic carcinoma were observed at the advanced stages of disease. Conclusions The routine abdominal ultrasonography can be used for the screening of colonic malignancy owing to its high sensitivity, particularly in advanced disease, but solely in conjunction with other methods. Finally, abdominal ultrasonography cannot be a definitive diagnostic tool for colonic carcinoma.
T2  - Internal Medicine, Tokyo
T1  - Is the routine abdominal ultrasound a sufficiently sensitive method for the detection of colonic malignancy?
VL  - 47
IS  - 9
SP  - 827
EP  - 831
DO  - 10.2169/internalmedicine.47.0695
ER  - 

@article{
author = "Gluvić, Zoran and Slovic, Miodrag and Dugalic, Predrag and Tomasevic, Ratko and Pavlović, Aleksandar and Jaksic, Dunja and Isenović, Esma R. and Rasic-Milutinovic, Zorica and Milicevic, Dusan",
year = "2008",
abstract = "Objective This study examined the sensitivity of routine abdominal ultrasound scanning in the detection of colonic malignancy. Patients and Methods A case control prospective study included 101 patients hospitalized at the Department of Gastroenterology and Liver Diseases of Zemun Clinical Hospital over a four-year period. Since the complaints pointed to colonic malignancy, the patients underwent routine golden standard diagnostic procedures. These patients were referred to an experienced abdominal ultrasound operator who searched for some characteristic signs of colonic malignancy. All of the participants were surgically treated after the completion of relevant procedures for diagnosing colonic malignancy. SPSS for Windows 10.0 was used for data analysis. Results The sensitivity of an abdominal ultrasound scan in the detection and location of pathological changes pointed to colonic malignancy was different- 76% and 84% respectively. This method was very reliable in detecting right-sided colonic carcinoma (100%). Some specific ultrasonographic signs of colonic carcinoma were observed at the advanced stages of disease. Conclusions The routine abdominal ultrasonography can be used for the screening of colonic malignancy owing to its high sensitivity, particularly in advanced disease, but solely in conjunction with other methods. Finally, abdominal ultrasonography cannot be a definitive diagnostic tool for colonic carcinoma.",
journal = "Internal Medicine, Tokyo",
title = "Is the routine abdominal ultrasound a sufficiently sensitive method for the detection of colonic malignancy?",
volume = "47",
number = "9",
pages = "827-831",
doi = "10.2169/internalmedicine.47.0695"
}

Gluvić, Z., Slovic, M., Dugalic, P., Tomasevic, R., Pavlović, A., Jaksic, D., Isenović, E. R., Rasic-Milutinovic, Z.,& Milicevic, D.. (2008). Is the routine abdominal ultrasound a sufficiently sensitive method for the detection of colonic malignancy?. in Internal Medicine, Tokyo, 47(9), 827-831.
https://doi.org/10.2169/internalmedicine.47.0695

Gluvić Z, Slovic M, Dugalic P, Tomasevic R, Pavlović A, Jaksic D, Isenović ER, Rasic-Milutinovic Z, Milicevic D. Is the routine abdominal ultrasound a sufficiently sensitive method for the detection of colonic malignancy?. in Internal Medicine, Tokyo. 2008;47(9):827-831.
doi:10.2169/internalmedicine.47.0695 .

Gluvić, Zoran, Slovic, Miodrag, Dugalic, Predrag, Tomasevic, Ratko, Pavlović, Aleksandar, Jaksic, Dunja, Isenović, Esma R., Rasic-Milutinovic, Zorica, Milicevic, Dusan, "Is the routine abdominal ultrasound a sufficiently sensitive method for the detection of colonic malignancy?" in Internal Medicine, Tokyo, 47, no. 9 (2008):827-831,
https://doi.org/10.2169/internalmedicine.47.0695 . .