TY  - JOUR
AU  - Bajić, Vladan P.
AU  - Spremo-Potparević, Biljana
AU  - Živković, Lada
AU  - Isenović, Esma R.
AU  - Arendt, Thomas
PY  - 2015
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/664
AB  - Neurons are postmitotic cells that are in permanent cell cycle arrest. However, components of the cell cycle machinery that are expressed in Alzheimers disease (AD) neurons are showing features of a cycling cell and those attributed to a postmitotic cell as well. Furthermore, the unique physiological operations taking place in neurons, ascribed to core cell cycle regulators are also key regulators in cell division. Functions of these cell cycle regulators include neuronal migration, axonal elongation, axon pruning, dendrite morphogenesis and synaptic maturation and plasticity. In this review, we focus on cohesion and cohesion related proteins in reference to their neuronal functions and how impaired centromere/cohesion dynamics may connect cell cycle dysfunction to aneuploidy in AD. (C) 2015 Elsevier Ltd. All rights reserved.
T2  - Neuroscience and Biobehavioral Reviews
T1  - Cohesion and the aneuploid phenotype in Alzheimers disease: A tale of genome instability
VL  - 55
SP  - 365
EP  - 374
DO  - 10.1016/j.neubiorev.2015.05.010
ER  - 

@article{
author = "Bajić, Vladan P. and Spremo-Potparević, Biljana and Živković, Lada and Isenović, Esma R. and Arendt, Thomas",
year = "2015",
abstract = "Neurons are postmitotic cells that are in permanent cell cycle arrest. However, components of the cell cycle machinery that are expressed in Alzheimers disease (AD) neurons are showing features of a cycling cell and those attributed to a postmitotic cell as well. Furthermore, the unique physiological operations taking place in neurons, ascribed to core cell cycle regulators are also key regulators in cell division. Functions of these cell cycle regulators include neuronal migration, axonal elongation, axon pruning, dendrite morphogenesis and synaptic maturation and plasticity. In this review, we focus on cohesion and cohesion related proteins in reference to their neuronal functions and how impaired centromere/cohesion dynamics may connect cell cycle dysfunction to aneuploidy in AD. (C) 2015 Elsevier Ltd. All rights reserved.",
journal = "Neuroscience and Biobehavioral Reviews",
title = "Cohesion and the aneuploid phenotype in Alzheimers disease: A tale of genome instability",
volume = "55",
pages = "365-374",
doi = "10.1016/j.neubiorev.2015.05.010"
}

Bajić, V. P., Spremo-Potparević, B., Živković, L., Isenović, E. R.,& Arendt, T.. (2015). Cohesion and the aneuploid phenotype in Alzheimers disease: A tale of genome instability. in Neuroscience and Biobehavioral Reviews, 55, 365-374.
https://doi.org/10.1016/j.neubiorev.2015.05.010

Bajić VP, Spremo-Potparević B, Živković L, Isenović ER, Arendt T. Cohesion and the aneuploid phenotype in Alzheimers disease: A tale of genome instability. in Neuroscience and Biobehavioral Reviews. 2015;55:365-374.
doi:10.1016/j.neubiorev.2015.05.010 .

Bajić, Vladan P., Spremo-Potparević, Biljana, Živković, Lada, Isenović, Esma R., Arendt, Thomas, "Cohesion and the aneuploid phenotype in Alzheimers disease: A tale of genome instability" in Neuroscience and Biobehavioral Reviews, 55 (2015):365-374,
https://doi.org/10.1016/j.neubiorev.2015.05.010 . .