Size of silver nanoparticles determines proliferation ability of human circulating lymphocytes in vitro
Само за регистроване кориснике
2016
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
In this work we present biological effects of silver nanoparticles (AgNPs) synthesized by picosecond laser ablation of silver in deionized water. We examined induction of chromosomal aberrations, lymphocyte micronuclei, appearance and recovery of double strand breaks (DSBs) of DNA, cell proliferation potential, concentration of lipid peroxidation products and insulin-like growth factor 1 (ILGF-1). We found that AgNPs sized from 3 nm to 8 nm induce cell cytostasis, which is accompanied with its clastogenic action on DNA, while AgNPs, sized 2 nm behaves contrary stimulating cell proliferation by enhancing ILGF-1 concentration. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
Кључне речи:
AgNPs / Size / DNA damages / Cell stasis / Human primary cellsИзвор:
Toxicology Letters, 2016, 247, 29-34Издавач:
- Elsevier
Финансирање / пројекти:
- Ефекти дејства ласерског зрачења и плазме на савремене материјале при њиховој синтези, модификацији и анализи (RS-MESTD-Basic Research (BR or ON)-172019)
- Радиосензитивност хуманог генома (RS-MESTD-Basic Research (BR or ON)-173046)
DOI: 10.1016/j.toxlet.2016.02.007
ISSN: 0378-4274; 1879-3169
PubMed: 26892717
WoS: 000372432600003
Scopus: 2-s2.0-84958554631
Колекције
Институција/група
VinčaTY - JOUR AU - Joksić, Gordana AU - Stašić, Jelena AU - Filipović, Jelena G. AU - Valenta-Šobot, Ana AU - Trtica, Milan PY - 2016 UR - https://vinar.vin.bg.ac.rs/handle/123456789/976 AB - In this work we present biological effects of silver nanoparticles (AgNPs) synthesized by picosecond laser ablation of silver in deionized water. We examined induction of chromosomal aberrations, lymphocyte micronuclei, appearance and recovery of double strand breaks (DSBs) of DNA, cell proliferation potential, concentration of lipid peroxidation products and insulin-like growth factor 1 (ILGF-1). We found that AgNPs sized from 3 nm to 8 nm induce cell cytostasis, which is accompanied with its clastogenic action on DNA, while AgNPs, sized 2 nm behaves contrary stimulating cell proliferation by enhancing ILGF-1 concentration. (C) 2016 Elsevier Ireland Ltd. All rights reserved. PB - Elsevier T2 - Toxicology Letters T1 - Size of silver nanoparticles determines proliferation ability of human circulating lymphocytes in vitro VL - 247 SP - 29 EP - 34 DO - 10.1016/j.toxlet.2016.02.007 ER -
@article{ author = "Joksić, Gordana and Stašić, Jelena and Filipović, Jelena G. and Valenta-Šobot, Ana and Trtica, Milan", year = "2016", abstract = "In this work we present biological effects of silver nanoparticles (AgNPs) synthesized by picosecond laser ablation of silver in deionized water. We examined induction of chromosomal aberrations, lymphocyte micronuclei, appearance and recovery of double strand breaks (DSBs) of DNA, cell proliferation potential, concentration of lipid peroxidation products and insulin-like growth factor 1 (ILGF-1). We found that AgNPs sized from 3 nm to 8 nm induce cell cytostasis, which is accompanied with its clastogenic action on DNA, while AgNPs, sized 2 nm behaves contrary stimulating cell proliferation by enhancing ILGF-1 concentration. (C) 2016 Elsevier Ireland Ltd. All rights reserved.", publisher = "Elsevier", journal = "Toxicology Letters", title = "Size of silver nanoparticles determines proliferation ability of human circulating lymphocytes in vitro", volume = "247", pages = "29-34", doi = "10.1016/j.toxlet.2016.02.007" }
Joksić, G., Stašić, J., Filipović, J. G., Valenta-Šobot, A.,& Trtica, M.. (2016). Size of silver nanoparticles determines proliferation ability of human circulating lymphocytes in vitro. in Toxicology Letters Elsevier., 247, 29-34. https://doi.org/10.1016/j.toxlet.2016.02.007
Joksić G, Stašić J, Filipović JG, Valenta-Šobot A, Trtica M. Size of silver nanoparticles determines proliferation ability of human circulating lymphocytes in vitro. in Toxicology Letters. 2016;247:29-34. doi:10.1016/j.toxlet.2016.02.007 .
Joksić, Gordana, Stašić, Jelena, Filipović, Jelena G., Valenta-Šobot, Ana, Trtica, Milan, "Size of silver nanoparticles determines proliferation ability of human circulating lymphocytes in vitro" in Toxicology Letters, 247 (2016):29-34, https://doi.org/10.1016/j.toxlet.2016.02.007 . .