Suitability of TiO2 nanoparticles and prolate nanospheroids for laser desorption/ionization mass spectrometric characterization of bipyridine-containing complexes
Само за регистроване кориснике
2015
Аутори
Popović, Iva A.Nešić, Maja D.
Nišavić, Marija
Vranješ, Mila
Radetić, Tamara
Šaponjić, Zoran
Masnikosa, Romana
Petković, Marijana
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Nanostructured materials as substrates for surface-assisted laser desorption and ionization time-of-flight mass spectrometry have two main advantages such as small number of signals in the low mass range and salt tolerance. We have also previously observed decreased extent of undesired fragmentation of bipyridine-containing transition metal complexes in the presence of TiO2 nanoparticles (NPs). In this work, we extended our previous study and tested whether both TiO2 NPs and TiO2 prolate nanospheroids (PNSs) can be used as substrates for SALDI-MS of bipyridine-containing transition metal complexes and whether they tolerate intense laser and the presence of inorganic salts. TiO2 NPs (an average diameter of 5 nm) and PNSs (length: 40-50 nm, the lateral dimension: 14-16 nm) were characterized microscopically and their mass spectra were analyzed, as well as the spectra of bipyridine-containing Pt(II) and Ru(III) complexes. Our results show that seven times higher analyte signals can be obt...ained in the presence of PNSs compared to the signals acquired with NPs and three times higher compared to spectra acquired without a substrate. The presence of inorganic salt did not affect the spectra, which makes both TiO2 nanocrystals suitable for MS analysis of transition metal complexes in biological fluids. (C) 2015 Elsevier B.V. All rights reserved.
Кључне речи:
Titania nanoparticles / Prolate nanospheroids / SALDI-TOF MS / Bipyridine complexes / Salt toleranceИзвор:
Materials Letters, 2015, 150, 84-88Финансирање / пројекти:
- Испитивање механизма реакција комплекса јона прелазних метала са биолошки значајним молекулима (RS-172011)
- Утицај величине, облика и структуре наночестица на њихова својства и својства нанокомпозита (RS-172056)
- bilateral German-Serbian project - German Academic Exchange Office (Deutscher Akademischer Austauschdienst, DAAD)
DOI: 10.1016/j.matlet.2015.03.004
ISSN: 0167-577X; 1873-4979
WoS: 000354580400023
Scopus: 2-s2.0-84925125581
Колекције
Институција/група
VinčaTY - JOUR AU - Popović, Iva A. AU - Nešić, Maja D. AU - Nišavić, Marija AU - Vranješ, Mila AU - Radetić, Tamara AU - Šaponjić, Zoran AU - Masnikosa, Romana AU - Petković, Marijana PY - 2015 UR - https://vinar.vin.bg.ac.rs/handle/123456789/544 AB - Nanostructured materials as substrates for surface-assisted laser desorption and ionization time-of-flight mass spectrometry have two main advantages such as small number of signals in the low mass range and salt tolerance. We have also previously observed decreased extent of undesired fragmentation of bipyridine-containing transition metal complexes in the presence of TiO2 nanoparticles (NPs). In this work, we extended our previous study and tested whether both TiO2 NPs and TiO2 prolate nanospheroids (PNSs) can be used as substrates for SALDI-MS of bipyridine-containing transition metal complexes and whether they tolerate intense laser and the presence of inorganic salts. TiO2 NPs (an average diameter of 5 nm) and PNSs (length: 40-50 nm, the lateral dimension: 14-16 nm) were characterized microscopically and their mass spectra were analyzed, as well as the spectra of bipyridine-containing Pt(II) and Ru(III) complexes. Our results show that seven times higher analyte signals can be obtained in the presence of PNSs compared to the signals acquired with NPs and three times higher compared to spectra acquired without a substrate. The presence of inorganic salt did not affect the spectra, which makes both TiO2 nanocrystals suitable for MS analysis of transition metal complexes in biological fluids. (C) 2015 Elsevier B.V. All rights reserved. T2 - Materials Letters T1 - Suitability of TiO2 nanoparticles and prolate nanospheroids for laser desorption/ionization mass spectrometric characterization of bipyridine-containing complexes VL - 150 SP - 84 EP - 88 DO - 10.1016/j.matlet.2015.03.004 ER -
@article{ author = "Popović, Iva A. and Nešić, Maja D. and Nišavić, Marija and Vranješ, Mila and Radetić, Tamara and Šaponjić, Zoran and Masnikosa, Romana and Petković, Marijana", year = "2015", abstract = "Nanostructured materials as substrates for surface-assisted laser desorption and ionization time-of-flight mass spectrometry have two main advantages such as small number of signals in the low mass range and salt tolerance. We have also previously observed decreased extent of undesired fragmentation of bipyridine-containing transition metal complexes in the presence of TiO2 nanoparticles (NPs). In this work, we extended our previous study and tested whether both TiO2 NPs and TiO2 prolate nanospheroids (PNSs) can be used as substrates for SALDI-MS of bipyridine-containing transition metal complexes and whether they tolerate intense laser and the presence of inorganic salts. TiO2 NPs (an average diameter of 5 nm) and PNSs (length: 40-50 nm, the lateral dimension: 14-16 nm) were characterized microscopically and their mass spectra were analyzed, as well as the spectra of bipyridine-containing Pt(II) and Ru(III) complexes. Our results show that seven times higher analyte signals can be obtained in the presence of PNSs compared to the signals acquired with NPs and three times higher compared to spectra acquired without a substrate. The presence of inorganic salt did not affect the spectra, which makes both TiO2 nanocrystals suitable for MS analysis of transition metal complexes in biological fluids. (C) 2015 Elsevier B.V. All rights reserved.", journal = "Materials Letters", title = "Suitability of TiO2 nanoparticles and prolate nanospheroids for laser desorption/ionization mass spectrometric characterization of bipyridine-containing complexes", volume = "150", pages = "84-88", doi = "10.1016/j.matlet.2015.03.004" }
Popović, I. A., Nešić, M. D., Nišavić, M., Vranješ, M., Radetić, T., Šaponjić, Z., Masnikosa, R.,& Petković, M.. (2015). Suitability of TiO2 nanoparticles and prolate nanospheroids for laser desorption/ionization mass spectrometric characterization of bipyridine-containing complexes. in Materials Letters, 150, 84-88. https://doi.org/10.1016/j.matlet.2015.03.004
Popović IA, Nešić MD, Nišavić M, Vranješ M, Radetić T, Šaponjić Z, Masnikosa R, Petković M. Suitability of TiO2 nanoparticles and prolate nanospheroids for laser desorption/ionization mass spectrometric characterization of bipyridine-containing complexes. in Materials Letters. 2015;150:84-88. doi:10.1016/j.matlet.2015.03.004 .
Popović, Iva A., Nešić, Maja D., Nišavić, Marija, Vranješ, Mila, Radetić, Tamara, Šaponjić, Zoran, Masnikosa, Romana, Petković, Marijana, "Suitability of TiO2 nanoparticles and prolate nanospheroids for laser desorption/ionization mass spectrometric characterization of bipyridine-containing complexes" in Materials Letters, 150 (2015):84-88, https://doi.org/10.1016/j.matlet.2015.03.004 . .