Pro12ala Gene Polymorphism in the Peroxisome Proliferator-Activated Receptor Gamma as a Risk Factor for the Onset of Type 2 Diabetes Mellitus in the Serbian Population
Аутори
Soskić, Sanja S.Stanković, Aleksandra
Đurić, Tamara
Živković, Maja
Ristić, P.
Anđelković, Z.
Šumarac-Dumanović, Mirjana
Alavantić, Dragan
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The peroxisome proliferator-activated receptor gamma (PPAR gamma) is a gene candidate for the onset of type 2 diabetes mellitus (T2DM). We investigated the association of the PPAR gamma Pro12Ala gene with the onset of T2DM for the first time in the Serbian population. The study population consisted of 197 controls and 163 T2DM patients. The 12Ala allele tended to be more frequent in the group of T2DM patients (0.11) compared to the control subjects (0.09). The results from this study indicate that the PPAR gamma(2) 12Ala allele presents a non-significant risk factor for T2DM development in the Serbian population.
Кључне речи:
PPAR gamma(2) / Pro12Ala polymorphism / type 2 diabetes mellitus / insulinИзвор:
Archives of Biological Sciences, 2010, 62, 2, 263-270Финансирање / пројекти:
- Serbian Government [M145023]
DOI: 10.2298/ABS1002263S
ISSN: 0354-4664
WoS: 000280017400008
Scopus: 2-s2.0-77955159549
Колекције
Институција/група
VinčaTY - JOUR AU - Soskić, Sanja S. AU - Stanković, Aleksandra AU - Đurić, Tamara AU - Živković, Maja AU - Ristić, P. AU - Anđelković, Z. AU - Šumarac-Dumanović, Mirjana AU - Alavantić, Dragan PY - 2010 UR - https://vinar.vin.bg.ac.rs/handle/123456789/4047 AB - The peroxisome proliferator-activated receptor gamma (PPAR gamma) is a gene candidate for the onset of type 2 diabetes mellitus (T2DM). We investigated the association of the PPAR gamma Pro12Ala gene with the onset of T2DM for the first time in the Serbian population. The study population consisted of 197 controls and 163 T2DM patients. The 12Ala allele tended to be more frequent in the group of T2DM patients (0.11) compared to the control subjects (0.09). The results from this study indicate that the PPAR gamma(2) 12Ala allele presents a non-significant risk factor for T2DM development in the Serbian population. T2 - Archives of Biological Sciences T1 - Pro12ala Gene Polymorphism in the Peroxisome Proliferator-Activated Receptor Gamma as a Risk Factor for the Onset of Type 2 Diabetes Mellitus in the Serbian Population VL - 62 IS - 2 SP - 263 EP - 270 DO - 10.2298/ABS1002263S ER -
@article{ author = "Soskić, Sanja S. and Stanković, Aleksandra and Đurić, Tamara and Živković, Maja and Ristić, P. and Anđelković, Z. and Šumarac-Dumanović, Mirjana and Alavantić, Dragan", year = "2010", abstract = "The peroxisome proliferator-activated receptor gamma (PPAR gamma) is a gene candidate for the onset of type 2 diabetes mellitus (T2DM). We investigated the association of the PPAR gamma Pro12Ala gene with the onset of T2DM for the first time in the Serbian population. The study population consisted of 197 controls and 163 T2DM patients. The 12Ala allele tended to be more frequent in the group of T2DM patients (0.11) compared to the control subjects (0.09). The results from this study indicate that the PPAR gamma(2) 12Ala allele presents a non-significant risk factor for T2DM development in the Serbian population.", journal = "Archives of Biological Sciences", title = "Pro12ala Gene Polymorphism in the Peroxisome Proliferator-Activated Receptor Gamma as a Risk Factor for the Onset of Type 2 Diabetes Mellitus in the Serbian Population", volume = "62", number = "2", pages = "263-270", doi = "10.2298/ABS1002263S" }
Soskić, S. S., Stanković, A., Đurić, T., Živković, M., Ristić, P., Anđelković, Z., Šumarac-Dumanović, M.,& Alavantić, D.. (2010). Pro12ala Gene Polymorphism in the Peroxisome Proliferator-Activated Receptor Gamma as a Risk Factor for the Onset of Type 2 Diabetes Mellitus in the Serbian Population. in Archives of Biological Sciences, 62(2), 263-270. https://doi.org/10.2298/ABS1002263S
Soskić SS, Stanković A, Đurić T, Živković M, Ristić P, Anđelković Z, Šumarac-Dumanović M, Alavantić D. Pro12ala Gene Polymorphism in the Peroxisome Proliferator-Activated Receptor Gamma as a Risk Factor for the Onset of Type 2 Diabetes Mellitus in the Serbian Population. in Archives of Biological Sciences. 2010;62(2):263-270. doi:10.2298/ABS1002263S .
Soskić, Sanja S., Stanković, Aleksandra, Đurić, Tamara, Živković, Maja, Ristić, P., Anđelković, Z., Šumarac-Dumanović, Mirjana, Alavantić, Dragan, "Pro12ala Gene Polymorphism in the Peroxisome Proliferator-Activated Receptor Gamma as a Risk Factor for the Onset of Type 2 Diabetes Mellitus in the Serbian Population" in Archives of Biological Sciences, 62, no. 2 (2010):263-270, https://doi.org/10.2298/ABS1002263S . .