Activity of pituitary-adrenal axis in rats chronically exposed to different stressors
Апстракт
Changes in plasma levels of adrenocorticotropic hormone (ACTH) and corticosterone (COTR) of adult male rats exposed to two chronic types of psychosocial stress: isolation and crowding, as well as physical stress i.e. forced swimming and combined psychosocial and physical stress i.e. isolation accompanied by forced swimming, both under basal conditions and in response to immobilization and cold as short-term stressors, were studied. Chronic isolation produced a significant elevation of basal plasma ACTH and CORT, but chronic isolation accompanied by forced swimming produced a significant elevation only in basal plasma ACTH, but not CORT, while chronic crowding and forced swimming did not elevate the basal plasma levels of these hormones. Chronically stressed animals exposed to immobilization or cold show a significant elevation of plasma CORT No significant differences in plasma CORT between the four chronically stressed groups of rats were recorded. Novel acute immobilization and cold ...stress produce a markedly increased plasma ACTH in chronic crowding, forced swimming and isolation accompanied by forced swimming rats. These data suggest that chronic isolation seems to be a stronger stressor for rats compared to other chronic stressors.
Кључне речи:
ACTH / CORT / chronic physical stress / chronic psychosocial stressИзвор:
Acta Veterinaria, Beograd, 2005, 55, 2-3, 121-129
DOI: 10.2298/AVB0503121D
ISSN: 0567-8315
WoS: 000229817500004
Scopus: 2-s2.0-21344450089
Колекције
Институција/група
VinčaTY - JOUR AU - Dronjak, Slađana AU - Gavrilović, Ljubica PY - 2005 UR - https://vinar.vin.bg.ac.rs/handle/123456789/2900 AB - Changes in plasma levels of adrenocorticotropic hormone (ACTH) and corticosterone (COTR) of adult male rats exposed to two chronic types of psychosocial stress: isolation and crowding, as well as physical stress i.e. forced swimming and combined psychosocial and physical stress i.e. isolation accompanied by forced swimming, both under basal conditions and in response to immobilization and cold as short-term stressors, were studied. Chronic isolation produced a significant elevation of basal plasma ACTH and CORT, but chronic isolation accompanied by forced swimming produced a significant elevation only in basal plasma ACTH, but not CORT, while chronic crowding and forced swimming did not elevate the basal plasma levels of these hormones. Chronically stressed animals exposed to immobilization or cold show a significant elevation of plasma CORT No significant differences in plasma CORT between the four chronically stressed groups of rats were recorded. Novel acute immobilization and cold stress produce a markedly increased plasma ACTH in chronic crowding, forced swimming and isolation accompanied by forced swimming rats. These data suggest that chronic isolation seems to be a stronger stressor for rats compared to other chronic stressors. T2 - Acta Veterinaria, Beograd T1 - Activity of pituitary-adrenal axis in rats chronically exposed to different stressors VL - 55 IS - 2-3 SP - 121 EP - 129 DO - 10.2298/AVB0503121D ER -
@article{ author = "Dronjak, Slađana and Gavrilović, Ljubica", year = "2005", abstract = "Changes in plasma levels of adrenocorticotropic hormone (ACTH) and corticosterone (COTR) of adult male rats exposed to two chronic types of psychosocial stress: isolation and crowding, as well as physical stress i.e. forced swimming and combined psychosocial and physical stress i.e. isolation accompanied by forced swimming, both under basal conditions and in response to immobilization and cold as short-term stressors, were studied. Chronic isolation produced a significant elevation of basal plasma ACTH and CORT, but chronic isolation accompanied by forced swimming produced a significant elevation only in basal plasma ACTH, but not CORT, while chronic crowding and forced swimming did not elevate the basal plasma levels of these hormones. Chronically stressed animals exposed to immobilization or cold show a significant elevation of plasma CORT No significant differences in plasma CORT between the four chronically stressed groups of rats were recorded. Novel acute immobilization and cold stress produce a markedly increased plasma ACTH in chronic crowding, forced swimming and isolation accompanied by forced swimming rats. These data suggest that chronic isolation seems to be a stronger stressor for rats compared to other chronic stressors.", journal = "Acta Veterinaria, Beograd", title = "Activity of pituitary-adrenal axis in rats chronically exposed to different stressors", volume = "55", number = "2-3", pages = "121-129", doi = "10.2298/AVB0503121D" }
Dronjak, S.,& Gavrilović, L.. (2005). Activity of pituitary-adrenal axis in rats chronically exposed to different stressors. in Acta Veterinaria, Beograd, 55(2-3), 121-129. https://doi.org/10.2298/AVB0503121D
Dronjak S, Gavrilović L. Activity of pituitary-adrenal axis in rats chronically exposed to different stressors. in Acta Veterinaria, Beograd. 2005;55(2-3):121-129. doi:10.2298/AVB0503121D .
Dronjak, Slađana, Gavrilović, Ljubica, "Activity of pituitary-adrenal axis in rats chronically exposed to different stressors" in Acta Veterinaria, Beograd, 55, no. 2-3 (2005):121-129, https://doi.org/10.2298/AVB0503121D . .