Genetic variation at the apoB 3 hypervariable region in a Serbian population
Само за регистроване кориснике
1997
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
We investigated common length polymorphism caused by a variable number of tandem repeats in the hypervariable region located at the 3 end of the human apolipoprotein B gene in 696 Serbian (Belgrade area) unrelated individuals of both genders. After using the polymerase chain reaction to amplify this polymorphic region, 17 different alleles, containing 22-54 repeats, were distinguished. The bimodal distribution and the heterozygosity index (average 0.71) obtained in both genders are similar to those reported for other Caucasian populations. However, the HVE34 allele was found to be the commonest in both female and male samples. There was also a lower frequency of the HVE GT 36 alleles than in other Caucasian populations studied.
Кључне речи:
VNTR / apoB / 3 HVR / PCRИзвор:
European Journal of Human Genetics, 1997, 5, 5, 333-335
DOI: 10.1159/000484785
ISSN: 1018-4813
PubMed: 9412791
WoS: A1997YK43800011
Scopus: 2-s2.0-0030733024
Институција/група
VinčaTY - JOUR AU - Alavantić, Dragan AU - Glišić, Sanja AU - Erceg, Slaven AU - Stupar, Milanko R. PY - 1997 UR - https://vinar.vin.bg.ac.rs/handle/123456789/2101 AB - We investigated common length polymorphism caused by a variable number of tandem repeats in the hypervariable region located at the 3 end of the human apolipoprotein B gene in 696 Serbian (Belgrade area) unrelated individuals of both genders. After using the polymerase chain reaction to amplify this polymorphic region, 17 different alleles, containing 22-54 repeats, were distinguished. The bimodal distribution and the heterozygosity index (average 0.71) obtained in both genders are similar to those reported for other Caucasian populations. However, the HVE34 allele was found to be the commonest in both female and male samples. There was also a lower frequency of the HVE GT 36 alleles than in other Caucasian populations studied. T2 - European Journal of Human Genetics T1 - Genetic variation at the apoB 3 hypervariable region in a Serbian population VL - 5 IS - 5 SP - 333 EP - 335 DO - 10.1159/000484785 UR - https://hdl.handle.net/21.15107/rcub_vinar_2101 ER -
@article{ author = "Alavantić, Dragan and Glišić, Sanja and Erceg, Slaven and Stupar, Milanko R.", year = "1997", abstract = "We investigated common length polymorphism caused by a variable number of tandem repeats in the hypervariable region located at the 3 end of the human apolipoprotein B gene in 696 Serbian (Belgrade area) unrelated individuals of both genders. After using the polymerase chain reaction to amplify this polymorphic region, 17 different alleles, containing 22-54 repeats, were distinguished. The bimodal distribution and the heterozygosity index (average 0.71) obtained in both genders are similar to those reported for other Caucasian populations. However, the HVE34 allele was found to be the commonest in both female and male samples. There was also a lower frequency of the HVE GT 36 alleles than in other Caucasian populations studied.", journal = "European Journal of Human Genetics", title = "Genetic variation at the apoB 3 hypervariable region in a Serbian population", volume = "5", number = "5", pages = "333-335", doi = "10.1159/000484785", url = "https://hdl.handle.net/21.15107/rcub_vinar_2101" }
Alavantić, D., Glišić, S., Erceg, S.,& Stupar, M. R.. (1997). Genetic variation at the apoB 3 hypervariable region in a Serbian population. in European Journal of Human Genetics, 5(5), 333-335. https://doi.org/10.1159/000484785 https://hdl.handle.net/21.15107/rcub_vinar_2101
Alavantić D, Glišić S, Erceg S, Stupar MR. Genetic variation at the apoB 3 hypervariable region in a Serbian population. in European Journal of Human Genetics. 1997;5(5):333-335. doi:10.1159/000484785 https://hdl.handle.net/21.15107/rcub_vinar_2101 .
Alavantić, Dragan, Glišić, Sanja, Erceg, Slaven, Stupar, Milanko R., "Genetic variation at the apoB 3 hypervariable region in a Serbian population" in European Journal of Human Genetics, 5, no. 5 (1997):333-335, https://doi.org/10.1159/000484785 ., https://hdl.handle.net/21.15107/rcub_vinar_2101 .